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Investigating ultrafast carrier dynamics in perovskite solar cells with an extended π-conjugated polymeric diketopyrrolopyrrole layer for hole transportation

Here, we show a new diketopyrrole based polymeric hole-transport material (PBDTP-DTDPP, (poly[[2,5-bis(2-hexyldecyl)-2,3,5,6-tetrahydro-3,6-dioxopyrrolo[3,4-c]pyrrole-1,4-diyl]-alt-[[2,2′-(4,8-bis(4-ethylhexyl-1-phenyl)-benzo[1,2-b:4,5-b′]dithiophene)bis-thieno[3,2-b]thiophen]-5,5′-diyl]])) for application in perovskite solar cells. The material performance was tested in a solar cell with an optim

Oxidative damage to lipids is rapidly reduced during migratory stopovers

Most migrating birds need to stopover in between flights in order to refuel. Lately, additional purposes of stopover have been suggested, including physiological recovery from metabolically demanding migratory flight. One apparently unavoidable, but harmful physiological effect of migratory flight is increased oxidative damage to lipids and proteins. We here, for the first time, tested whether mig

Unique spectral signature of human cutaneous squamous cell carcinoma by photoacoustic imaging

Cutaneous squamous cell carcinoma (cSCC) is a common skin cancer with metastatic potential. To reduce reoperations due to nonradical excision, there is a need to develop a technique for identification of tumor margins preoperatively. Photoacoustic (PA) imaging is a novel imaging technology that combines the strengths of laser optics and ultrasound. Our aim was to determine the spectral signature o

Middle ordovician carbonate facies development, conodont biostratigraphy and faunal diversity patterns at the Lynna River, northwestern Russia

The Ordovician Period has emerged as a highly dynamic time in Earth history. Comprehensive work on chrono, chemo-and biostratigraphy has resulted in an overall wellconstrained systemic framework, but several local successions around the globe still await detailed analysis in many respects. Herein we perform a highresolution analysis of abiotic and biotic signals in the Lynna River section, a key l

Label-free acoustophoretic enrichment of mononuclear cells from blood

We are reporting an efficient, label-free and continuous separation of mononuclear cells (MNC), from blood using microchip acoustophoresis. In standard PBS buffer, MNCs and red blood cells (RBC) display overlapping acoustophoretic mobilities which compromise separation of these cell types from each other. In this paper we capitalize on the fact that MNC and RBC display different acoustophysical pr

High water intake and low urine osmolality are associated with favorable metabolic profile at a population level : low vasopressin secretion as a possible explanation

Purpose: Elevated plasma concentration of the vasopressin marker copeptin and low water intake are associated with elevated blood glucose and diabetes risk at a population level. Moreover, in individuals with low urine volume and high urine osmolality (u-Osm), water supplementation reduced fasting plasma (fp) copeptin and fp-glucose. In this observational study, we investigated if low total water

Novel Retaining Glycoside Hydrolases : Potential candidates for transglycosylation and hydrolysis

Our society is moving towards renewable resources, where biomass, rich incarbohydrates, is producing chemicals and fuel. However, there are severallimitations when it comes to valorisation of the carbohydrates from renewablebiomass. One major hurdle is the over-functional nature of carbohydrates, making them difficult to process by conventional chemistry. Carbohydrate activeenzymes can help overco

On crack path stability in a layered material

Crack paths in an elastic layer on top of a substrate are considered. Crack growth is initiated from an edge crack in the layer. The plane of the initially straight crack forms an angle to the free surface. The load consists of a pair of forces applied at the crack mouth and parallel to the interface. Crack paths are calculated using a boundary element method. Crack growth is assumed to proceed al

Singleshot polychromatic coherent diffractive imaging with a high-order harmonic source

Singleshot polychromatic coherent diffractive imaging is performed with a high-intensity high-order harmonic generation source. The coherence properties are analyzed and several reconstructions show the shot-to-shot fluctuations of the incident beam wavefront. The method is based on a multi-step approach. First, the spectrum is extracted from double-slit diffraction data. The spectrum is used as i

Does passive sound attenuation affect responses to pitch-shifted auditory feedback?

The role of auditory feedback in vocal production has mainly been investigated by altered auditory feedback (AAF) in real time. In response, speakers compensate by shifting their speech output in the opposite direction. Current theory suggests this is caused by a mismatch between expected and observed feedback. A methodological issue is the difficulty to fully isolate the speaker’s hearing so that

Stakeholders, drivers and barriers for local electronics repair: a case study of southern Sweden

Promoting repair of electronics is an important strategy to slow material loops, particularly of critical raw materials, as part of a transition to a circular economy. This contribution accounts for a case study of southern Sweden conducted in order to examine drivers and barriers for repairing electronics, as well as better understand the roles of different stakeholders. Repair activities in the

Effects from usage of pre‑trip information and passenger scheduling strategies on waiting times in public transport: An empirical survey based on a dedicated smartphone application

Väntetider är viktiga indikatorer för graden av restidsoptimering och andra beteendemässiga aspekter bland kollektivtrafikresenärer. Såsom tidigare studier visar så är användningsgraden av avgångsinformation för avresa är en viktig faktor för att realisera potentialen i restidsminskningar genom att möjliggöra för resenärer att optimera sina väntetider. Huvuddelen av den empiriska forskningen hittiWaiting times are important indicators of the degree of travel time optimisation andother behavioural traits among public transport (PT) passengers. As previous studieshave shown, the level and usage of pre-trip information regarding schedule or realtime departures are important factors that infuence the potential to realise traveltime savings by enabling PT passengers to optimise waiting times. M

Physical bounds and radiation modes for MIMO antennas

Modern antenna design for communication systems revolves around two extremes: devices, where only a small region is dedicated to antenna design, and base stations, where design space is not shared with other components. Both imply different restrictions on what performance is realizable. In this paper a computationally efficient method for calculating the fundamental performance bound on spectral

Developmental cost theory predicts thermal environment and vulnerability to global warming

Metazoans must develop from zygotes to feeding organisms. In doing so, developing offspring consume up to 60% of the energy provided by their parent. The cost of development depends on two rates: metabolic rate, which determines the rate that energy is used; and developmental rate, which determines the length of the developmental period. Both development and metabolism are highly temperature-depen

The link between auditory salience and emotion intensity

To ensure that listeners pay attention and do not habituate, emotionally intense vocalizations may be under evolutionary pressure to exploit processing biases in the auditory system by maximising their bottom-up salience. This “salience code” hypothesis was tested using 128 human nonverbal vocalizations representing eight emotions: amusement, anger, disgust, effort, fear, pain, pleasure, and sadne

Modeling train-induced ground-borne vibrations using FEM in a moving frame of reference

To predict ground-borne vibration levels caused by railway traffic, models for estimating the load from the vibration source, as well as the vibration transmission through the ground, are needed. In the present paper, a finite element formulation in a frame of reference following the moving load, is used for modeling a railway slab track. The response of the underlying soil is represented through

Extensive clonal branching shapes the evolutionary history of high-risk pediatric cancers

Darwinian evolution of tumor cells remains underexplored in childhood cancer. We here reconstruct the evolutionary histories of 56 pediatric primary tumors, including 24 neuroblastomas, 24 Wilms tumors and 8 rhabdomyosarcomas. Whole genome copy number and whole exome mutational profiling of multiple regions per tumor was performed followed by clonal deconvolution to reconstruct a phylogenetic tree

Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients

Liquid biopsy allows assessment of multiple analytes, providing temporal information with potential for improving understanding of cancer evolution and clinical management of patients. Although liquid biopsies are intensely investigated for prediction and response monitoring, preanalytic variables are of primary concern for clinical implementation, including categories of collection method and sam