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Simulations of latex particles immersed in dendrimer solutions.
In this work, we present Monte Carlo simulations of mixtures containing negatively charged latex particles and positively charged dendrimers. We focus on the interaction between two latex particles as salt concentration, dendrimer dose, and generation number are varied. Interaction free energies and corresponding stability ratios are calculated. Minimal stability is found near the isoelectric poin
Volumetric and dosimetric evaluation of radiation treatment plans: radiation conformity index
PURPOSE: The use of conformal radiation therapy has grown substantially during the last years since three-dimensional (3D) treatment planning systems with beams-eye-view planning has become commercially available. We studied the degree of conformity reached in clinical routines for some common diagnoses treated at our department by calculating a radiation conformity index (RCI). METHODS AND MATERI
Standardization of Cystatin C: development of primary and secondary reference preparations.
A Primary Reference Preparation has been produced using pure, recombinant, Cystatin C in a solvent of 0.1 mol/L KCl. Dry mass determination of the Primary Reference Preparation resulted in a Cystatin C concentration of 5.20 g/L. Agarose-electrophoresis and SDS-electrophoresis, as well as N-terminal sequencing, verified the purity, homogeneity and identity of Cystatin C in the Primary Reference Pre
The opitz syndrome gene mid1 is transcribed from a human endogenous retroviral promoter.
Human endogenous retroviruses (HERVs) and other long terminal repeat (LTR)–containing elements comprise a significant portion (8%) of the human genome and are likely vestiges of retroviral infections during primate evolution. Many of the HERVs present in human DNA have retained functional promoter, enhancer, and polyadenylation signals, and these regulatory sequences have the potential to modify t
Low temperature Ga surface diffusion from focused ion beam milled grooves.
Ga diffusion from focused ion beam (FIB) milled grooves has been studied using x-ray photoemission electron microscopy (XPEEM) and mirror electron microscopy (MEM). We analyze the surface chemistry of the FIB structures measuring the Ga presence in the top layers of the milled grooves and morphological defects inside the grooves. The Ga is initially strictly confined to the grooves. However, annea
Species loss leads to community closure
Global extinction of a species is sadly irreversible. At a local scale, however, extinctions may be followed by re-invasion. We here show that this is not necessarily the case and that an ecological community may close its doors for re-invasion of species lost from it. Previous studies of how communities are assembled have shown that there may be rules for that process and that limitations are set
Testing for the Presence of Thermal Pretreatment of Flint in the Mesolithic and Neolithic of Sweden
Through ethnographic accounts, the method of heat treatment of silica materials to improve the flaking qualities is shown to have been known almost worldwide. Some mesolithic and neolithic flint artifacts from southern Sweden were examined in order to determine if they too were heat treated. From several methods proving or indicating thermal alteration of flint, analysis using scanning electron mi
Ex vivo evaluation of nonacceptable donor lungs
Background. Only a minority of the potential candidates for lung donation are considered suitable, using current evaluation methods. A new method for ex vivo evaluation, with the potential for reconditioning of marginal and nonacceptable lungs, has been developed. This is a report of the ex vivo evaluation of six donor lungs deemed nonacceptable (arterial oxygen pressure less than 40 kPa) by the S
Older people in persistent pain: nursing and paramedical staff perceptions and pain management.
Background. Persistent pain is a common problem for older people. Knowledge about how nursing and paramedical staff perceive these people and what they do to relieve the pain seems scarce. Aim. To explore nursing and paramedical staff perceptions of older people in persistent pain and their day-to-day management of pain. Methods. Interviews in Swedish with 52 nursing auxiliaries, Registered Nurs
Similar rates of exponential decrease in serum concentrations of free prostate-specific antigen (PSA), PSA complexed to alpha-1-antichymotrypsin, and human glandular kallikrein 2 (hK2) in prostate cancer patients treated with GnRH-analogues
BACKGROUND: Our recently reported finding of rapid bi-exponential elimination of free prostate-specific antigen (PSA) after radical retropubic prostatectomy in patients with moderately elevated PSA levels, which contrasted a very slow, linear elimination of PSA complexed to alpha-1-antichymotrypsin (ACT), prompted us to study whether these elimination rates were applicable for patients selected fo
Experimental quantum-state tomography of a solid-state qubit
Quantum-state tomography is used to characterize the state of an ensemble based qubit implemented through two hyperfine levels in Pr3+ ions, doped into a Y2SiO5 crystal. We experimentally verify that single-qubit rotation errors due to inhomogeneities of the ensemble can be suppressed using the Roos-Molmer dark-state scheme [Roos and Molmer, Phys. Rev. A 69, 022321 (2004)] Fidelities above > 90%,
Structure elucidation of the hepatitis B virus encapsidation signal by NMR on selectively labeled RNAs.
Hepatitis B virus (HBV) HBV is DNA virus with a unique replication strategy, which involves reverse transcription of its pregenomic RNA. Essential for this reverse transcription are the 5'- and 3'-ends of its pregenomic RNA (5'-RT-RNA and 3'-RT-RNA, respectively) which form conserved bulged stem-loop structures. The 5'-RT-RNA consists of a 67 nucleotide bulged stein-loop structure, epsilon, which
DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis.
Bird or bat: comparing airframe design and flight performance.
Birds and bats have evolved powered flight independently, which makes a comparison of evolutionary 'design' solutions potentially interesting. In this paper we highlight similarities and differences with respect to flight characteristics, including morphology, flight kinematics, aerodynamics, energetics and flight performance. Birds' size range is 0.002-15 kg and bats' size range is 0.002-1.5 kg.
Assessment of probabilistic system effects on the reliability of timber trusses
In structural engineering the system effect is known as the possibility of transversal collaboration among parallel load-bearing elements due to mechanical load sharing. The statistical system effect, related to the variation of strength within structural timber elements, is investigated in this paper. The system investigated is a roof truss of W-type. The strength variation within and between tim
Dormancy in freshwater zooplankton: Induction, termination and the importance of benthic-pelagic coupling
For a short-lived organism, such as a freshwater zooplankter, the ways of coping with years of local recruitment failure are either to disperse between habitats and recolonise or to disperse in time through diapause. Diapause is common among freshwater zooplankton and is generally seen as a way to escape periods of harsh environmental conditions. The egg-bank or pool of diapausing copepodites in l
Urothelial carcinoma in the prostatic urethra and prostate: current controversies
We reviewed the literature on urothelial carcinoma in the prostatic urethra and prostate. We concluded that the incidence of urothelial carcinoma in the prostatic urethra and prostate is probably underestimated. This fact warrants thorough follow-up of patients with high-risk bladder cancers and also whole-mount examination of the prostate after cystectomy to recognize the true incidence and exten
AFM manipulation of carbon nanotubes: realization of ultra-fine nanoelectrodes
We have investigated the possibility of using carbon nanotubes as flexible, mobile electrical probes able to electrically contact nanometre- scaled objects. Configurations with metal electrodes evaporated on top of multi-, few- and single-wall carbon nanotubes have been studied. Scanning probe manipulation was used to create nano-mechanical switches by first cutting the various tubes, and then mov
Influence of the fracture softening behaviour of wood on load-COD curve and R-curve
A cohesive crack model is used to analyse failure of wood in mode I along the grain. Several configurations of the gradual fracture softening behaviour of an interface, meshed with joint-elements located on the potential crack path, are investigated. Different constitutive laws, obtained from a single normalized polynomial function, are tested in order to estimate the influence of parameters such