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Structural details of a genome packaged in a viral capsid are essential for understanding how the structural arrangement of a viral genome in a capsid controls its release dynamics during infection, which critically affects viral replication. We previously found a temperature-induced, solid-like to fluid-like mechanical transition of packaged λ-genome that leads to rapid DNA ejection. However, an
We report the discovery of a third planet transiting the star TOI-1260, previously known to host two transiting sub-Neptune planets with orbital periods of 3.127 and 7.493 d, respectively. The nature of the third transiting planet with a 16.6-d orbit is supported by ground-based follow-up observations, including time-series photometry, high-angular resolution images, spectroscopy, and archival ima
Creation of business value is a major objective of any enterprise, but the way in whichvalue is created and its consequences call for re-evaluation in response to current sustainability goals. The agricultural sector serves basic human needs, but its systems and methods for production, processing, and consumption often pose challenges to sustainable development. To address these challenges, this s
The agricultural sector in Sweden, as elsewhere, is affected by increased intensification and specialisation, leading to fewer and larger farms. The majority of agricultural firms acquire profits by pushing an economies of scale strategy, which is not always possible for small farms. However, there are alternative strategies. This teaching case focuses on a small farm in Sweden and offers students
Value creation is at the core of business model (BM) research, but the link between BM and value creation remains unclear. In this work, empirical data on BM transformation towards sustainable value creation in the agri-food sector, were obtained through case studies. Factors in BM transformation were identified, transformations in different BM segments were analysed and sustainable value created
Specialization of agriculture in the Colombian Andes has increased smallholder vulnerability to climate change and global price fluctuations and has also affected the socio-economic and environmental conditions. Promoting sustainable agriculture in the region requires a holistic understanding of complex agroecosystems. This study identifies and analyzes the main challenges for agriculture and poss
Background: In suspected myocardial infarction (MI), guidelines recommend using high-sensitivity cardiac troponin (hs-cTn)-based approaches. These require fixed assay-specific thresholds and timepoints, without directly integrating clinical information. Using machine-learning techniques including hs-cTn and clinical routine variables, we aimed to build a digital tool to directly estimate the indiv
This paper describes an accelerated finite element-boundary integral code with support for complex media. The code is implemented in Python using several open source packages, and uses Numba just-in-time compilation for improved performance. To accelerate the boundary integral part of the code, a multilevel implementation of the adaptive cross approximation is used. As a numerical example, scatterThis paper describes an accelerated finite element-boundary integral code with support for complex media. The code is implemented in Python using several open source packages, and uses Numba just-in-time compilation for improved performance. To accelerate the boundary integral part of the code, a multilevel implementation of the adaptive cross approximation is used. As a numerical example, scatter
Background: The distribution of ovarian tumour characteristics differs between germline BRCA1 and BRCA2 pathogenic variant carriers and non-carriers. In this study, we assessed the utility of ovarian tumour characteristics as predictors of BRCA1 and BRCA2 variant pathogenicity, for application using the American College of Medical Genetics and the Association for Molecular Pathology (ACMG/AMP) var
This thesis examines the role of beamlines with publication metadata from the European Synchrotron Radiation Facility (ESRF a large scientific facility offering diverse conditions for scientific research. As a user-oriented Big Science facility, the ESRF channels extremely brilliant light into different experimental areas called beamlines that house specific instruments that cater to the needs of
In response to the climate emergency, the European Union seeks to establish a new model of inclusive growth and depicts this shift as a ‘green, fair and competitive transition’. The article examines the EU sustainable corporate governance initiative commenced in 2018 that has crystalized after 4 years in a Commission’s proposal for a Directive on corporate due diligence, which is expected to be ad
The implementation of continuous processing in the biopharmaceutical industry is hindered by the scarcity of process analytical technologies (PAT). To monitor and control a continuous process, PAT tools will be crucial to measure real-time product quality attributes such as protein aggregation. Miniaturizing these analytical techniques can increase measurement speed and enable faster decision-maki
This chapter examines the legislative and judicial dimensions of the digital rule of law in the EU and its current and future building. We argue that adjudication in EU law related to the digital rule of law is destined to grow as it is fostered by the new legislation in digitalisation and a proactive Court of Justice eager to interpret the rights enshrined under the Charter. The building of the d
Gen Z, Tourism, and Sustainable Consumption is the first book to provide a comprehensive account of Generation Z in relation to sustainable consumption practices and travel cultures. Gen Z is regarded as the world’s largest consumer market. The growth and behaviour of this economically significant market will have enormous implications for the future development of the tourism industry and destina
Vi befinner oss i en formativ period gällande AI-reglering där de beslut som tas kommer att ha stor påverkan för en väsentlig tid framåt, globalt, i Europa såväl som i Sverige. Syftet med den här rapporten är att analysera processen med framtagandet av den europeiska AI-förordningen, dvs. placera in AI-regleringsaspekter i ett bredare perspektiv. Det görs genom att belysa rättsliga utmaningar kopp
