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The big two dictionaries : Capturing agency and communion in natural language

Four studies developed and validated two dictionaries to capture agentic and communal expressions in natural language. Their development followed the Linguistic Inquiry and Word Count (LIWC) approach (Study 1) and we tested their validity with frequency-based analyses and semantic similarity measures. The newly developed Agency and Communion dictionaries were aligned with LIWC categories related t

A comparative study between D2Q9 and D2Q5 lattice Boltzmann scheme for mass transport phenomena in porous media

Characterization of different transport phenomena through porous media represents a key factor to improve mechanical or electrical properties of materials. Porous materials have several applications in different fields such as geological sciences, energy sciences or biological applications. Considering the difficulty to carry out experimental studies in porous media, these transport phenomena are

Montelukast, a CysLT1 receptor antagonist, reduces colon cancer stemness and tumor burden in a mouse xenograft model of human colon cancer

Inflammation is implicated in the etiology of sporadic colon cancer (CC), which is one of the leading causes of cancer-related deaths worldwide. Here, we report that inhibition of the inflammatory receptor CysLT1 through its antagonist, montelukast, is beneficial in minimizing stemness in CC and thereby minimizing tumor growth in a mouse xenograft model of human colon cancer. Upon treatment with m

First evidence of Archean mafic dykes at 2.62 Ga in the Yilgarn Craton, Western Australia : Links to cratonisation and the Zimbabwe Craton

The Archean Yilgarn Craton in Western Australia hosts at least five generations of Proterozoic mafic dykes, the oldest previously identified dykes belonging to the ca. 2408–2401 Ma Widgiemooltha Supersuite. We report here the first known Archean mafic dyke dated at 2615 ± 6 Ma by the ID-TIMS U-Pb method on baddeleyite and at 2610 ± 25 Ma using in situ SHRIMP U-Pb dating of baddeleyite. Aeromagneti

Abundance of gut Prevotella at baseline and metabolic response to barley prebiotics

Purpose: We previously showed that short-term intervention with barley kernel bread (BKB) improved glucose tolerance. However, glucose tolerance was not improved in a subset of individuals (non-responders) who were characterized by a low Prevotella/Bacteroides ratio. The purpose of the present study was to investigate if the baseline Prevotella/Bacteroides ratio can be used to stratify metabolic r

Applicability of Femtosecond Laser Electronic Excitation Tagging in Combustion Flow Field Velocity Measurements

Femtosecond laser electronic excitation tagging (FLEET) is a molecular tagging velocimetry technique that can be applied in combustion flow fields, although detailed studies of its application in combustion are still needed. We report the applicability of FLEET in premixed CH4–air flames. We found that FLEET can be applied in all of the combustion areas (e.g., the unburned region, the burned regio

Advantages, disadvantages and optimization of one-stage and chromogenic factor activity assays in haemophilia A and B

Haemophilia A and B diagnosis and disease severity classification are determined on the basis of results from factor VIII (FVIII) and factor FIX (FIX) activity assays, respectively. These assays are also used for potency labelling, postinfusion monitoring of factor replacement products and testing for FVIII/FIX inhibitors. This review focuses on activated partial thromboplastin time (APTT)-based o

Statins : a role in breast cancer therapy?

Statin drugs have been used for more than two decades to treat hypercholesterolemia and as cardio-preventive drugs, resulting in a marked decrease in cardiovascular morbidity and mortality worldwide. Statins halt hepatic cholesterol biosynthesis by inhibiting the rate-limiting enzyme in the mevalonate pathway, hydroxymethylglutaryl-coenzyme A reductase (HMGCR). The mevalonate pathway regulates a h

Bespoke Adaptation in Rural Africa? An Asset-Based Approach from Southern Ethiopia

Debates on adaptation in rural Africa rarely consider how responses to climate variability vary by wealth group. This study examines differences across wealth groups based on principal component analysis and cluster analysis triangulated with participatory methods. Results indicate that perceptions of weather variability and extreme events are detected by most households regardless of wealth statu

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Like many jurisdictions that have implemented a general anti-avoidance tax legislation (GAAR), Swedish tax law faces the challenge of accurately defining the conditions for distinguishing abusive situations from others, especially as the notion of ‘abuse of law’ does not exist in Swedish law. Defined as a process in which a taxpayer follows both the wording of the law and its jurisprudential appli

Outpatient comprehensive geriatric assessment : effects on frailty and mortality in old people with multimorbidity and high health care utilization

Background: Multimorbidity and frailty are often associated and Comprehensive Geriatric Assessment (CGA) is considered the gold standard of care for these patients. Aims: This study aimed to evaluate the effect of outpatient Comprehensive Geriatric Assessment (CGA) on frailty in community-dwelling older people with multimorbidity and high health care utilization. Methods: The Ambulatory Geriatric

Swedish consensus reached on recording, interpretation and reporting of neonatal continuous simplified electroencephalography that is supported by amplitude-integrated trend analysis

Continuous monitoring of electroencephalography (EEG), with a focus on amplitude-integrated EEG (aEEG), has been used in neonatal intensive care for decades. A number of systems have been suggested for describing and quantifying aEEG patterns. Extensive full-montage EEG monitoring is used in specialised intensive care units. The American Clinical Neurophysiology Society published recommendations f

Glucagon clearance is regulated by nutritional state : Evidence from experimental studies in mice

Aims/hypothesis: Given the importance of glucagon in the development of type 2 diabetes and as a potential therapeutic agent, the aim of this study was to characterise glucagon kinetics in mice and its regulation by the nutritional state. Methods: Anaesthetised C57BL/6 mice fed normal or high-fat diets, or fasted, were injected intravenously with glucagon (0.1, 0.3, 1.0, 10.0 or 20 μg/kg); blood s

Small ester combustion chemistry : Computational kinetics and experimental study of methyl acetate and ethyl acetate

Small esters represent an important class of high octane biofuels for advanced spark ignition engines. They qualify for stringent fuel screening standards and could be synthesized through various pathways. In this work, we performed a detailed investigation of the combustion of two small esters, MA (methyl acetate) and EA (ethyl acetate), including quantum chemistry calculations, experimental stud

Genetic risk of progression to type 2 diabetes and response to intensive lifestyle or metformin in prediabetic women with and without a history of gestational diabetes mellitus

OBJECTIVE: The Diabetes Prevention Program (DPP) trial investigated rates of progression to diabetes among adults with prediabetes randomized to treatment with placebo, metformin, or intensive lifestyle intervention. Among women in the DPP, diabetes risk reduction with metformin was greater in women with prior gestational diabetes mellitus (GDM) compared with women without GDM but with one or more