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The anandamide transport inhibitor AM404 activates vanilloid receptors

The possibility that the anandamide transport inhibitor N-(4-hydroxyphenyl)-5,8,11,14-eicosatetraenamide (AM404), structurally similar to the vanilloid receptor agonists anandamide and capsaicin, may also activate vanilloid receptors and cause vasodilation was examined. AM404 evoked concentration-dependent relaxations in segments of rat isolated hepatic artery contracted with phenylephrine. Relaxa

Involvement of sensory nerves in vasodilator responses to acetylcholine and potassium ions in rat hepatic artery

In the presence of ouabain (1 mM), acetylcholine and KCl (5 mM) evoked endothelium-independent relaxations in rat hepatic arteries. Treatment with capsaicin (10 μM), scopolamine (1 μM) or CGRP8-37 (3 μM) prevented these relaxations. Acetylcholine-induced relaxations in intact arterial segments in the presence of indomethacin (10 μM) and N(G)-nitro-L-arginine (0.3 mM) were only partially inhibited

Experimental and Theoretical Study of Phase Separation in Aqueous Solutions of Clouding Polymers and Carboxylic Acids

The phase behavior of different carboxylic acids/nonionic polymer/water systems has been studied. The carboxylic acids investigated are acetic acid, propionic acid, and butyric acid. The polymers used are a linear random copolymer of ethylene oxide and propylene oxide (UCON) and ethyl(hydroxyethyl)-cellulose (EHEC). These polymers display a lower critical solution temperature (LCST) in water. The

Nightwalkers Malmö

Det finns bara en regel när det gäller drömmar, spöken och proletärer: Var försiktig, de kommer bara fram på natten! Kom med oss och håll ögonen öppna – du drömmer redan, nu ska du falla i sömn!Genom en nattlig expedition, eller för att vara mer exakt en night-walk, undersöker vi drömmarna och mardrömmarna hos dem som en gång kallades “arbetare” eller “proletärer”. Natten undergräver dagens ordnin

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Environmental and climate hazards, such as floods, increasingly cause damages in cities and urbanised areas in Germany. The capacity of the impacted populations to cope with the outcome of related disasters is, amongst others, influenced by their vulnerability. Vulnerability reduction is thus key for creating social or structural resilience. This is particularly the case during post-disaster recov

The American paediatric evaluation of disability inventory (PEDI). Applicability of PEDI in Sweden for children aged 2.0-6.9 years

The American Paediatric Evaluation of Disability Inventory (PEDI) is a new instrument for evaluating functional performance in disabled children aged 6 months to 7.5 years. It was developed to determine a child's functional capacity and performance in three domains, self-care, mobility and social function, as reflected in scores on three scales: (i) functional skills (current capability in specifi