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Wiki collaboration in organizations: an exploratory study

The use of social media technologies in organizations has introduced novel ways of collaboration, communication, and knowledge sharing. In this respect, the present study is concerned with examining the use of one type of social media, the wiki technology, by members of several professional communities of practice to collaborate and share knowledge with each other. As such, it seeks to identify an

The Automagic Home

The automated and technologically enhanced home has been promoted in varying guises since the late 19th Century. Nowadays we hear much about smart homes in which new internet connected things are supposed to change daily domestic practices and routines. Are we really on the brink of something new? Will AI and robotic technology finally deliver the automagic home?

Asymmetric synthesis of a tricyclic benzofuran motif : A privileged core structure in biologically active molecules

An efficient synthetic strategy for the asymmetric synthesis of a hexahydrodibenzofuran core structure, with a quaternary stereogenic center, emerges by employing a chiral reduction using Corey's (S)-Me-CBS-oxazaborolidine reagent followed by a Mitsunobu reaction to set the stereochemistry. A Pd-mediated intramolecular Heck reaction concludes the tricyclic core structure. Finally, a Pd/C catalyzed

Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator

Because of the limitations and liabilities of current testosterone therapies, non-steroidal tissue-selective androgen receptor modulators may provide a clinically meaningful advance in therapy. Using a functional cell-based assay AC-262536 was identified as a potent and selective AR ligand, with partial agonist activity relative to the natural androgen testosterone. A 2-week chronic study in castr

General combinatorial synthesis of tertiary amines on solid support. A novel conditional release strategy based on traceless linking at nitrogen

A novel solid phase synthesis of tertiary amines involving iodide-induced cleavage of the N-O bond of resin bound alkoxyammonium intermediates is described. The quaternary intermediates were assembled via sequential reductive aminations followed by alkylation. Cleavage from the solid support was induced by iodide ion or base, to afford the target tertiary amines in excellent purity.

Evaluating the contribution of forest ecosystem services to societal welfare through linking dynamic ecosystem modelling with economic valuation

Trade-offs exist among the multiple ecosystem services (ES) generated by forests. Generally, wood production conflicts with the provisioning of public-good ES such as the storage of carbon, nutrient retention and conservation of biodiversity. Recognizing that forests generate both private- and public-good ES implies that forestry should be optimized to maximize the contribution of forests to socie

Distribution of 5‐hydroxytryptamine (serotonin) in the brain of the teleost Gasterosteus aculeatus L.

The distribution of serotoninergic neurons in the brain of the three‐spined stickleback was demonstrated with the indirect peroxidase‐antiperoxidase (PAP) immunohistochemical method with antibodies against serotonin. Serotoninergic perikarya were demonstrated in the brainstem reticular formation (nucleus raphe dorsalis, nucleus raphe medialis, and nucleus tegmenti dorsalis lateralis) and in the pe

The Parapineal Organ of Teleosts

A parapineal organ was found to be present in 21 teleost fishes belonging to 20 different families, but was absent in poecilids and cyprinodontids. The parapineal organ was situated on the left side of the brain and sent a nerve tract to the left habenular nucleus, except in Gadus, where a “parapineal organ” appeared to send a nerve tract into the pineal stalk. The parapineal organ of adult Gaster

Electron microscopic analysis of S‐antigen‐ and serotonin‐immuoreactive neural and sensory elements in the photosensory pineal organ of the salmon

Photoreceptor cells in the pineal complex of poikilothermic vertebrates are regarded as homologous with the neuroendocrine pinealocytes in the mammalian pineal organ. They possess an indolamine metabolism, and they contain a number of substances that are immunochemically similar to phototransduction‐related proteins otherwise found in photoreceptors of the lateral eye retina. Using correlative lig

To increase physical activity in sedentary patients with affective - or schizophrenia spectrum disorders - a clinical study of adjuvant physical therapy in mental health

Purpose: To understand if physical therapy in addition to individualized psychiatric specialist treatment could aid sedentary patients with schizophrenia spectrum disorders or affective spectrum disorders to become more physically active and also to identify assessments suitable for measuring physical activity, physical function and movement motivation. Materials and methods: In a longitudinal, cl

A moan of pleasure should be breathy : The effect of voice quality on the meaning of human nonverbal vocalizations

Prosodic features, such as intonation and voice intensity, have a well-documented role in communicating emotion, but less is known about the role of laryngeal voice quality in speech and particularly in nonverbal vocalizations such as laughs and moans. Potentially, however, variations in voice quality between tense and breathy may convey rich information about the speaker’s physiological and affec

Effect of synthesis methods on photoluminescent properties for CsPbBr3 nanocrystals : Hot injection method and conversion method

Multiple facile synthetic strategies for all inorganic perovskite CsPbBr3 nanocrystals (NCs) have been established and developed, profiting from their excellent performance and great potential applied in the field of photonic and optoelectronic. Here, CsPbBr3 NCs were synthesized by both hot injection method (method 1) and conversion method (method 2), and the discrepancy of their photophysical pr

A load frame for in situ tomography at PETRA III

A load frame for in situ mechanical testing is developed for the microtomography end stations at the imaging beamline P05 and the high-energy material science beamline P07 of PETRA III at DESY, both operated by the Helmholtz- Zentrum Geesthacht. The load frame is fully integrated into the beamline control system and can be controlled via a feedback loop. All relevant parameters (load, displacement

Institutions and venture capital

We survey the literature on venture capital and institutions and present a case study comparing the development of the venture capital market in the United States and Sweden. Our literature survey underscores that the legal environment, financial market development, the tax system, labor market regulations, and public spending on research and development correlate with venture capital activities a