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Positron Emission Tomography and Autoradiography Imaging of P-selectin Activation Using 68Ga-Fucoidan in Photothrombotic Stroke

Background: P-selectin is activated early after stroke, followed by a rapid decline. This time course can be used to generate important information on stroke onset. The latter is crucial for therapeutic decision-making of wake-up strokes (i.e. thrombolysis or not). Here, we evaluated the specific p-selectin inhibitor fucoidan labeled with gallium-68 (68Ga-Fucoidan) as an imaging biomarker for asse

Feminism in Vietnam: Women’s Studies, Gender Research, and Intersections

In this chapter we approach inequalities between women and men in Vietnam through the lens of feminism. We address the manner in which feminism is understood, observing intellectual currents that resonate with global trends in some respects and those reflecting conditions more specific to Vietnam in others. Affinities with global currents, for example, are seen in the ways in which Vietnamese inte

Before Förster. Initial excitation in photosynthetic light harvesting.

Electronic 2D spectroscopy allows nontrivial quantum effects to be explored in unprecedented detail. Here, we apply recently developed fluorescence detected coherent 2D spectroscopy to study the light harvesting antenna 2 (LH2) of photosynthetic purple bacteria. We report double quantum coherence 2D spectra which show clear cross peaks indicating correlated excitations. Similar results are found f

Physical mechanism on exciton-plasmon coupling revealed by femtosecond pump-probe transient absorption spectroscopy.

The unclear mechanism of exciton-plasmon coupling interaction in monolayer MoS2-Ag nanoparticles hybrid, as a longstanding target in molecular nanotechnology and catalysis, is systemically investigated with transmission spectra and femtosecond pump-probe transient absorption spectroscopy in this paper. The properties of exciton in monolayer MoS2 are strongly enhanced due to the local surface plasm

High Excitation Intensity Opens a New Trapping Channel in Organic–Inorganic Hybrid Perovskite Nanoparticles.

We investigated the excited-state dynamics of CH3NH3PbBr3 perovskite nanoparticles (NPs) and bulk crystals under various excitation intensity regimes using transient absorption spectroscopy. We confirmed the sub-band gap hole trap states with optical transition to the conduction band in both samples. In bulk crystals, the excited-state dynamics is independent of pump intensity. However, in NPs, pr

Investigation of the role of Mn dopant in CdS quantum dot sensitized solar cell.

Mn-doping into CdS quantum dots (QDs) has been demonstrated a useful way to enhance the power conversion efficiency (PCE) of quantum dot sensitized solar cells (QDSCs), the detailed systematic study is needed to get a better fundamental understanding. This work focuses on the study of the effects of Mn dopant on light harvesting, charge transfer, and charge collection of the solar cells. The resul

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal fluid (CSF) has been associated with Alzheimer's disease (AD). TREM2 plays a critical role in microglial activation, survival, and phagocytosis; however, the pathophysiological role of sTREM2 in AD is not well understood. Understanding the role of sTREM2 in AD may reveal new pathological mechanisms and lead to the iSoluble triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal fluid (CSF) has been associated with Alzheimer's disease (AD). TREM2 plays a critical role in microglial activation, survival, and phagocytosis; however, the pathophysiological role of sTREM2 in AD is not well understood. Understanding the role of sTREM2 in AD may reveal new pathological mechanisms and lead to the i

(f)Lex avionica; How soft law serves as an instrumental mediator between professional norms and the hard law regulation of European civil aviation maintenance

The regulation of safety in civil aviation in Europe has become subject to a process of juridification. The role of law in the pro-active perspective of European Aviation Safety Agency (EASA) governance, requires understanding how hard law and soft law interact. The rationality of regulatory systems can be regarded as the normative core from which different normative claims (norms) are deduced dep

Microplastics in a freshwater mussel (Anodonta anatina) in Northern Europe

Alarming amounts of microplastics have recently been shown to accumulate in the environment. Recent focus has been on synthetic material contaminating the marine environment, while effects on freshwater habitats and organisms have received less attention. We here confirm and analyse occurrence of microplastics in the duck mussel, Anodonta anatina, in a Swedish river. All analysed mussels contained

Flame-retardant polyvinyl alcohol/cellulose nanofibers hybrid carbon aerogel by freeze drying with ultra-low phosphorus

Polyvinyl alcohol/cellulose nanofibers hybrid aerogel was prepared under freeze drying method. To improve the aerogels' anti-combustion performance, 0.8 wt% microencapsulated ammonium polyphosphate (MCAPP) was loaded as the flame retardant. Aerogels with extremely low density (~0.06 g/cm3) and excellent mechanical performance (Young's modulus: 1.045 MPa) can be obtained. The resulted aerogel also

Large eddy simulation of turbulent heat transfer in a non-isothermal channel : Effects of temperature-dependent viscosity and thermal conductivity

In this work, we perform large eddy simulations (LES) to study the influence of variable viscosity and thermal conductivity on forced convection in a non-isothermal channel flow. To prevent thermal dilatational effect, the gas density is assumed to be constant. The temperature ratio T2/T1 is varied from 1.01 to 2.2, where T2 and T1 are the temperatures of hot and cold walls, respectively. The mean

Children with Hirschsprung's Disease and Syndromes with Cognitive Dysfunction : Manifestations, Treatment, and Outcomes

Introduction To assess differences in initial symptoms, treatments, and bowel function between children with Hirschsprung's disease (HD) with or without a cognitive dysfunction (CD). Materials and Methods The study included children with HD who underwent transanal endorectal pull-through. A retrospective chart review was performed to collect data on patient characteristics, diagnosis, and treatmen

Wound Infection after Laparoscopic-Assisted Gastrostomy in Infants

Background Gastrostomy placement in children is one of the most frequently performed pediatric surgical procedures and laparoscopic-assisted gastrostomy (LAG) is the preferred technique. Wound infection after LAG has become a significant concern due to the emergence of antibiotic resistance. The aim of this study was to describe the frequency of wound infection after LAG in children younger than 2

Progress in the use of genetic methods to study insect behavior outside Drosophila

In the span of a decade we have seen a rapid progress in the application of genetic tools and genome editing approaches in ‘non-model’ insects. It is now possible to target sensory receptor genes and neurons, explore their functional roles and manipulate behavioral responses in these insects. In this review, we focus on the latest examples from Diptera, Lepidoptera and Hymenoptera of how applicati

Striking a balance between the costs and benefits of increasing response capability : A microworld study of the effect of capability assessments

The Hyogo and Sendai frameworks highlight the key role of disaster risk management (DRM). However, the guidance is limited on how to best conduct DRM activities, such as capability assessments, to reduce the impact of disasters. In this study, we examine the effectiveness of different ways of presenting capability assessments, both when dealing with so-called high impact/low probability (HILP) eve

Association of urinary bisphenols and triclosan with thyroid function during early pregnancy

Background: Bisphenols and triclosan are considered as potential thyroid disruptors. While mild alterations in maternal thyroid function can result in adverse pregnancy and child developmental outcomes, there is still uncertainty whether bisphenols or triclosan can interfere with thyroid function during pregnancy. Objectives: We aimed to investigate the association of urinary bisphenol A (BPA), bi