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A momentary lapse of reason? Gezi in social-historical perspective

Through the social-historical contextualization of Gezi protests and drawing on the works of Badiou and Turner this article conceptualises the protests as a ‘happening’ or ‘event’ characterized by rupture and liminality. Without underestimating their importance as a meaning creation process, it is argued that the visions inspiring Gezi have been/are in sharp contrast to the version of democracy sh

Health-care quality and information failure : Evidence from Nigeria

Low-quality health services are a problem across low- and middle-income countries. Information failure may contribute, as patients may have insufficient knowledge to discern the quality of health services. That decreases the likelihood that patients will sort into higher quality facilities, increasing demand for better health services. This paper presents results from a health survey in Nigeria to

Search for heavy ZZ resonances in the ℓ+ℓ-ℓ+ℓ- and ℓ+ℓ- final states using proton–proton collisions at √s=13 TeV with the ATLAS detector

A search for heavy resonances decaying into a pair of Z bosons leading to ℓ+ℓ-ℓ+ℓ- and ℓ+ℓ- final states, where ℓ stands for either an electron or a muon, is presented. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 36.1 fb - 1 collected with the ATLAS detector during 2015 and 2016 at the Large Hadron Collider. Differe

Intraductal Papillary Mucinous Neoplasms of the Pancreas : A Nationwide Registry-Based Study

Background and Aims: To investigate the paraclinical and pathological features of surgically resected intraductal papillary mucinous neoplasms in Sweden. Materials and Methods: A review of prospectively collected data on patients undergoing pancreatic resection for a histopathologically verified intraductal papillary mucinous neoplasm between 2010 and 2016 was performed using the Swedish National

Partial Mediation by Cadmium Exposure of the Association between Tobacco Smoking and Atherosclerotic Plaques in the Carotid Artery

Exposure to cadmium confers increased cardiovascular risk. Tobacco smoke contains cadmium, which, hypothetically, may mediate parts of the tobacco-associated risk of developing atherosclerotic plaques. Baseline data from the Swedish Malmö Diet and Cancer cohort (1991-1996) were used to test this hypothesis. Mediation analysis was used to examine associations between smoking and blood cadmium level

rA1M-035, a Physicochemically Improved Human Recombinant α-Microglobulin, Has Therapeutic Effects in Rhabdomyolysis-Induced Acute Kidney Injury

AIMS: Human α1-microglobulin (A1M) is an endogenous reductase and radical- and heme-binding protein with physiological antioxidant protective functions. Recombinant human A1M (rA1M) has been shown to have therapeutic properties in animal models of preeclampsia, a pregnancy disease associated with oxidative stress. Recombinant A1M, however, lacks glycosylation, and shows lower solubility and stabil

Alpha-1-microglobulin protects from heme induced placenta and kidney damage in a pregnant ewe model for preeclampsia

INTRODUCTION: Previous gene expression analysis have identified fetal hemoglobin (HbF) as a plausible etiological factor in preeclampsia. Free hemoglobin and its degradation products, e.g. heme, are known to cause oxidative stress, tissue damage, and vaso-constriction, typical findings in preeclampsia.OBJECTIVE: To study alpha-1-microglobulin (A1M), an endogenous radical scavenger and heme-binder,

Acute tissue reactions, inner segment pathology, and effects of the antioxidant α1-microglobulin in an in vitro model of retinal detachment

The purpose of this study was to explore acute tissue reactions, ultrastructural photoreceptor morphology with emphasis on inner segments, and the effect of antioxidant treatment in an in vitro model of rhegmatogenous retinal detachment (RRD). A previously described method of RRD simulation was used with adult retinal porcine explants kept free-floating in culture medium with or without treatment

Gene expression profiling of first trimester placentas from pregnancies at high risk of developing preeclampsia

INTRODUCTION: Preeclampsia (PE) is an important cause of fetal and maternal morbidity and mortality. It is considered a two-stage disease, the first stage characterized by a defect placentation and the second stage by maternal manifestations. Details of the patho-physiology behind the transition from stage one to stage two remain unclear.OBJECTIVE: Was to study first trimester placental gene expre

Sources of Parent-Child Transmission of Drug Abuse : Path Analyses of Not-Lived-With Parental, Stepparental, Triparental, and Adoptive Families

To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the ef

Influence of APOA5 locus on the treatment efficacy of three statins : Evidence from a randomized pilot study in Chinese subjects

Pharmacogenetics or pharmacogenomics approaches are important for addressing the individual variabilities of drug efficacy especially in the era of precision medicine. One particular interesting gene to investigate is APOA5, which has been repeatedly linked with the inter-individual variations of serum triglycerides. Here, we explored APOA5-statin interactions in 195 Chinese subjects randomized to

A new framework to evaluate urban design using urban microclimatic modeling in future climatic conditions

Building more energy-efficient and sustainable urban areas that will both mitigate the effects of climate change and anticipate living conditions in future climate scenarios requires the development of new tools and methods that can help urban planners, architects and communities achieve this goal. In the current study, we designed a workflow that links different methodologies developed separately