Reliance on data for software systems engineering is increasing, e.g., to train machine learning applications. We foresee increasing costs for data collection and maintenance, leading to the risk of development budgets eaten up by commodity features, thus leaving little resources for differentiation and innovation. We therefore propose Open Collaborative Data (OCD) - a concept analogous to Open So

We consider the semiclassical Dirichlet Pauli operator in bounded connected domains in the plane. Rather optimal results have been obtained in previous papers by Ekholm–Kovařík–Portmann and Helffer–Sundqvist for the asymptotics of the ground state energy in the semiclassical limit when the magnetic field has constant sign. In this paper, we focus on the case when the magnetic field changes sign. W

Chemogenetics is the process of genetically expressing a macromolecule receptor capable of modulating the activity of the cell in response to selective chemical ligand. This chapter will cover the chemogenetic technologies that are available to date, focusing on the commonly available engineered or otherwise modified ligand-gated ion channels and G-protein-coupled receptors in the context of neuro

The four main findings about the age and abundance structure of the Milky Way bulge based on microlensed dwarf and subgiant stars are: (1) a wide metallicity distribution with distinct peaks at [Fe/H] = -1.09, -0.63, -0.20, +0.12, +0.41; (2) a high fraction of intermediate-age to young stars where at [Fe/H] > 0 more than 35 % are younger than 8 Gyr, (3) several episodes of significant star formati

Key message: A 6–9 month backward time shift of the carbon uptake gave the highest correlation between annual biomass increment and carbon uptake in this old even aged forest. Abstract: Plants’ carbon uptake and allocation to different biomass compartments is an important process for both wood production and climate mitigation. Measurements of the net ecosystem carbon dioxide exchange between ecos

Owing to their extreme crowding and high and variable extinction, stars in the Galactic Bulge, within ±2° of the Galactic plane, and especially those in the Nuclear Star Cluster, have only rarely been targeted for an analyses of their detailed abundances. There is also some disagreement about the high end of the abundance scale for these stars. It is now possible to obtain high dispersion, high S/

In the β-d-galactopyranoside-binding protein galectin-3, synthetic inhibitors substituted at the 3-position of a thiodigalactoside core cause the formation of an aglycone binding pocket through the displacement of an arginine residue (Arg144) from its position in the apoprotein. To examine in detail the role of different molecular interactions in this pocket, we have synthesized a series of nine 3

Introduction: The thrombin generation assay-calibrated automated thrombogram (TGA-CAT) method is used to measure the overall coagulation capacity in plasma. However, the method is still considered to be a research tool, mainly because of its’ lack of standardization. Aim: Our study aimed to further raise the standardization level for the TGA-CAT method by evaluating a detailed standardization prot

Background: To investigate changes in knee 3D bone shape over the first 5 years after acute anterior cruciate ligament (ACL) injury in participants of the randomized controlled KANON-trial. Methods: Serial MR images over 5 years from 121 young (32 women, mean age 26.1 years) adults with an acute ACL tear in a previously un-injured knee were analyzed using statistical shape models for bone. A match

Trisomy 7 as the single chromosome aberration has been found in a variety of neoplasms and in normal tissue in the proximity of tumors, as well as in non-neoplastic lesions. Recently, we described a nonrandom pattern of chromosome aberrations, in particular, a gain of chromosome 7, in synovia, cartilage, and osteophytes from patients with osteoarthritis. To study the clonal origin of trisomy 7 in

Innovation plays an important role in organization survival and longevity. This is especially true in the retail industry; there is a growing acknowledgment of the role of innovation in retail practice, as maintaining the status quo might prove insufficient, especially for traditional retailers, in addressing the enormous challenges they are facing driven by technological developments and evolving

Background: Clinical reasoning is the ability to integrate and apply different types of knowledge, weigh evidence critically and reflect upon the process to arrive at a diagnosis. Body awareness is an approach directed toward an awareness of how the body is used in terms of body function, behaviour, and interaction with self and others. Methods: In the present study, 36 physiotherapists (PTs) from

We describe a new and model-independent Lévy imaging method of quality fits to the published datasets and reconstruct the amplitude of high-energy pp and pp¯ elastic scattering processes. This method allows us to determine the excitation function of the shadow profile P(b), the elastic slope B(t) and the nuclear phase ϕ(t) functions of pp and pp¯ collisions directly from the data. Surprisingly, no

Among the many unique flight behaviours of Common Swifts Apus apus, the most puzzling may be their ascents to high altitudes during both dusk and dawn. Twilight ascents have been hypothesized to be functionally related to information acquisition, including integration of celestial orientation cues, high-altitude visual landmarks and sampling of weather conditions. However, their exact purpose rema

After a spout of optimism surrounding Myanmar's so-called democratic transition in the post-2010 period, civil-society organisations and academics are beginning to highlight rampant and violent resource grabs unfolding across the country. Delving into the Northern Tanintharyi landscape in the Southeast, this article aims to understand interrelated dynamics of coastal and agrarian transformation du

Systemic lupus erythematosus (SLE, OMIM 152700) is a systemic autoimmune disease with a complex etiology. The mode of inheritance of the genetic risk beyond familial SLE cases is currently unknown. Additionally, the contribution of heterozygous variants in genes known to cause monogenic SLE is not fully understood. Whole-genome sequencing of DNA samples from 71 Swedish patients with SLE and their

Ur ett strukturcykliskt perspektiv sker en omvandling av ekonomi, institutioner och politik under omvandlingsperioderna. Då välfärd kan betraktas som en funktion av dessa borde det vara möjligt att analysera välfärd och de institutionella arrangemang som är nödvändiga för en välfärdsproduktion med hjälp av en strukturcyklisk ansats. Lennart Schön har i ett flertal studier diskuterat detta samband,

Remissvaret utgår från utredningens sammanfattning och kommenterar under ett urval av dess rubriker. Under varje rubrik i sammanfattningen ger vi våra syn-punkter.Vi har valt att inte kommentera utredningens enskilda förslag till förändrad lag-stiftning, utan istället kommentera utifrån sammanfattningen av utredningen. An-ledningen är att vi inte anser att utredningen håller en sådan kvalitet att

We present an overview of the distributions of 11 elemental abundances in the Milky Way's (MW) inner regions, as traced by APOGEE stars released as part of the Sloan Digital Sky Survey Data Release 14/15 (DR14/DR15), including O, Mg, Si, Ca, Cr, Mn, Co, Ni, Na, Al, and K. This sample spans ∼4000 stars with R GC ≤ 4.0 kpc, enabling the most comprehensive study to date of these abundances and their