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Twisted Ribbon Aggregates in a Model Peptide System

The model peptides A 8 K and A 10 K self-assemble in water into ca. 100 nm long ribbon-like aggregates. These structures can be described as β-sheets laminated into a ribbon structure with a constant elliptical cross-section of 4 by 8 nm, where the longer axis corresponds to a finite number, N ≠15, of laminated sheets, and 4 nm corresponds to a stretched peptide length. The ribbon cross-section

Local Environmental Conditions Shape Generalist But Not Specialist Components of Microbial Metacommunities in the Baltic Sea

Marine microbes exhibit biogeographical patterns linked with fluxes of matter and energy. Yet, knowledge of the mechanisms shaping bacterioplankton community assembly across temporal scales remains poor. We examined bacterioplankton 16S rRNA gene fragments obtained from Baltic Sea transects to determine phylogenetic relatedness and assembly processes coupled with niche breadth. Communities were ph

Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, Ten-m, and D-laminin α2

Two new potential ligands of the Drosophila PS2 integrins have been characterized by functional interaction in cell culture. These potential ligands are a new Drosophila laminin α2 chain encoded by the wing blister locus and Ten-m, an extracellular protein known to be involved in embryonic pattern formation. As with previously identified PS2 ligands, both contain RGD sequences, and RGD-containing

Using two jet events to understand hadronization

While the hard phase of the strong interaction is well described by perturbative QCD, the soft hadronization phase is less understood. Benefiting from the high statistics from e+e− experiments at the Z0 resonance, it is possible to impose strong two-jet cuts on the data without losing the statistical significance. In these events perturbative activity is suppressed and hadronization effects can be

Nerve-dependent and -independent tenascin expression in the developing chick limb bud

The extracellular matrix protein, tenascin, appears in a restricted pattern during organ morphogenesis. Tenascin accumulates along developing peripheral nerves as they leave the spinal cord and enter the limb mesenchyme (Wehrle and Chiquet, Development 110, 401-415, 1990). Here we found that most but not all tenascin deposited along growing nerves is of glial origin. By in situ hybridization with

Infrared singularities in one-loop amplitudes

In this talk we discuss a purely numerical approach to next-to-leading order calculations in QCD. We present a simple formula, which provides a local infrared subtraction term for the integrand of a one-loop amplitude. In addition we briefly comment on local ultraviolet subtraction terms and on the required deformation of the contour of integration.

Numerical NLO QCD calculations

We present an algorithm for the numerical calculation of one-loop QCD amplitudes. The algorithm consists of subtraction terms, approximating the soft, collinear and ultraviolet divergences of one-loop amplitudes and a method to deform the integration contour for the loop integration into the complex space. The algorithm is formulated at the amplitude level and does not rely on Feynman graphs. Ther

Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC tran

Silent Timber Build - Development of low frequency vibroacoustic prediction tools for lightweight wooden constructions

The goal of the Silent Timber Build project is to develop new prediction tools for timber structures. As a matter of fact, impact sound insulation in the low frequency range is a crucial point concerning satisfaction of lightweight wooden-based building residents. Floor systems are rather complex: multi-layered, multi-cavity, stiffened, with floor covering and ceiling (either rigidly connected, su

Self-organizing networks for extracting jet features

Self-organizing neural networks are briefly reviewed and compared with supervised learning algorithms like back-propagation. The power of self-organization networks is in their capability of displaying typical features in a transparent manner. This is successfully demonstrated with two applications from hadronic jet physics; hadronization model discrimination and separation of b, c and light quark

Spin–orbit-coupled Bose–Einstein-condensed atoms confined in annular potentials

A spin–orbit-coupled Bose–Einstein-condensed cloud of atoms confined in an annular trapping potential shows a variety of phases that we investigate in the present study. Starting with the non- interacting problem, the homogeneous phase that is present in an untrapped system is replaced by a sinusoidal density variation in the limit of a very narrow annulus. In the case of an untrapped system there