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BACKGROUND: The risk of venous thromboembolism is high after total hip arthroplasty and could persist after hospital discharge. Our aim was to compare the use of rivaroxaban for extended thromboprophylaxis with short-term thromboprophylaxis with enoxaparin.METHODS: 2509 patients scheduled to undergo elective total hip arthroplasty were randomly assigned, stratified according to centre, with a comp

BACKGROUND: We investigated the efficacy of rivaroxaban, an orally active direct factor Xa inhibitor, in preventing venous thrombosis after total knee arthroplasty.METHODS: In this randomized, double-blind trial, 2531 patients who were to undergo total knee arthroplasty received either oral rivaroxaban, 10 mg once daily, beginning 6 to 8 hours after surgery, or subcutaneous enoxaparin, 40 mg once

A dilemma that the iconographer is often faced with when it comes to medieval imagery is what the fantastic hybrid animals actually represent. What are they? What do they mean? On the outer walls of the mid 11th century church of Vä, in north-eastern Scania, there are a number of sadly withered reliefs that may be interpreted as representing a number of different mythological animals with complete

This short article deals with the etymologies of two Perso-Arabic loans that function as technical terms in Tājika (Indian astrology imported from the Perso-Arabic cultural area), both appearing in the works of the 13th century CE astrological author Samarasiṃha. The terms are kṣuta-/kṣut- (“Inimical”) and vidumāla- (“Retrograde”) - the meanings of both have been clear for some time, but the artic

Building on the base of the existing telescopes of the Event Horizon Telescope (EHT) and ALMA, the next-generation EHT (ngEHT) aspires to deploy ∼10 more stations. The ngEHT targets an angular resolution of ∼15 microarcseconds. This resolution is achieved using Very Long Baseline Interferometry (VLBI) at the shortest radio wavelengths ∼1 mm. The Submillimeter Array (SMA) is both a standalone radio

Skuldtyngd är ett fyraårigt forskningsprojekt som startade 2021 i samarbete mellan Lunds universitet och Göteborgs universitet. Projektet är finansierat av Forte och studerar skuldsättningsproblem bland unga vuxna i åldern 18 till 25 år. Centralt för projektet är att förstå skuldsättningen ur unga vuxnas eget perspektiv, liksom att studera skuldsättning som ett socialt och relationellt fenomen som

Database gathering the archaeological and epigraphic materials relating to the cults of Mater Magna and Attis in Hispania

Tungsten (W) is a leading candidate for plasma-facing materials in fusion reactors. Recently, experiments have shown that during neutron irradiation, W and its transmutation products, mainly rhenium (Re), will form precipitates of the σ and χ types. This study identifies close-packed planes of the σ - and χ-phases in the W-Re system and uses ab-initio methods to identify mechanical properties such

A 38-year-old woman with type 1 diabetes, whose fasting plasma glucose levels were >500 mg/dL under 176 U/day of subcutaneous insulin injection, was admitted to Nippon Medical School Hospital, Tokyo, Japan. When insulin was administered intravenously, she was able to maintain favorable glycemic control even under 24 U/day of regular insulin, showing that she was accompanied by subcutaneous insulin

AIMS/INTRODUCTION: An increased risk of diabetes mellitus has been reported in primary aldosteronism, but the pathogenesis of glucose intolerance between the primary aldosteronism subtypes remains unclear. This study aimed to evaluate glucose metabolism in oral glucose tolerance test between aldosterone-producing adenoma and idiopathic hyperaldosteronism, and characterize patients with improved gl

AIMS/HYPOTHESIS: Obesity caused by overeating plays a pivotal role in the development of type 2 diabetes. However, it remains poorly understood how individual meal size differences are determined before the development of obesity. Here, we investigated the underlying mechanisms in determining spontaneous food intake in newly established Oikawa-Nagao Diabetes-Prone (ON-DP) and Diabetes-Resistant (O

BACKGROUND: A prolonged QT interval plays a causal role in fatal arrhythmia and is known to be a risk factor for sudden cardiac death. Although diabetic patients with microvascular complications tend to have a longer QT interval, the therapeutic effect of diabetes on the QT interval remains unclear. Here, we assessed the changes in QT interval in patients with type 2 diabetes (T2D) who received mu

Smoking during pregnancy is one of the causes of low birthweight. Ingestion of nicotine during pregnancy has various metabolic impacts on the fetus and offspring. According to the developmental origins of health and disease theory, low birthweight is a risk factor for developing various non-communicable diseases, including diabetes. We hypothesized that when nicotine-induced low-birthweight rats,

BACKGROUND: Perioperative hyperglycemia is a risk factor for postoperative complications in the general population. However, it has not been clarified whether perioperative hyperglycemia increases postoperative complications in patients with type-2 diabetes mellitus (T2D). Therefore, we aimed to analyze the relationship between perioperative glycemic status and postoperative complications in non-i

PURPOSE: Isolated adrenocorticotropic hormone deficiency is a rare disease; however, since immune check point inhibitors (ICIs) have become widely used, many more cases have been reported. In this study, we compared the human leukocyte antigen (HLA) signatures between ICI-induced isolated adrenocorticotropic hormone deficiency (IAD) and idiopathic IAD (IIAD).DESIGN AND METHODS: Clinical features a

Sitagliptin has been suggested as a treatment option for older adults with type 2 diabetes (T2D). However, no randomized controlled trial has been performed to evaluate the efficacy and safety of sitagliptin treatment in older Japanese patients with T2D. The STREAM study was a multicenter, open-label, randomized controlled trial. T2D outpatients aged 65-80 years with moderately controlled glycemic