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Bedömning av neurologisk prognos efter hjärtstopp : Uppdaterade rekommendationer från Svenska HLR-rådets expertgrupp

European Resuscitation Council (ERC) issued updated guidelines for postresuscitation care in 2015. This paper provides updated Swedish recommendations for neurological prognostication of patients remaining unconscious after cardiac arrest (CA). The prognostication should be based on independent methods; clinical and neurophysiological examinations, imaging and biomarkers. It should not be performe

Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes : Mendelian randomization study

Objective: To implement a mendelian randomization (MR) approach to determine whether type 2 diabetes mellitus (T2D), fasting glucose, fasting insulin, and body mass index (BMI) are causally associated with specific ischemic stroke subtypes. Methods: MR estimates of the association between each possible risk factor and ischemic stroke subtypes were calculated with inverse-variance weighted (convent

Simultaneous patch testing with fragrance mix I, fragrance mix II and their ingredients in southern Sweden between 2009 and 2015

Background: Fragrance mix I (FM I) and fragrance mix II (FM II) are included in the European baseline series as screening substances for fragrance contact allergy. Objectives: To investigate the frequency of allergic reactions to FM I, FM II and their ingredients in consecutively patch tested patients. Materials and methods: A retrospective analysis of data from 4430 patients patch tested between

Wind turbine noise effects on sleep: The WiTNES study

Onshore wind turbines are becoming increasingly widespread globally, with the associated net effect that a greater number of people will be exposed to wind turbine noise (WTN). Sleep disturbance by WTN has been suggested to be of particular importance with regards to a potential impact on human health. Within the Wind Turbine Noise Effects on Sleep (WiTNES) project, we have experimentally investig

Cohabitants’ perspective on housing adaptations: a piece of the puzzle

As part of the Swedish state-funded healthcare system, housing adaptations are used to promote safe and independent living for disabled people in ordinary housing through the elimination of physical environmental barriers in the home. The aim of this study was to describe the cohabitants’ expectations and experiences of how a housing adaptation, intended for the partner, would impact their everydaAs part of the Swedish state-funded healthcare system, housing adaptations are used to promote safe and independent living for disabled people in ordinary housing through the elimination of physical environmental barriers in the home. The aim of this study was to describe the cohabitants' expectations and experiences of how a housing adaptation, intended for the partner, would impact their everyda

Rate of Absorption for CO2 Absorption Systems Using a Wetted Wall Column

Knowledge on the absorption rate of CO2 in absorption systems is essential for accurate equipment design. This work is focused on determining the rate of absorption for novel absorption systems using a wetted wall column. This is a widely used method for determining the absorption flux of carbon dioxide in amine solutions. Two absorption systems were investigated, namely aqueous solutions of monoe

Risk of low bone mineral density in testicular germ cell cancer survivors : Association with hypogonadism and treatment modality

The cure rate of testicular cancer exceeds 95%, but testicular cancer survivors (TCS) are at increased risk of hypogonadism (HG). It has been suggested that TCS have reduced bone mineral density (BMD), but it is unclear whether this is related to HG or a direct effect of cancer therapy. The aim of this study was to evaluate whether TCS have decreased BMD, and if BMD is related to HG and/or the can

Crystallization Kinetics of AMP Carbamate in Solutions of AMP in Organic Solvents NMP or TEGDME

Novel CO2 capture systems, consisting of 2-amino-2-methyl-1-propanol (AMP), a sterically hindered amine, in the organic solvents N-methyl-2-pyrrolidone (NMP) or triethylene glycol dimethyl ether (TEGDME) have been under investigation as an economical solution to the post combustion carbon capture problem. The carbamate formed during reaction with CO2 may precipitate during absorption and be regene

Variation in aluminium patch test reactivity over time

Background: Contact allergy to aluminium has been reported more frequently in recent years. It has been pointed out that positive patch test reactions to aluminium may not be reproducible on retesting. Objectives: To investigate possible variations in patch test reactivity to aluminium over time. Methods: Twenty-one adults, who had previously reacted positively to aluminium, were patch tested with

Effects of oxygen therapy on wall-motion score index in patients with ST elevation myocardial infarction-the randomized SOCCER trial

Background: Although oxygen (O2) is routinely used in patients with acute myocardial infarction (AMI), it may have negative effects. In this substudy of the SOCCER trial, we aimed to evaluate the effects of O2-treatment on myocardial function in patients with ST elevation myocardial infarction (STEMI). Methods: Normoxic (≥94%) STEMI patients were randomized in the ambulance to either supplemental

Circulating tumor cells in patients with advanced urothelial carcinoma of the bladder : Association with tumor stage, lymph node metastases, FDG-PET findings, and survival

Background: There are currently no methods in clinical use that can detect early systemic dissemination of urothelial tumor cells. Objective: To evaluate measurement of circulating tumor cells (CTCs) as a biomarker for disseminated disease in patients with advanced bladder cancer. Design, setting, and participants: Between March 2013 and October 2015, 88 patients were prospectively included in the

Exploration of the active site of β4GalT7 – Synthesis of substrates and inhibitors

Ytan av alla celler är dekorerad med kolhydrater som står för mycket av den information en cell överför till omgivande celler. Många av kolhydraterna tillhör en föreningsklass som kallas proteoglykaner som består av ett protein sammanbundet med en eller flera långa kolhydratkedjor. Dessa kolhydratkedjor kallas glykosaminoglykaner och är bundna till proteinet via kolhydraten xylos. Än så länge har β-1,4-Galactosyltransferase 7 (β4GalT7) is a key enzyme in the biosynthesis of proteoglycans (PGs) and glycosaminoglycan (GAG) chains, which are important macromolecules involved in many biological processes such as cell growth and cell signaling as well as in cancer pathobiology and viral and bacterial infections. Despite its pivotal role, much is still unknown regarding the specific structure of

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This article discusses employment of crowds to make the change in Yemen.

Parameter Estimation - in sparsity we trust

This thesis is based on nine papers, all concerned with parameter estimation. The thesis aims at solving problems related to real-world applications such as spectroscopy, DNA sequencing, and audio processing, using sparse modeling heuristics. For the problems considered in this thesis, one is not only concerned with finding the parameters in the signal model, but also to determine the number of siThis thesis is based on nine papers, all concerned with parameter estimation. The thesis aims at solving problems related to real-world applications such as spectroscopy, DNA sequencing, and audio processing, using sparse modeling heuristics. For the problems considered in this thesis, one is not only concerned with finding the parameters in the signal model, but also to determine the number of si

Organizing for teamwork in healthcare : an alternative to team training?

Purpose: The purpose of this paper is to explore how organizational design could support teamwork and to identify organizational design principles that promote successful teamwork. Design/methodology/approach: Since traditional team training sessions take resources away from production, the alternative approach pursued here explores the promotion of teamwork by means of organizational design. A wi

Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy

Resistance to systemic therapy is a major problem in metastatic breast cancer (MBC) that can be explained by initial tumor heterogeneity as well as by evolutionary changes during therapy and tumor progression. Circulating tumor cells (CTCs) detected in a liquid biopsy can be sampled and characterized repeatedly during therapy in order to monitor treatment response and disease progression. Our aim

Intraneural glomus tumor of "uncertain malignant potential" and with BRAF mutation in the median nerve - an unusual case

A glomus tumor of uncertain malignant potential is defined as a glomus tumor with some, but not all, criteria for malignancy and without a known metastasis. Here, we present a rare example presenting in the median nerve in a 40-year-old woman with a long history of severely impaired left median nerve function. A large panel of immunohistochemical stains excluded other diagnoses, and the designatio