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Quality of life and resource utilization-Swedish data from the Care of Late-Stage Parkinsonism (CLaSP) study

Background: Few studies have investigated the health-related quality of life (HRQoL), resource use and costs in patients with late-stage Parkinson's disease (PD), and data from the Swedish setting are scarce. Objectives: First, we analyse the HRQoL in late-stage PD in Sweden. Second, we analyse the resource use and costs per severity level. Third, we analyse the relationship between costs and phys

The Enduring Popularity of the Euro throughout the Crisis

This paper analyses the evolution of public support for the euro from 1990 to 2011, using a popularity function approach, focusing on the most recent period of the financial and sovereign debt crisis. Exploring a huge database of close to half a million observations, covering the 12 original euro area member countries, we find that the ongoing crisis has only marginally reduced citizens’ support f

Crisis and Public Support for the Euro

The Eurozone crisis has meant slow growth, rising unemployment and social unrest. This contribution gauges the impact of these negative developments on European citizens’ opinion about the euro and the EU institutions. Using Eurobarometer surveys, the authors find that, within the Eurozone, the crisis has only marginally lowered support for the euro but has led to a sharp fall in public trust in t

Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein

Dimethyl sulfoxide (DMSO) is a highly utilized small molecule that serves many purposes in scientific research. DMSO offers unique polar, aprotic and amphiphilic features, which makes it an ideal solvent for a wide variety of both polar and nonpolar molecules. Furthermore, DMSO is often used as a cryoprotectant in cell-based research. However, recent reports suggest that DMSO, even at low concentr

Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601

Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16

Den förste hemiten

Redogörelse för de tidiga lundensiska (och i någon mån uppsaliensiska) studenthemmens tillkomst kopplad till en biografisk skiss över den förste "hemiten" (boende på Thomanders studenthem), Emil Sommarin, respektive ett resonemang huruvida denne kan ses som en "typisk" hemit.

High-connectivity quantum processor nodes using single-ion qubits in rare-earth-ion-doped crystals

We present two protocols for constructing quantum processor nodes in randomly doped rare-earth-ion crystals and analyze their properties. By varying the doping concentration and the accessible laser tunability, the processor nodes can contain anywhere from only a few tens to almost 1000 qubits. Furthermore, the average number of qubits each qubit can interact with, denoted by the connectivity, can

Does Engaging in Data Philanthropy Impact Business Value?

Data philanthropy (DP) is a new but much-lauded phenomenon. Extant DP research has been either conceptual, exploratory, and/or qualitative. The present study seeks to examine the business value of data philanthropy to the donor firm. We use an event study method to analyze stock performance of public firms associated with data philanthropy activities to determine if a link exists. We find signific

Perception of COVID-19 impacts on the construction industry over time

The emergence of COVID-19 has been changing in the world since 2020 and prompted social, cultural, and economic systems to adjust their structures, routines, and processes. The economic aspects of the pandemic appeared soon, and many industries changed their workflow and procedures through a mandatory or recommended quarantine. Knowing the impact of COVID-19 on different areas of construction proj

Road safety beyond the automobility norm? : Can Swedish road safety policy escape the automobility norm and facilitate cycling instead - lessons from the Netherlands

Road safety policy rules us in both visible and invisible ways and prioritising one mode often means downgrading another. It has been argued in previous research that road safety policy prioritises car traffic and in that way sustains the automobility norm. This paper focuses on the automobility norm that permeates Swedish road safety policy and how this hampers planning for cycling. It aims to co

Hospital Admission Rate, Cumulative Hospitalized Days, and Time to Admission Among Older Persons With Substance Use and Psychiatric Conditions

Background: Substance use among older persons occurs with medical and psychiatric comorbidities. This study examined the associations of substance use disorder (SUD), psychiatric, and dual diagnoses with 12-month cumulative hospitalized days, hospital admission rate and number of days to first hospitalization.Methods: The cohort of 3,624 individuals (28.2% women) aged 50 years or older was assesse

The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses

Human papillomaviruses (HPV) are epitheliotropic DNA tumor viruses that are prevalent in the human population. A subset of the HPVs termed high-risk HPVs (HR-HPVs) are causative agents of anogenital cancers and head-and-neck cancers. Cancer is the result of persistent high-risk HPV infections that have not been cleared by the immune system of the host. These infections are characterized by dysregu

Meat intake is associated with a higher risk of ulcerative colitis in a large European prospective cohort study

BACKGROUND AND AIMS: We aimed to investigate the association between protein intake and risk of inflammatory bowel disease (IBD) in the European Prospective Investigation into Cancer and Nutrition.METHODS: 413 593 participants from eight European countries were included. Dietary data were collected at baseline from validated food frequency questionnaires. Dietary data were calibrated to correct er

Shape Matters in Magnetic-Field-Assisted Assembly of Prolate Colloids

An anisotropic colloidal shape in combination with an externally tunable interaction potential results in a plethora of self-assembled structures with potential applications toward the fabrication of smart materials. Here we present our investigation on the influence of an external magnetic field on the self-assembly of hematite-silica core-shell prolate colloids for two aspect ratios ρ = 2.9 and