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Both experimental and simulation data on fire evacuation are influenced by a component of uncertainty caused by the impact of the unexplained variance in human behaviour, namely behavioural uncertainty (BU). Evacuation model validation studies should include the study of this type of uncertainty during the comparison of experiments and simulation results. An evacuation model validation procedure i
P>Background The long-term efficacy of infliximab as rescue therapy in steroid-refractory ulcerative colitis is not well described. Aim To examine the long-term efficacy of infliximab as a rescue therapy through a 3-year follow-up of a previous placebo-controlled trial of infliximab in acute steroid-refractory ulcerative colitis. Method In the original study, 45 patients were randomized to a singl
The interactions of the ECM (extracellular matrix) protein asporin with ECM components have previously not been investigated. Here, we show that asporin binds collagen type I. This binding is inhibited by recombinant asporin fragment LRR (leucine-rich repeat) 10-12 and by full-length decorin, but not by biglycan. We demonstrate that the polyaspartate domain binds calcium and regulates hydroxyapati
Popular Abstract in English Morphologically marked case is a salient Standard Arabic feature without parallel in Arabic dialects. As such it is a grammatical system learned by native speakers of Arabic through formal education. Case endings are traditionally regarded as an essential feature of Standard Arabic, but morphological case endings are used only sporadically in extemporaneous speech in foMorphologically marked case is a salient Standard Arabic feature without parallel in Arabic dialects. As such it is a grammatical system learned by native speakers of Arabic through formal education. Case endings are traditionally regarded as an essential feature of Standard Arabic, but morphological case endings are used only sporadically in extemporaneous speech in formal situations where Standa
While higher education is expected to prepare students so they can reflect and act in relation with a changing world, many structural forces instead favour procedural learning. There are fundamental contradictions between the aim of independent thinking and using standardised assessment, as well as between reasoning/speaking as an emancipatory force, and teaching as explanation. Other contradictio
Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of African ancestry compared to women of European ancestry. In search of common risk alleles for ER-negative breast cancer, we combined genome-wide association study (GWAS) data from women of African ancestry (1,004 ER-negative cases and 2,745 controls) and European ancestry (1,718 ER-negative cases and 3,670 controls)
Processes leading to a final state with at least two high transverse momentum leptons (electrons or muons) are studied using the full e(+/-) p data sample collected by the H1 experiment at HERA. The data correspond to an integrated luminosity of 463 pb(-1). Di-lepton and tri-lepton event classes are investigated. Cross sections of the production of e(+)e(-) and mu(+)mu(-) pairs are derived in a re
Partially premixed combustion has the potential of high efficiency and simultaneous low soot and NOx emissions. Running the engine in PPC mode with high octane number fuels has the advantage of a longer premix period of fuel and air which reduces soot emissions, even at higher loads. The problem is the ignitability at low load and idle operating conditions. The objective is to investigate the use
Background: Although improvements are achieved by general exercise, training to improve sensorimotor control may be needed for people with osteoarthritis (OA). The aim was to apply the principles of neuromuscular training, which have been successfully used in younger and middle-aged patients with knee injuries, to older patients with severe hip or knee OA. We hypothesized that the training program
Interpretations of the church, monastery and manor of Dalby have focused primarily on the history and functions of the buildings, but symbolic interpretations have been involved too. The article discusses four categories of symbolic interpretations: Power Symbols, Cosmic Symbols, Biblical Symbols and Geographical Symbols. The conclusion is that it is hard, when dealing with specific buildings, to
A protocol for the diastereoselective synthesis of C-1 indol-3-yl substituted tetrahydroisoquinoline derivatives via Pictet-Spengler condensation with L-DOPA or L-DOPA derivatives and 1H-indole-3-carbaldehydes is presented. The protocol is used for the successful synthesis of several tetrahydroisoquinolines as well as diketopiperazine fused analogues. (C) 2012 Elsevier Ltd. All rights reserved.
The Camassa-Holm (CH) and Hunter-Saxton (HS) equations have an interpretation as geodesic flow equations on the group of diffeomorphisms, preserving the H-1 and. H-1 right-invariant metrics correspondingly. There is an analogy to the Euler equations in hydrodynamics, which describe geodesic flow for a right-invariant metric on the infinite-dimensional group of diffeomorphisms preserving the volume
Moraxella catarrhalis is a common pathogen found in children with upper respiratory tract infections, and in patients with chronic obstructive pulmonary disease during exacerbations. The bacterial species is often isolated together with Streptococcus pneumoniae and Haemophilus influenzae. Outer membrane vesicles (OMV) are released by M. catarrhalis and contain phospholipids, adhesins, and immunomo
This paper presents a decomposition strategy applicable to DAE constrained optimization problems. A common solution method for such problems is to apply a direct transcription method and solve the re- sulting nonlinear program using an interior-point algorithm. For this approach, the time to solve the linearized KKT system at each iteration typically dominates the total solution time. In our propo
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3 fb(-1) of data collected in proton-proton collisions at root s = 8 TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS
