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Ubiquitous neocortical decoding of tactile input patterns

Whereas functional localization historically has been a key concept in neuroscience, direct neuronal recordings show that input of a particular modality can be recorded well outside its primary receiving areas in the neocortex. Here, we wanted to explore if such spatially unbounded inputs potentially contain any information about the quality of the input received. We utilized a recently introduced

Physiology, Metabolism, and Fossilization of Hot-Spring Filamentous Microbial Mats

The evolutionarily ancient Aquificales bacterium Sulfurihydrogenibium spp. dominates filamentous microbial mat communities in shallow, fast-flowing, and dysoxic hot-spring drainage systems around the world. In the present study, field observations of these fettuccini-like microbial mats at Mammoth Hot Springs in Yellowstone National Park are integrated with geology, geochemistry, hydrology, micros

Behavioral disturbances and pharmacological treatment of patients with dementia in family caregiving : A 2-year follow-up

Behavioral disturbances are common in dementia. Polypharmacy due to progression of disease and fluctuation of symptoms among patients might increase risk of overtreatment and/or undertreatment. Drug prescription habits were studied in relationship to symptoms of dementia after relocation of patients to group-living care units (GC). Seventy-six demented patients (mean age 81 years) were assessed be

Modern technology against falls-The MoTFall project

Background: The strongest risk factor for falls is a history of falls. Therefore, interventions targeting persons at risk of falling before they are aware of the risk themselves is highly demanded. The prevention of falls is a complex task and has no easy solutions; an interdisciplinary approach is necessary. Modern technology provides us with novel opportunities to detect and monitor falls and ne

Interstitial laser thermotherapy : Comparison between bare fibre and sapphire probe

A sapphire probe and a bare fibre were compared with respect to temperature control and distribution and light fluence in interstitial laser thermotherapy. Experiments were performed in processed liver using an Nd-YAG laser and output power levels of 1-4 W. The temperature was controlled at a distance of 10 mm using a feedback circuit with an automatic thermometry system and thermistor probes. Wit

Associations of cigarette smoking with disease phenotype and type I interferon expression in primary Sjögren's syndrome

Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patients filled out the EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) form

In the blind-spot of governance – Stakeholder perceptions on seagrasses to guide the management of an important ecosystem services provider

Seagrass ecosystems have been identified as important marine ecosystem service (ES) providers, they contribute to coastal protection, fisheries provision and mitigate climate change among others. Yet, they are declining globally at alarming rates. While the ecological dimensions of this social-ecological system have been well studied, its associated social aspects remain largely unexplored. Here,

The calcar femorale as a landmark in hip physiolysis

The position of the femoral head in relation to the calcar femorale was analyzed from 120 radiographs of normal hips. A constant relationship was found, providing a method of calculating the normal position of the femoral head. the method was tested in 56 cases with physiolysis of the hip and was found to be useful in determining the degree of slipping in both adolescents and adults.

Smoking habits in patients with inflammatory bowel disease

The proportion of smokers in this study was significantly lower among patients with ulcerative colitis (13%) than among patients with Crohn's disease (47%), the difference being significant for both sexes and for the age groups both below and above 40 years. The proportion of male ex-smokers among patients with ulcerative colitis (28%) was higher than among patients with Crohn's disease (8%), wher

Improved activity retention of enzymes deposited on solid supports

Enzymes deposited on solid support usually show good stability when operated in organic solvents. Decreased stability of the enzyme preparations was noticed when low enzyme loadings were used (e.g., with Celite as support; less than 1 mg enzyme/g). It was possible to avoid the activity loss by the addition of an additive which protects the enzyme during the immobilization. Proteins (such as albumi

Three systems used for biocatalysis in organic solvents a comparative study

The activity and operational stability of horse liver alcohol dehydrogenase (HLADH) and αchymotrypsin were investigated in three systems commonly used for biocatalysis in organic solvents: 1. enzyme adsorbed on a solid support (celite) and added to the organic solvent (isooctane) 2. enzyme powder directly added to the organic solvent (isooctane). 3. enzyme dissolved in a microemulsion (AOT/isoocta

Autogenic bone paste in posterolateral fusion of the lower lumbar spine

In order to facilitate bone graft harvesting and to get more mouldable bone graft in posterolateral fusions of the lower lumbar spine, a modified technique of bone graft harvesting was utilized. Through a midline skin incision the most posterolateral part of an iliac crest was ground with a reamer to a smooth bone paste. The technique was used in lumbar posterolateral fusions without osteosynthesi

Functional activity of intrahippocampal septal grafts is regulated by catecholaminergic host afferents as studied by microdialysis of acetylcholine

Previous microdialysis experiments have shown that acetylcholine (ACh) release from septal grafts in the hippocampus of awake rats is influenced by the behaviour of the animals, which strongly suggests that the host brain can exert a regulatory control over the activity of the grafted neurons. Since the activity of the normal septo-hippocampal cholinergic system is likely to be regulated, in part,