A Path for Improving Stroke Recovery. Effects of MEK-ERK1/2 Inhibition
The present thesis aimed to shed more light on the notion of acute inhibition of extracellular-signal regulated kinase (ERK)1/2 pathway as a treatment to improve stroke recovery. Stroke is a major cause of death and long-term disability worldwide, classified as ischemic or hemorrhagic. In ischemic stroke, interruption of blood flow and deprivation of oxygen and glucose activate death signalling pa