Search results

Insect odorant receptor (OR) genes are routinely expressed in Human Embryonic Kidney (HEK) 293 cells for functional characterization (“de-orphanization”) using transient or stable expression. However, progress in this research field has been hampered because some insect ORs are not functional in this system, which may be due to insufficient protein levels. We investigated whether codon optimizatio

Fetal hemoglobin (HbF) has been developed into an important alternative protein for oxygen therapeutics. Such applications require extensive amounts of proteins, which only can be achieved via recombinant means. However, the expression of vertebrate hemoglobins in heterologous hosts is far from trivial. There are several issues that need to be dealt with. These include, among others, the solubilit

When rain falls on the city, it creates urban runoff that cause flooding, erosion, and water pollution. Municipal engineers manage a complex network of technical and natural systems to treat and remove these temporary water flows from cities as quickly as possible. Urban runoff is frequently discussed in terms of technical expertise and environmental management, but it encompasses a multitude of s

This book explores how the concept or urban experimentation is being used to reshape practices of knowledge production in urban debates about resilience, climate change governance, and socio-technical transitions.With contributions from leading scholars, and case studies from the Global North and South, from small- to large-scale cities, this book suggests that urban experiments offer novel modes

The era of the smart city has arrived. Only a decade ago, the promise of optimising urban services through the widespread application of information and communication technologies was largely a techno-utopian fantasy. Today, smart urbanisation is occurring via urban projects, policies and visions in hundreds of cities around the globe.Inside Smart Cities provides real-world evidence on how local a

Modern cities are often perceived as the antithesis of nature; the built environment is understood as the transformation of raw and untamed nature into a rationalized human landscape. However, a variety of scholars since the nineteenth century have noted the persistence of nature in cities, not only in providing essential services but also resisting human control. Most recently, urban geographers

Preterm birth carries a risk for adverse neurodevelopment. Cognitive dysfunctions, such as language disorders may manifest as atypical sound discrimination already in early infancy. As infant-directed singing has been shown to enhance language acquisition in infants, we examined whether parental singing during skin-to-skin care (kangaroo care) improves speech sound discrimination in preterm infant

PurposeArchitectural theorists have a long tradition of acknowledging the centrality of building users to architectural production. This article contributes to the discourse on architecture, actor–network theory (ANT), and users by proposing a typology of user translations ranging from supporting to tinkering to adjusting to resisting.Design/methodology/approachThe research utilises an ANT-inspire

Purpose: Institutional and commercial web profiles that provide biobibliographic information about researchers are used for promotional purposes but also as information sources. In the latter case, the profiles' (re)presentations of researchers may be used to assess whether a researcher can be trusted. The article introduces a conceptual framework of how trust in researchers may be formed based on

Introduction and aim: Air pollution, a major environmental threat to human health, contributes to the premature deaths of millions of people worldwide. Cooking with solid fuels, such as charcoal and wood, in low-and middle-income countries generates very high emissions of particulate matter within and near the household as a result of their inefficient combustion. Women are especially exposed, as

Purpose Total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) are both considered suitable for antero-medial osteoarthritis and spontaneous osteonecrosis of the knee. National registry data are consistent in showing higher revision rates for UKA. Adequately adjusted, these findings may be challenged by differences in adverse events and patient-reported outcomes, as both can ha

"This new edition of Lund and Learning paints a picture of Lund as a city of learning, from the age of the medieval bishops to the university reforms of the 1990s."

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

Due to a general expansion of Swedish public sector in the 1960s and 70s, there was a perceived need not only for closer contact between citizens and government agencies, but also for more government information about citizens’ rights and responsibilities. Following a government report called Expanded Government Information (1969), where a modernized and more active form of government information

During World War II, both Nazi Germany and the Allies invested heavily in propaganda in neutral Sweden. The battle for hearts and minds did not only involve widespread dissemination of propaganda, but Stockholm became a veritable hotspot for espionage as well as intelligence gathering on enemies’ propaganda efforts. Moreover, throughout the war, the Allies used Sweden as a key gateway to circulate

Transitions from one socio-technical regime configuration to another entail long phases of institutional complexity, where two or more field logics co-exist in a sector and induce incompatibilities and frictions. This paper presents a dynamic phase model, which characterizes the types of institutional complexity that may build up and settle across various phases of a transition, illustrated with a

We systematically investigate the complexity of counting subgraph patterns modulo fixed integers. For example, it is known that the parity of the number of k-matchings can be determined in polynomial time by a simple reduction to the determinant. We generalize this to an nf(t,s)-time algorithm to compute modulo 2t the number of subgraph occurrences of patterns that are s vertices away from being m