Search results

Filter

Filetype

Your search for "*" yielded 529296 hits

Design and implementation of reciprocal unit

This paper presents the design and implementation of a reciprocal unit, in which the initial approximation of the reciprocal is obtained using a look-up table and a multiplication. How to create a look-up Table efficiently is described in detail, and the error analysis for the ROMs of different sizes is also given in this paper. The presented design utilizes a 27

Toward an enzyme-based oxygen scavenging laminate. Influence of industrial lamination conditions on the performance of glucose oxidase

The laminate consisted of several polymer layers, aluminium, and one cellulose-based layer containing the active enzymatic system (e.g., glucose oxidase, catalase, glucose, and CaCO3). During the industrial lamination process, the enzyme layer was exposed to three temperature spikes up to 325degreesC without significant enzyme inactivation. Ninety-seven percent of the glucose oxidase activity stil

Association between adducin-1 G460W variant and blood pressure in Swedes is dependent on interaction with body mass index and gender.

Background: The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body mass index (BMI), or age. Methods: The G460W polymorphism was genotyped in the p

The 5 ' Region of the MSH2 gene involved in hereditary non-polyposis colorectal cancer contains a high density of recombinogenic sequences

MSH2 rearrangements are involved in approximately 10% of hereditary non,polyposis colorectal cancer (HNPCC) families, and in most of the rearrangements, exon I is deleted. We scanned by quantitative multiplex polymerase chain reaction (PCR) of short fluorescent fragments (QMPSF) 200 kb of genomic sequences upstream of the MSH2 transcription initiation site in 21 HNPCC families with exon I deletion

The environmental determinants of diabetes in the young (TEDDY) study: Study design

The primary objective of this multicenter, multinational, epidemiological study is the identification of infectious agents, dietary factors, or other environmental exposures that are associated with increased risk of autoimmunity and type 1 diabetes mellitus (T1DM). Factors affecting specific phenotypic manifestations such as early age of onset or rate of progression or with protection from the de

The stratigraphy of the Upper Ordovician carbonate mounds in the subsurface of Gotland

In a revision of the stratigraphic classification of the subsurface Upper Ordovician succession of Gotland, the terms Lower and Upper Ostersjo Limestone are rejected and replaced by the Slandrom Limestone and the File Limestone, respectively. Two mound generations are recognized, the Rakveran-Nabalan Liste mounds and the Pirguan Klasen mounds, the latter being by far the most common. Both occur no

Forecasting near-surface ocean winds with Kalman filter techniques

In this paper a statistical forecasting model designed for bounded areas of near-surface ocean wind speeds is implemented. Dimension reduction is achieved by decomposing the covariance structure into one large-scale and one small-scale component using empirical orthogonal functions. The large-scale component is modelled with an AR process and forecasts are calculated by applying a Kalman filter. T

Consistent sex ratio bias of individual female dragon lizards

Sex ratio evolution relies on genetic variation in either the phenotypic traits that influence sex ratios or sex-determining mechanisms. However, consistent variation among females in offspring sex ratio is rarely investigated. Here, we show that female painted dragons (Ctenophorus pictus) have highly repeatable sex ratios among clutches within years. A consistent effect of female identity could r

Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants

The important issue addressed by the studies presented here is the mechanism of neutrophil-mediated damage to endothelial and epithelial cells during inflammation. Binding of neutrophil-released granule proteins to endothelial cells may be involved in vascular damage in patients with inflammatory vascular diseases. We have determined whether granule proteins proteinase 3(PR3) and/or myeloperoxidas

On the limited operational lifetime of light-emitting electrochemical cells

Light-emitting electrochemical cells offer efficient light-emission but suffer from short operational lifetimes. The latter is demonstrated to stem from photoinduced chemical reactions involving the conjugated polymer in the light-emitting p-n junction region, as evidenced by, e.g., optical and Raman microscopy (see figure). It is possible to alleviate the extent of these side reactions, and accor

Proliferative synovitis in rabbit knee joints induced by antigen and preformed immune complexes

Knee joints of non-immunized rabbits were repeatedly injected with bovine serum albumin (BSA) and preformed BSA-anti-BSA immune complexes which had differing precipitation profiles and abilities to activate complement. Ten days after the last of six injections the antibody and lymphoproliferative responses to BSA were analysed and correlated to the degree of arthritis. Joint swelling, increased nu

Location of interstitial cells and neurotransmitters in the mouse bladder

To investigate whether interstitial cells (ICs) are present in the adult mouse bladder, and what transmitters characterize adjacent nerve fibres, as ICs in human and guinea-pig bladder lie close to nerve fibres but transmitters present in these nerves have not yet been reported. Sections of the bladder wall from 12 adult male mice (six each, aged 3-4 or 18-24 months) were incubated in carboxygenat

Umbilical Cord Levels of Interleukin-1 Receptor Antagonist and Neonatal Outcome.

Background: Previous studies indicate that there may be infant gender differences in cytokine expression associated with differences in neonatal morbidity. Objective: We tested the hypothesis that umbilical cord interleukin-1 receptor antagonist (IL-1ra) correlates with infant gender and neonatal outcome in preterm infants. Study Design: IL-1ra was measured in cord blood taken from 58 preterm infa

Abnormal DNA synthesis in polyamine deficient cells revealed by bromodeoxyuridine-flow cytometry technique

Chinese hamster ovary cells were seeded in the absence or presence of the polyamine synthesis inhibitor 2-difluoromethylornithine (DFMO). At 1-4 days after seeding, the cells were labelled for 15-120 min with the thymidine analogue bromodeoxyuridine (BrdUrd) and they were then fixed directly after the labelling period. In addition, cells were labelled for 30 min and they were then allowed to progr

Occupational status, educational level, and the prevalence of carotid atherosclerosis in a general population sample of middle-aged Swedish men and women: results from the Malmo Diet and Cancer Study

The associations among educational level, occupational status, and atherosclerosis were investigated during 1992-1994 in a general population sample of 4,176 Swedish men and women. Carotid artery intima-media thickness (IMT) and carotid stenosis were determined by B-mode ultrasound. Socioeconomic differences in mean carotid IMT and odds ratios for carotid stenosis prevalence were estimated. In wom

Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.

One of the major quantitative trait loci (QTLs) associated with arthritis in crosses between B10.RIII and RIIIS/J mice is the Cia5 on chromosome 3. Early in the congenic mapping process it was clear that the locus was complex, consisting of several subloci with small effects. Therefore, we developed two novel strategies to dissect a QTL: the partial advanced intercross (PAI) strategy, with which w

Visual femininity and masculinity in synthetic characters and patterns of affect

It has been shown that users of a digital system perceive a more ‘masculine-sounding’ female voice as more persuasive and intelligent than a corresponding but more ‘feminine-sounding’ female voice. Our study explores whether a parallel pattern of affectively colored evaluations can be elicited when femininity and masculinity are manipulated via visual cues instead of via voice. 80 participants enc

PFG-NMR diffusometry: A tool for investigating the structure and dynamics of noncommercial purified pig gastric mucin in a wide range of concentrations

For the first time, Pulsed Field Gradient-Nuclear Magnetic Resonance, a powerful noninvasive tool for studying the dynamics and structure of complex-gels, has been used to measure diffusion of probe molecules in aqueous solutions/gels of noncommercial purified pig gastric mucin (PGM), in a concentration range up to 5 wt%. Complementary data were obtained from rheology measurements. The combination