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There is a need for harmonisation of stability study designs of monoclonal antibodies. Monoclonal antibodies (mAbs) are widely used in treatments for various diseases. Like all drugs, their quality must be verified through stability studies. The ICH guidelines give general recommendations regarding stability studies of antibodies, and specifications should often be determined on a case-by-case bas
Syftet med examensarbetet har varit att utveckla och utvärdera ett realtidssystem som utför analys i molnet och lokalt med hjälp av AWS. De viktigaste målen har varit att skapa ett system som är så snabbt som möjligt och att analysera vilken del av analysen som kan göras i molnet och vilken del som måste göras lokalt. Den förväntade nyttan med systemet är de minskade utvecklings- och underhållskosThe purpose of the degree project has been to develop and evaluate a real-time analysis system which performs analysis in the cloud and locally using AWS. The most important goals have been to create a system which is as fast as possible and to reflect over which part of the analysis can be made in the cloud and which part has to be made local. The expected utility of the system is a consequence o
For individuals with gender dysphoria, voice therapy can be an important tool to change characteristics about their voice to align better with their gender identity. This is often done by practising with a speech therapist and can be a long and difficult process. A useful tool in this setting would be software that can generate a voice, based on the patients voice, which lies slightly closer to th
This thesis investigated the phenomenon of pupils’ transportation in Abu Dhabi and studied the relationship between their transportation, stress levels, and school performance. This study combined standard and geospatial statistical tools with a quantitative survey of 982 grade 6 to grade 9 students from 40 classrooms of 17 public and private schools in Abu Dhabi Island. The thesis tested five hyp
Syftet med uppsatsen var att undersöka utgivningen av svensk fantasy och science fiction för att försöka ta reda på hur genrernas spridning ser ut i Sverige. Undersökningen rörde utgivningen under femårsperioden 2015-2019. Vidare undersöktes ett antal bokomslag för att se hur typen av förlag påverkar utformningen när det kommer till kvalitet och genrekännedom. Analysen av utgivningen är en kvantit
Humanitarian crises caused by natural disasters or human reasons have hampered the access of generations of young adults to higher education. The aftermath of the Syrian conflict in 2011 led to the emergence of various initiatives, mostly set in neighboring countries and the global north, for refugees and displaced populations to pursue higher education studies. Policymakers and academics have foc
Bakgrund: Rökning är ett stort hot mot folkhälsan. Det saknas effektiva hjälpmedel. Denna studie undersökte effekten av öronakupressur och aurikuloterapi vid rökavvänjning. Metod: En systematisk litteraturstudie. Sökningar i sex databaser identifierade åtta randomiserade kontrollerade studier (1232 deltagare). Metodologisk kvalitet bedömdes genom att använda SBU:s granskningsmall för RCT-studier. Background: This systematic review examined the effects of ear acupressure and auriculotherapy for cigarette smoking cessation (SC). Methods: Searches in six databases located eight randomized controlled trials (1232 participants). Methodological quality was assessed using the SBU review template for RCT studies. Results of included articles were synthesized using narrative analysis. Results: Stud
Traumatic brain injury (TBI) is a common cause of morbidity and mortality in young individuals. Following TBI, the initial injury caused by the head impact is exacerbated by a complex cascade of secondary injury factors leading to increased tissue loss. TBI is an established risk factor for neurodegenerative disorders including Alzheimer disease (AD). In long-term survivors of TBI, increased aggre
The debt to disposable income ratio of Swedish households has the past thirty years increased radically and mortgages cover eighty percent of household’s financial liabilities. According to the Life-cycle hypothesis, households maintain a steady consumption throughout their lifetime by accumulating mortgages in early ages with the aim to repay their debts when their economy becomes stronger as the
Tekniker från maskininlärning används för att undersöka grundvatten i Sverige. I den första delen av uppsatsen används artificiella neuronnätverk och beslutsträd för att förutsäga hur hög grundvattennivån kommer vara i en brunn om en månad. För att göra detta används tidigare grundvattennivåer i brunnen och i andra närliggande brunnar. Historisk data över temperatur och nederbörd används också. I We apply neural networks and random forest to study geological data. In part one of the thesis, a ground water level prediction task is performed with recurrent neural networks, random forest and vector autoregression. The input data consists of weather data and other ground water level time series. The MAE and R-squared is evaluated and the variation in performance of the neural networks is discu
BIM, Byggnads Informations Modell, samordning, digitalisering, byggnad, anläggning, effektivering, beställarkrav
Abstract Purpose: To examine how flagship stores might affect brand equity for brands in the fastmoving consumer goods industry. Methodology: This paper adopts a qualitative research method. The information about the two cases on the flagship stores of Swedish Match and Löfbergs was collected by observations at the physical flagship stores and secondary data from the brands web pages. Furthermore,
This thesis analyzed multimodal social media communications of a government agency that manages national parks, to study the kinds of discourses that are constructed by national parks agencies through representations of the parks and their nature. Furthermore, it analyzed and interpreted how the discourses relate to the mandate and other missions that the agency must adhere to, which are generally
Studien undersöker hur gymnasieelever på estetiskt program musik upplever sin ensembleundervisning ur ett genusperspektiv kopplat till platstagande, huvudinstrument och kön. Eftersom pop/rock-genren dominerar såväl musikundervisning i grupp som ensemblegrupperna har perspektiv kring hur genus står i relation till populärmusik implementerats i studien. Syftet med studien är att undersöka vilka faktThe study examines students’ conception of ensemble class at Arts Program/Music (ES) in upper secondary school in Sweden from a gender perspective, such as sex connected to choice of instrument and claiming space, linked to learning limitations and opportunities. The pop / rock genre dominates music education in Sweden (Skolverket, 2015), like the ensemble groups I have studied, hence perspectives
År 2015 antog FN:s länder en agenda för hållbar utveckling som idag kallas för Agenda 2030. Agendan omfattar 17 globala mål samt 169 delmål som skapades för att världen över kunna uppnå en ekonomisk, social samt ekologisk hållbarhet. Dessa mål bygger på millenniemålen där syftet är att slutföra det som inte uppnåddes. Begreppet hållbarhet kan definieras på olika sätt och kan därmed uppfattas olikaIn 2015, the UN countries adopted an agenda for sustainable development, it is today called the 2030 Agenda. The agenda includes 17 global goals and 169 targets that were created to achieve economic, social and ecological sustainability worldwide. These goals are based on the Millennium Development Goals, the purpose of which is to complete what was not achieved. The concept of sustainability can
Methane is a potent greenhouse gas that plays a major role in climate change. Significant uncertainty exists in the estimates of emissions from natural methane sources. This uncertainty in data is one of the primary scientific challenges in climate model. Geological seepage considered as the second largest natural source of methane after wetlands and today is recognized as a major contributor to a
The genre of Swedish versified offices from the Middle Ages has been utterly unnoticed, despite the great value it bears to research in a number of fields. This is a critical text edition and a musicological edition of the anonymously written Swedish versified office "Stabat Virgo dolorosa", for the feast "Compassio Marie". It is thought to have been composed around 1400 in or
I en enda droppe vatten från Öresund finns det ungefär 25 000 bakterier, vilket resulterar i att man kan få i sig en hel del bakterier när man badar i havet, speciellt barn och hundar som inte är så duktiga på att hålla munnen stängd vid bad. Lyckligtvis är de allra flesta av dessa bakterier goda som inte skadar dig men om du haft oturen att bada i vatten med dålig kvalitet kan du bli sjuk av exemThis master thesis has investigated if flow cytometry can be used to monitor bathing water quality on the beaches in Southern Sweden. The current method for monitoring the bathing water quality takes 3 days to get results about the concentrations of fecal indicator bacteria, E.coli and intestinal enterococci, and to get answers if the water is usable or unusable for swimming. These bacteria serve
