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The diagnosis of Parkinsonian disorders is currently based on clinical criteria, which have limited sensitivity until most dopaminergic neurons are lost. Here we show that cerebrospinal fluid levels of DOPA decarboxylase (DDC) (also known as aromatic L-amino acid decarboxylase) can accurately identify patients with Lewy body disease (LBD) (area under the curve (AUC) = 0.89; PFDR = 2.6 × 10-13) and

With the introduction of information theory in the middle of the 20th century, the concept of noise came to be contrasted with signal. The exhibition Noise to Signal mainly consists of two projects that highlight the relative nature of these terms.The three textile works, all with the title Untitled (Noise), appear abstract but also represent a grainy filter that is usually applied to digital imag

This study investigates the relationship between changes in the frequency of dwell time delays and passenger flow characteristics and the frequency of railway service during the COVID-19 pandemic. To do so we make use of automatic passenger count data from commuter trains in Southern Sweden. Our findings show that the frequency of dwell time delays decreased under COVID-19 conditions compared to t

As the effects of climate change, political upheaval and ravaging war are palpable, apocalyptic images as well as the concept ‘apocalyptic’ are today regularly invoked in politics, popular culture and mass media. This essay ponders the potential dangers of the apocalyptic imaginary, especially its tendency to encourage idealization of one’s own community and demonization of the other. As carriers

THE LITTLE STINT Calidris minuta is an Arctic wader species that migrates through the Baltic Sea region towards wintering areas in North and West Africa and the Mediterranean region. We use a 75-year trapping series, comprising 4,791 Little Stints on autumn migration, from Ottenby Bird Observatory in Sweden to illustrate long-term trends in abundance, phenology, and morphometrics. Numbers of trapp

In order to rationally allocate multi-path component (MPC) of wireless channels to different clusters, a multi-path clustering algorithm based on Bisecting K-means clustering was proposed for millimeter-wave channels to solve the problem of partial optimization of traditional K-means clustering methods. The MPC clustering was implemented based on the cluster split and iteration computation strateg

This paper addresses one of the pedagogical challenges that followed the presence of increasingly multinational student groups, particularly the increased diversity of academic backgrounds among students. Theoretically, this challenge can be understood as an encounter between different teaching and learning regimes (TLRs). TLR, coined by Trowler and Cooper (2002), implies a constellation of assump

Context: In the contemporary body of software engineering literature, some recurrent shortcomings characterize how threats to validity (TTV) are considered in studies. Objective: With this position paper, we aim to open a discourse on the current use of TTV sections. The goal of our position is to jointly reflect and systematically improve how we, as a research community, consider TTV in our studi

Objective: Using Swedish nationwide registry data, we investigated the contribution of genetic and environmental risk factors to the etiology of alcohol use disorder (AUD) by extended twin pedigree modeling. Method: AUD was defined using public inpatient, outpatient, prescription, and criminal records. Three-generational pedigrees were selected for index individuals born between 1980 and 1990, obt

Assertions are one of the most useful automated techniques for checking program’s behaviour and hence have been used for different verification and validation tasks. We provide an overview of the last two decades of research involving ‘assertions’ in software testing. Based on a term–based search, we filtered the inclusion of relevant papers and synthesised them w.r.t. the problem addressed, the s

Artikel i Nationalencyklopedin

The Swedish Armed Forces (SwAF) air dive tables are under revision. Currently, the air dive table from the U.S. Navy (USN) Diving Manual (DM) Rev. 6 is used with an msw-to-fsw conversion. Since 2017, the USN has been diving according to USN DM rev. 7, which incorporates updated air dive tables derived from the Thalmann Exponential Linear Decompression Algorithm (EL-DCM) with VVAL79 parameters. The

Objectives: To conduct the first-ever nationwide, population-based cohort study investigating survival patterns of all patients with incident SSc in Sweden compared with matched individuals from the Swedish general population. Methods: We used the National Patient Register to identify patients with incident SSc diagnosed between 2004 and 2015 and the Total Population Register to identify comparato

The scanning photoelectron microscope (SPEM), developed more than 30 years ago, has undergone numerous technical developments, providing an incredibly vast kind of feasible sample environments, which span from the traditional high spatial resolution core level based chemical analysis to insitu and operando complex experiments, including also electrochemical setups and operational electronic device

BACKGROUND/PURPOSE: Intraductal papillary neoplasm of the bile duct (IPNB) is a rare disease in Western countries. The main aim of this study was to characterize current surgical strategies and outcomes in the mainly European participating centers. METHODS: A multi-institutional retrospective series of patients with a diagnosis of IPNB undergoing surgery between 1 January 2010 and 31 December 2020

In this article, hesitancy towards COVID-19 vaccinations is investigated as a phenomenon touching upon existential questions. We argue that it encompasses ideas of illness and health, and also of dying and fear of suffering. Building on a specific strand within anti-vaccination studies, we conjecture that vaccine hesitancy is, to some extent, reasonable, and that this scepticism should be studied

Migrant workers, both regular and irregular, are at particular risk of having their rights violated. At the same time, there has been an absence of support for exploited immigrant workers from Swedish authorities and civil society. Lately, a number of trade unions and semi-union organisations in Sweden have developed methods to mobilize the rights of migrant workers experiencing exploitation on th

Nasopharyngeal cancer (NPC) is a malignant tumor. In a recent publication, we described the presence and distribution of CD8+ T cells in NPC and used the information to identify ‘inflamed’, ‘immune-excluded’, and ‘desert’ immune phenotypes, where ‘inflamed’ and ‘immune-excluded’ NPCs were correlated with CD8 T cell infiltration and survival. Arguably, more detailed and, in particular, spatially re