OBJECTIVE: The gut microbiota is increasingly being implicated in cardiovascular health. Metabolites produced by bacteria have been suggested to be mediators in the bacterial action on cardiovascular health. We aimed to identify gut microbiota-related plasma metabolites and test whether these metabolites associate with future risk of coronary artery disease (CAD). METHODS: Nontargeted metabolomics

Recent studies have highlighted that oscillatory and time-dependent shear flows might help increase the flowability of dense suspensions. While most focus has been on cross-flows we here study a simple two-dimensional suspensions where we apply simultaneously oscillatory and stationary shear along the same direction. We first show that the dissipative viscosities in this set-up significantly decre

Background: Diseases of the bowel are not always displayed on conventional abdominal computed tomography (CT). The studied oral contrast agent aims to improve this. Purpose: To investigate whether the use of a novel oral contrast for abdominal CT enables the same diagnostic advantages as seen in magnetic resonance imaging (MRI). Material and Methods: Twenty-five consented volunteers drank up to 14

Previous research demonstrates that conflict framing in news articles can influence individuals’ attention, selection, and distribution of news. However, no study has examined whether the valence of social media comment fields can trigger similar effects for news engagement on Facebook. In this mixed-methods study, we combine eye tracking with surveys, and conduct an experiment in which participan

Purpose: The purpose is to explore the different and often contradictory perceptions individual managers have about corporate sustainability within a global retailer. Design/methodology/approach: A qualitative case study method is used, including interviews and document studies. The authors study the global retailer IKEA. In total the authors have interviewed respondents on both the global level a

This book comprises the select proceedings of the International Conference on Future Learning Aspects of Mechanical Engineering (FLAME 2020). This volume focuses on current research in fluid and thermal engineering and covers topics such as heat transfer enhancement and heat transfer equipment, heat transfer in nuclear applications, microscale and nanoscale transport, multiphase transport and phas

The electronic band structure of complex nanostructured semiconductors has a considerable effect on the final electronic and optical properties of the material and, ultimately, on the functionality of the devices incorporating them. Valence electron energy-loss spectroscopy (VEELS) in the transmission electron microscope (TEM) provides the possibility of measuring this property of semiconductors w

We engineer a system of two strongly confined quantum dots to gain reproducible electrostatic control of the even-electron spin at zero magnetic field. Coupling the dots in a tight ring-shaped potential with two tunnel barriers, we demonstrate that an electric field can switch the electron ground state between a singlet and a triplet configuration. Comparing our experimental cotunneling spectrosco

OBJECTIVE: While existing evidence supports beneficial cardiovascular effects of glucagon-like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic peptide (GIP) and/or signaling via the GIP receptor may have untoward cardiovascular effects. Indeed, recent studies show that fasting physiological GIP levels are associated with total mortality and cardiovascular mortalit

Gasparyan sketches a semiotic theory where world, mind and language – the latter a stand-in for all semiosis – collapse into one “recursive” whole. In contrast, cognitive semiotics differentiates life-world from subject and perception from signification, as well as between different semiotic systems, of which language is only one. Handling Editor • Alexander Riegler.

The Kingdom of Crystal, an area in southern Sweden famous for its many glassworks, is historically heavily burdened by pollution from this industry. Glass crust containing cadmium (Cd), lead (Pb), and arsenic (As) has been deposited around the area and used as filling. The purpose of this study was to monitor whether the high levels of metals in the contaminated soil were reflected in blood and ur

We previously reported that loss of mitochondrial transcription factor B1 (TFB1M) leads to mitochondrial dysfunction and is involved in the pathogenesis of type 2 diabetes (T2D). Whether defects in ribosomal processing impact mitochondrial function and could play a pathogenetic role in β-cells and T2D is not known. To this end, we explored expression and the functional role of dimethyladenosine tr