Search results

Filter

Filetype

Your search for "*" yielded 540348 hits

A comprehensive review of Schisandra chinensis lignans : pharmacokinetics, pharmacological mechanisms, and future prospects in disease prevention and treatment

Lignans derived from Schisandra chinensis have attracted significant attention for their diverse pharmacological activities and clinical potential. This review presents a comprehensive analysis of the pharmacological properties of Schisandra chinensis lignans, including their antioxidant, anti-inflammatory, neuroprotective, hepatoprotective, antibacterial/viral, antidiabetic and anticancer effects

Self-supervised representation learning for geospatial objects : A survey

The proliferation of various data sources in urban and territorial environments has significantly facilitated the development of geospatial artificial intelligence (GeoAI) across a wide range of geospatial applications. However, geospatial data, which is inherently linked to geospatial objects, often exhibits data heterogeneity that necessitates specialized fusion and representation strategies whi

Perivascular macrophages in the central nervous system : insights into their roles in health and disease

Perivascular macrophages (PVMs) are a specialized subset of macrophages situated near blood vessels in the brain. Their strategic positioning around these vessels enables them to perform key functions in immune surveillance and response to inflammation and injury. These cells are crucial for modulating the immune response within the brain, contributing to normal central nervous system (CNS) proces

Communication aspects of feedback from workers’ health surveillance due to hand-arm vibration exposure − a scoping review

Background: The feedback of the surveillance results to the employee and the employer largely determines the impact of workers’ health surveillance on workers’ health and exposure. We are unaware of any guidebooks or articles on performing feedback on regulated workers’ health surveillance, e.g., for vibration-exposed workers. Objectives: To identify existing knowledge of the communication aspects

Case study on challenges in research with public partners : A personal data incident during recruitment for a survey study on ageing and housing

Objective: To highlight experiences from a personal data incident, which occurred during recruitment for a project focused on how housing choices and relocation are related to active and healthy ageing. Results: Based on established collaboration, the researchers and representatives of housing companies planned for recruitment. Invitations to participate was distributed to persons registered with

An echo state network for synthesizing the standard 12-lead ECG from a two-lead ECG obtained from a single touch of a wrist-worn device

Background: With the availability of a wrist-worn device capable of acquiring two ECG leads with a single touch, synthesis of the 12-lead ECG may be accomplished to facilitate clinical interpretation. Objective: This study proposes an echo state network (ESN) for synthesizing the 12-lead ECG from two leads simultaneously acquired using a wrist-worn device. Methods: The wrist-worn device, equipped

Weather warning archives reveal spatio-temporal hot spots of compound natural hazards

Individual natural hazards may be combined in different ways, leading to cascading or co-occurring effects, turning them into compound hazards. However, assessment of individual as well as compound hazards is often hampered by short or incomplete observational records of actual hazards, and records of various hazards that do not easily combine. In this study we propose an alternative way to detect

Association between a mobile team intervention in Swedish municipal home care and the effect on emergency department visits and hospitalizations among older adults

Background: Elderly individuals with chronic conditions or acute illnesses are major drivers of hospitalization, with frail patients frequently utilizing emergency department (ED) services. To ease this burden, many countries offer home-based medical services. In Region Halland, Sweden, a mobile team intervention in municipal home care (MHC) was introduced to support frail elderly patients. This s

Six propositions for care-centric planning and governance that promote sustainable cities

This Perspective suggests six conceptual propositions to advance care-centric planning and governance in support of SDG 11. By prioritizing relationships, responsiveness, and collective well-being, while also integrating empowerment, environmental stewardship, and cultural diversity, a care-centric approach fosters more inclusive and sustainable cities. Drawing on selected practice-based examples,

Testing the utility of GPT for title and abstract screening in environmental systematic evidence synthesis

In this paper we show that OpenAI’s Large Language Model (LLM) GPT perform remarkably well when used for title and abstract eligibility screening of scientific articles and within a (systematic) literature review workflow. We evaluated GPT on screening data from a systematic review study on electric vehicle charging infrastructure demand with almost 12,000 records using the same eligibility criter

A process-based life cycle assessment of the climate impact of a Swedish intensive care unit

About 4.4% of the global emissions of greenhouse gases can be ascribed to healthcare. Intensive care is among the most resource intensive specialties and the purpose of this study was to quantify the total climate impact of a Swedish intensive care unit (ICU) and identify modifiable elements that can lower the intensive care unit’s climate impact. A process-based life cycle assessment was conducte

Clinical, genetic, and sociodemographic predictors of symptom severity after internet-delivered cognitive behavioural therapy for depression and anxiety

Background: Internet-delivered cognitive behavioural therapy (ICBT) is an effective and accessible treatment for mild to moderate depression and anxiety disorders. However, up to 50% of patients do not achieve sufficient symptom relief. Identifying patient characteristics predictive of higher post-treatment symptom severity is crucial for devising personalized interventions to avoid treatment fail

Characteristics of children with ataxic cerebral palsy

Background: To compare the characteristics, functional levels, and comorbidities of children with ataxic cerebral palsy (CP), with those of children with other CP subtypes. Methods: A cross-sectional study of children with CP born between 2000 and 2019 as reported in the Scandinavian national CP follow-up programmes and quality registries. Data for age, sex, levels of the Gross Motor Function Clas

The LEADING guideline : Reporting standards for expert panel, best-estimate diagnosis, and longitudinal expert all data (LEAD) methods

Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called the Expert Panel method in medicine, and the Best-Es

Unveiling uncertainties in soil organic carbon modeling : the critical role of climate response functions

Accurately simulating soil organic carbon (SOC) dynamics is essential for carbon-related assessments. Process-oriented SOC models employ temperature (f(T)) and soil moisture (f(W)) response functions derived from specific conditions to simulate SOC responses to climate change, yet are widely applied in regional and global-scale studies. How these functions affect regional SOC simulations remains u

Delivery of Ulva rigida extract by bicontinuous cubic lipid nanoplatforms for potential photodynamic therapy against pancreatic cancer

Ulva rigida is a widely available marine algae representing a valuable biomass from which natural photosensitizers (chlorophylls) can be obtained in an environmentally friendly manner using a green microwave-assisted extraction technique. If properly loaded in biocompatible nanoformulations, such highly hydrophobic chlorophylls with photosensitizing activity may constitute effective drugs useful i

pre-SUCCECS : Lessons learned from implementing resuscitation and stabilisation with an intact cord during caesarean sections – Focus group discussions with implementation teams

Objective: The primary aim of this study was to explore the lessons learned from implementing a procedure of resuscitation and stabilization with an intact umbilical cord for preterm and term infants requiring resuscitation or stabilization during emergency caesarean sections. Methods: Data were collected by two focus group discussions and one individual interview. Participants were members of imp

How Delayed Cord Clamping Saves Newborn Lives

Interest in the subject of umbilical cord clamping is long-standing. New evidence reveals that placental transfusion, facilitated by delayed cord clamping (DCC), reduces death and need for blood transfusions for preterm infants without evidence of harm. Even a brief delay in clamping the cord shows improved survival and well-being, but waiting at least two minutes is even better. We propose that t

Moral distress among maternity and neonatal healthcare workers during the COVID-19 pandemic in Sweden : Results from the COPE staff longitudinal cohort study

Introduction: Moral distress arises when healthcare workers face difficult decisions without adequate information and/or when patient care is compromised due to limited resources, communication issues, or altered work routines in exceptional circumstances. While moral distress in maternity and neonatal healthcare workers (MNHCWs) has been noted, its prevalence, intensity, and impact on well-being

Marketing the past : a literature review and future directions for researching retro, heritage, nostalgia, and vintage

Over the last decades, marketing literature has persistently been interested in how marketers and consumers alike engage with the past through past-themed brands, products, and services. However, our knowledge on past-themed marketing is scattered and treated in largely separated literature streams on retro, heritage, nostalgia, and vintage. This article reviews marketing literature on retro, heri