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Investigating the relationship between normal Neural crest and tumor development

Can normal development help us understand tumor initiation? The field of developmental biology studies the complex processes by which organisms grow. Embryology is one of its subfields and investigates how organisms develop from the moment the egg is fertilized to the later embryonic stages. Embryonic development can sometimes be abnormal and lead to cancer formation. In higher animals, followi

Un mundo donde quepan muchos mundos - en studie om akademins roll som en kunskapskapande samt kunskapslegitimerande institution ur ett dekolonialt perspektiv

I denna uppsats har jag intervjuat sex akademiker för att förstå hur akademin kan förstås ur ett dekolonialt perspektiv samt vilka möjligheter det finns för att arbeta dekolonialt inom akademin. Till hjälp har jag tagit teorier om bankundervisning, nollpunktens hybris, avlänkning, epistemisk våld samt dekoloniala pedagogier. Studien visar att akademin setts som en neutral och fristående institutioWithin the framework for this essay I have interviewed six academics to attain the understanding of how academia can be viewed from a decolonial perspective as well as understand what possibilities exist for working de-colonially within academia. To assist I have used theories on banking education, The hubris of the zero point, delinking, epistemic violence and decolonial pedagogies. The study sho

Konkurrens och digitalisering - En kritisk granskning av EU:s konkurrensrättspolicy i den digitala eran

Digitaliseringen har revolutionerat våra samhällen. Hur vi kommunicerar och interagerar med varandra och hur vi handlar produkter och tjänster har över de senaste åren varit föremål för drastiska förändringar. Bakom dessa förändringar står ett fåtal digitala jättar. Trots att förändringarna har ökat konsumentvälfärden och i regel varit positiva, har farhågor lyfts. Detta har inte minst uppmärksammDigitalization has revolutionized our societies. How we communicate and interact with one another and how we purchase goods and services has changed drastically. A select few technological giants are the driving force behind these changes. Despite the increase in consumer welfare and the overall heightened standard of living, concerns have been raised, especially within the discourse of competitio

Carbon negative textiles issued from marine materials

Marine materials are a potential new raw source for the production of organic and vegan leather and cushioning materials. Being a carbon sink, seaweed and marine plants like seagrass and seaweed farming activity could have a crucial role in the current environmental crisis for the absorption of carbon dioxide in the atmosphere. Products extracted from brown and red seaweed can be used for the prod

Accelerating MCR-ALS decomposition of hyperspectral images using k-means clustering

Att analysera livets biokemi, kemin bakom biologiska processer, är viktigt för att få en förståelse av livets mekanismer, speciellt för små längdskalor. Biokemin hos olika typer av celler skiljer sig åt, vilket kan användas för att t.ex skilja mellan elakartade och icke-elakartade tumörer. Vilka ämnen som finns i en cell kan bli identifierade via deras respektive absorptionspektrum. Ett absorptionA hyperspectral image may be decomposed into component spectra and their distri- bution in the image to simplify analysis by revealing underlying patterns and reducing the dimensionality of the image; this may be achieved by the algorithm MCR-ALS. However, the algorithm is time consuming, but could be accelerated by a data re- duction. Data reduction can be done by using a clustering method. In th

Investigation of endoplasmic reticulum stress in response to hypoxia in lung fibroblasts

Lack of oxygen delivery to the cells results in excessive production of oxygen free radicals in the cells leading to a pathological condition postulated as hypoxia. One of the most crucial transcription factors that can adapt to the fluctuating levels of hypoxia is Hypoxia Inducible Factor-1α (HIF-1α). Chronic obstructive pulmonary disease (COPD) is amongst the common lung diseases majorly caused

Assessing the Impact of Acute Rotavirus Infection on Inflammatory Bowel Disease in a Mouse Model of DSS Colitis

Kan virus skydda oss från tarminflammation? En generell uppfattning är virus gör oss sjuka, men faktum är att vår tarm alltid är fylld av biljontals mikroorganismer, allt från bakterier till virus och svamp. Hur kommer det sig då att vi inte är konstant sjuka? Anledningen är att vi lever i symbios med mikroorganismerna. En störning i denna balans kan göra oss sjuka, det kan till och med resulteraIn recent time the prevalence of inflammatory bowel diseases (IBDs) has increased, especially in developed countries. In these diseases the gut homeostasis is disturbed due to multiple factors such as the hosts own immune system, environmental factors, as well as genetic predisposition. The microbiome has previously shown to be important for the maintenance of the gut homeostasis. Despite being le

Evaluating structural landscape development in the municipality Upplands-Bro, using landscape metrics indices

The aim of this study was to evaluate and describe the landscape development in an area located in the municipality of Upplands-Bro, Sweden. The main hypothesis was that the landscape patterns in the study area have changed, as I expected to discover that the landscape has undergone structural changes, in form of both changed land use and changed landscape patch composition. The hypothesis was bas

A Qualitative Study on the Interpretation and Application of the Legal Definition of Terrorism in Swedish Courts

When hearing the word ‘terrorism’ something will come to mind, whether it is images from 9/11, 7/7 or any other attack, pictures from terrorist camps in Syria, or something else related to terrorism. But what is terrorism, and can the word be defined sufficiently enough to be used by courts of law? This thesis examines the Swedish courts’ interpretation and application of the legal definition of t

Development of technique for measuring muscle activity and knee motion in children with CP

Cerebral Palsy (CP) has an impact on muscles and movement. This happens due to brain damage before the age of two years. Either sometimes before birth, during childbirth or after birth. According to hjarnfonden.se, 200 children are added annually in Sweden with CP. People living with CP have these weaknesses for the rest of their lives. CP is not progressive disorder, that means brain damage can’

Exploring the Compatibility of E-servicescape Conceptual Model and the Conceptualization of Social Factors in the Context of Taobao and TMall

Prior to the accomplishment of this research, the compatibility of the classic e-servicescape conceptual model in the context Taobao and TMall in China were rarely found among existing e-servicescape literatures due to the standardization taken by both online platforms towards the establishment of individual webshops. Meanwhile, the conceptualization of social factors as social dimension of e-serv

Äldrevänlighet för vem? Representation och inkludering i Uppsala kommun

I denna uppsats analyseras hur en ”äldrevänlig kommun” skapas i en svensk kontext, med Uppsala kommun som exempel. Begreppet äldrevänlighet har vuxit fram genom WHOs arbete och nätverk Age-friendly cities and communities, som syftar till att bemöta en globalt ökande andel befolkning över 60 år. I detta nätverk är idag sex svenska kommuner medlemmar, bland annat Uppsala, och fler än 750 städer delt

A qualitative investigation of consumers’ perception of safety towards high streets in Sweden

The purpose of this study is to explore the way that aspects of the external shopping environment form consumers’ perception of safety, in order to improve our understanding of how consumers experience safety issues in the high streets. Besides, this thesis aims to understand the role of safety in the consumers’ perception towards the shopping environment of high streets and the importance of safe

Investigation of potential sources of crime scene touch DNA

Tack vare dagens extremt känsliga kriminaltekniska DNA-analyser kan det räcka med att en person endast vidrör ett föremål eller en annan person för att göra det möjligt att återfå denna persons DNA från den berörda ytan. DNA från enstaka celler som hittats i ett biologiskt spår på en brottsplats kan räcka för att få fram en DNA-profil som kan användas som mycket stark bevisning och slutligen leda Detectable amounts of DNA may be left behind when an individual touches a surface and research in the forensic science field has shown that some individuals have a higher tendency to transfer their DNA to surfaces than others, a phenomenon known as shedder status. However, there is little evidence to support an unconditional shedder status, and the anatomical origin of deposited DNA and what preci

Comparing single- and multi-echelon methods for inventory control of spare parts at Volvo

Title: Comparing single- and multi-echelon methods for inventory control of spare parts at Volvo Authors: Jakob Bengtsson & Alexander Larsson Supervisors: Johan Marklund, Lund University | Christian Beckers & Johan Lid- vall, Volvo Background: Spare parts logistics is an area particularly concerned with challenges related to inventory control. The parts are vital to secure the functionalit

The Role of Urban Planning in Counteracting Segregation: The Case of Pinelands, South Africa

Segregation är ett vanligt fenomen som uppstår över hela världen. De negativa konsekvenserna av boendesegregation har visat sig vara många för de som bor i mindre välbärgade stadsdelar. Bland konsekvenserna finns bland annat hälsorelaterade motgångar, men även sämre förutsättningar under skolgången och i det framtida arbetslivet har konstaterats. Sydafrika lämpar sig väl för att studera segregatioSegregation is a common phenomenon arising worldwide. Residential segregation has been shown to have several negative consequences for people living in less wealthy neighbourhoods, such as health-related setbacks and being less likely to cope with school. South Africa is an especially well-suited country to study segregation and methods to counteract it to achieve better integration and more harmo

Structure-based design of new antiviral substances against the Venezuelan equine encephalitis virus

The Venezuelan equine encephalitis virus (VEEV) is a highly infectious alphavirus responsible for severe outbreaks and epidemics in the Americas. The nonstructural protein 2 (nsP2) cysteine protease plays a fundamental role in the VEEV replication process, and is therefore, an attractive drug target for structure-based drug design using x-ray crystallography. Generating protein crystals of suffi

Dwarf Galaxies in the Galactic Potential as probes of its internal structure

Mörk materia, som det ofta kallas, utgör den största delen av materian i Universum. Då den inte interagerar med synligt ljus, är det omöjligt att observera dess närvaro direkt. Istället får man tillta indirekta metoder, där man kollar på hur objekt som är synliga påverkas av den mörka materiens närvaro. Ett exempel på en sådan metod är att studera egenskaper hos så kallade stellar streams, eller `Satellite galaxies on bound orbits around the Milky Way (MW) are constantly subject to tidal forces from the MW. If the tidal forces are large enough, they may strip the outermost stars of the satellite, that in turn distribute themselves in long elongated stellar streams. These stellar streams are good probes of the Galactic potential due to the constraints they place on the structure of the pote