The pleckstrin homology (PH) domain is extended in the Btk kinase family by a region designated the TH (Tee homology) domain, which consists of about 80 residues preceding the SH3 domain. The TH domain contains a conserved 27 amino acid stretch designated the Btk motif and a proline-rich region. Sequence similarity was found to a putative Pas GTPase activating protein and a human interferon-gamma

Based on a comparative analysis approach of oasis distributed in arid area of Northwest China, this paper brings up and describes two kinds of oasis distribution pattern: mid-lower reach pattern and middle reach pattern. It is found that the water availability per capita of mid-lower reach pattern is higher than that of middle reach pattern, while the water resources exploitation percentage of mid

Excited states in (196)AU, populated in the Pt-196(p,n) and (d,2n) reactions, were investigated by in-beam gamma -ray and conversion-electron spectroscopy. Two only weakly connected level structures, built on the 2(-) ground state (negative-parity level scheme) and on the 5(+) isomer at 84.7 keV (positive-parity level scheme), are observed. The point of main effort of the present work was the inve

Pancreatitis-associated lung injury is an early-occurring and severe complication, still associated with substantial mortality. A number of inflammatory cells and their products are involved in the initiation and progress of the condition. In the present study, acute pancreatitis (AP) was induced by the intraductal infusion of 5% sodium taurodeoxycholate in the rat. Pulmonary endothelial barrier d

TNP-470 is an acknowledged anti-angiogenic factor, and was studied clinically as an anti-cancer drug. We previously reported on an additional property of this molecule: the intracellular generation of reactive oxygen species in B16F10 melanoma cells. We showed that a massive generation of ROS occurred in the first few hours after treatment with TNP-470 and that this event was critical to subsequen

Popular Abstract in Swedish Vanligt viloelektrokardiogram (EKG) med 12 avledningar är ett av de mest använda redskapen för diagnostik av hjärtsjukdom. Tidigare forskning har visat att detta EKG ej är optimalt, men att nya EKG-metoder kan ge viktig tilläggsinformation. En metod som i flera tidigare studier visat sig innehålla diagnostisk potential är analys av de högfrekventa signalkomponenterna i The standard 12-lead electrocardiogram (ECG) is one of the most commonly used methods for diagnosing heart disease. Standard ECG is not always optimal, however, and new ECG methods can provide additional information. Analysis of high-frequency QRS components (HF-QRS) has been shown to increase the diagnostic performance of the ECG. Since the amplitudes of the HF-QRS are low compared with those vis

A new immunoassay for the detection of hepatitis C core antigen (HCVcoreAg) in peripheral blood during serological window-phase was evaluated among healthy blood donors, commercially available hepatitis C virus (HCV) seroconversion panels and in-house specimens from individuals undergoing seroconversion. Among 1964 low-risk blood donor samples, seven samples were initially reactive but only one wa

Background and Objectives Reagent red blood cells (RBCs) for antibody detection should express certain important antigens as a double dose, that is, the donors must be homozygous for the corresponding alleles. Traditionally, dose is determined by serological typing and known allele frequencies. However, RHD zygosity cannot be predicted serologically owing to the absence of an antithetical antigen,

We discuss LS-forbidden Delta S = 2 transitions of Fe Pi that appear as strong lines in ultraviolet stellar and laboratory spectra. The lines occur because of indirect lever mixing-two close energy levels, w(2)P(3/2) and x(6)P(3/2), are mixed through a third level acting as a catalyst. In transition multiplets, that involve either the w(2)P(3/2) or the x(6)P(3/2) level the normal component is acco

A non-iterative time-domain method for solving the inverse scattering problem for the temporally dispersive, linear, homogeneous, and bi-isotropic slab at normal incidence is presented. The inverse scattering problem is to determine (finite time traces of) the susceptibility kernels of the medium given (finite time traces of) the reflection and transmission kernels, which are obtained by deconvolu

Data avseende bakgrund, sjukdomsbild; både fysisk och psykisk med data hämtades ur ADAD och DOK och genom intervjuer, social- och sjukvårdsjournaler i ett konsekutivt material om 216 klienter som vårdats på Lunden mellan januari 1997 till juni 2000. Totalt 115 flickor/kvinnor (80 LVM- och 52 LVU-flickor) testades med två test BCT och CMPS, psykiska symtom (SCL-90) och personlighetsstörning enligt

The reactions between chalcocite, synthetic copper(I) sulfide, acanthite and synthetic silver(I) sulfide, and aqueous and acetone solutions of potassium ethylxanthate have been studied. Qualitative analysis of the ethylxanthate species present on the surfaces of the sulfide minerals and the synthetic metal sulfides has been made by means of diffuse reflectance infrared Fourier transform (DRIFT) sp