Bone marrow sinusoidal endothelial cells have a specific function as a site of transmigration of hematopoietic stem and progenitor cells and mature blood cells between bone marrow and blood stream. However, the specific characteristics of bone marrow sinusoidal endothelial cells are still largely unclear. We here report that these cells express stabilin-1 and stabilin-2, which in liver sinusoidal

Review of Göran Gruber, "Medeltider. Samtida moblliseringsprocesser kring det förflutnas värden" (Linköping 2010)

The authors describe two dynamic circuit techniques, using only a single-phase clock which is never inverted. This class of circuits has the advantages of simple clock distribution, small area for clock lines reduced clock skew problems, and high speed. Several examples are demonstrated.

Popular Abstract in Swedish Delfiner och andra tandvalar har förmågan att ekolokalisera. Trots att dessa djur länge fascinerat människor genom historien var det först på 1950-talet som man lyckades bevisa att de faktiskt har denna förmåga. Det finns fortfarande många fundamentala frågor angående deras ekolokalisering som ännu inte besvarats, till stor del för att det har krävt alltför avancerad teToothed whales (Odontocetes) use echolocation to navigate and find food in dark or murky waters. A wide range of innovative studies has since the 1960:s been used to characterize their echolocation beam and map out their echolocation skills. In order to render high quality recordings of the sounds emitted by these animals, advanced measurement systems are required. There are still interesting env

Abstract In the field of occupational hygiene much consideration is devoted to the uptake through the human airways, but there are also reports of irritations, complaints and hazards or potential hazards due to particle deposition onto the eyes. There is a need for data regarding the dependence of the deposition rate on particle size and environmental parameters in order to formulate sampling crit

Aims Genetic testing is needed for the formal diagnosis of maturity-onset diabetes of the young (MODY), but this is not widely available. If any MODY biomarkers were known, these could possibly be used as an alternative. Hepatocyte nuclear factor (HNF)-1alpha and HNF-4alpha regulate transcription of genes encoding complement 5 (C5), complement 8 (C8) and transthyretin (TTR), suggesting that these

Enterohemorrhagic Escherichia coli (EHEC) infection leads to marked intestinal injury. Sigmoid colon obtained from two children during EHEC infection exhibited abundant TUNEL-positive cells. To define which bacterial virulence factors contribute to intestinal injury the presence of Shiga toxin-2 (Stx2), intimin and the type III secretion system were correlated with symptoms and intestinal damage.

This paper presents the results of a qualitative study of user behaviour on the World-Wide Web. Eight participants were filmed whilst performing user-defined tasks and then asked to review the video-taped session during prompted recall. This data forms the basis for a series of descriptions of user behaviour and the postulation of a number of underlying cognitive mechanisms. Our results indicate t

Specialutvecklad elektronik för rehabilitering avhjärnskadade är tidsödande och dyrbar att utveckla. Björn Breidegard från Certec, Lunds tekniska högskola, berättar här hur man i stället kan använda enbillig TV-kamera i kombination med dator och programvara. Resultaten är mycket lyckade.

Objective: An association between small for gestational age (SGA) and risk for celiac disease (CD) in childhood has previously been reported. However, this association may reflect residual confounding by genetic or environmental factors. For example, presence of subclinical CD in the mother might be a common cause of both SGA and CD in the offspring. We investigate whether SGA is causally associat

A pronounced membrane selectivity is demonstrated for short, hydrophilic, and highly charged antimicrobial peptides, end-tagged with aromatic amino acid stretches. The mechanisms underlying this were investigated by a method combination of fluorescence and CD spectroscopy, ellipsometry, and Langmuir balance measurements, as well as with functional assays on cell toxicity and antimicrobial effects.

Risk factors for suicidal behaviour include adverse life events as well as biochemical parameters acting, e.g. within the hypothalamic-pituitary-adrenal axis and/or monoaminergic systems. The aim of the present investigation was to study stressful life events and biological stress markers among former psychiatric inpatients, who were followed up 12 years after an index suicide attempt. At the time