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Aims: Animal studies indicate a role for 11 beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) in the development of obesity. The association to glucose homeostasis is less clear. We investigated the relationship between HSD11B1 mRNA levels in adipose tissue and in skeletal muscle and anthropometric and metabolic measurements in humans with and without impaired glucose homeostasis. Methods: Twelve

Waterpipe smoking is becoming increasingly popular worldwide. Research has shown that cigarette smoke, in addition to hundreds of carcinogenic and otherwise toxic compounds, may also contain compounds of microbiological origin. In the present study we analyzed waterpipe smoke for some microbial compounds. Both of the two markers studied, viz 3-hydroxy fatty acids of bacterial lipopolysaccharide (L

The ocean heat transport into the Arctic and the heat budget of the Barents Sea are analyzed in an ensemble of historical and future climate simulations performed with the global coupled climate model EC-Earth. The zonally integrated northward heat flux in the ocean at 70A degrees N is strongly enhanced and compensates for a reduction of its atmospheric counterpart in the twenty first century. Alt

BACKGROUND: Increased levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been shown to reduce the hormones in the HPA axis. In this study we addressed the question whether patients with unmedicated major depressive disorder (MDD) might have altered baseline levels of these natriuretic peptides and an altered response to acute exercise. METHODS: An incremental exerc

BACKGROUND: CYP2J2 is responsible for the production of 5,6 8,9 11,12 and 14,15-epoxyeicosatrienoic acids, vasodilator and anti-inflammatory substances. It is abundantly expressed in human heart and also present in kidney and vasculature. Carriers of a common polymorphism, the CYP2J2-50G>T, rs890293, have reduced expression of CYP2J2 mRNA level in the heart putatively through the interference with

This paper focuses on the use of egress models to assess the optimal strategy in the case of total evacuation in high-rise buildings. The model case study consists of two identical twin towers linked with two sky-bridges at different heights. Each tower is a 50-floor office building. The use of either horizontal or vertical egress components or a combination of them is simulated. The egress compon

Mg-10 mol% LiBH4 composite plus small amounts of FeF3 is investigated in the present work. The presence of LiBH4 during the milling process noticeably modifies the size and morphology of the Mg agglomerates, leading to faster hydrogenation and reaching almost the theoretical hydrogen capacity owing to enhanced hydrogen diffusion mechanism. However, the dehydrogenation of the system at low temperat

Purpose - The employment of continuous ribs in a passage involves a noticeable pressure drop penalty, while other studies have shown that truncated ribs may provide a potential to reduce the pressure drop while keeping a significant heat transfer enhancement. The purpose of this paper is to perform computer-aided simulations of turbulent flow and heat transfer of a rectangular cooling passage with

Understanding past methane dynamics in arctic wetlands and lakes is crucial for estimating future methane release. Methane fluxes from lake ecosystems have increasingly been studied, yet only few reconstructions of past methane emissions from lakes are available. In this study, we develop an approach to assess changes in methane availability in lakes based on delta C-13 of chitinous invertebrate r

Sulfonated fully aromatic polymers with different positions of the acid groups, but with an identical polymer backbone, have been investigated and compared with respect to their properties as proton-exchange membranes. Three different series of sulfonated poly(arylene ether sulfone)s (SPAES) having the same backbone structure were prepared from 4,4’-dichlorodiphenyl sulfone (DCDPS) and 4,4’-dihydr

Background: The Perceived Stress Scale (PSS) measures general stress and the Swedish version, although used in several studies, has not been extensively evaluated for psychometric properties. Aims: This study aimed to investigate psychometric properties and the factor solution of the Swedish 14-item version when used with two samples, namely a mixed Internet sample of women and men (n = 171) and a

We discuss spectral properties of the selfadjoint operator−d 2 dt 2 +t k+1 k+1 − α 2 in L 2 (R ) for odd integers k. We prove that the minimum over α of the ground state energy of this operator is attained at a unique point which tends to zero ask tends to infinity. We also show that the minimum is nondegenerate. These questions arise naturally in the spectral analysis of Schr ̈odinger operators w

We construct a variational formulation for the problem of interpolating seismic data in the case of missing traces. We assume that we have derivative information available at the traces. The variational problem is essentially the minimization of the integral over the smallest eigenvalue of the structure tensor associated with the interpolated data. This has the physical meaning of penalizing the l

This article reports on an investigation of a comprehensive mathematical model for biomass combustion within the one-dimensional model framework. The model takes into account different thermochemical processes, e.g., moisture evaporation, pyrolysis, heterogeneous char reactions, intra-particle heat and mass transfer, and changes in thermo-physical properties. Different approaches to model the vari

The symbiotic fungus Paxillus involutus serves a critical role in maintaining forest ecosystems, which are carbon sinks of global importance. P. involutus produces involutin and other 2,5-diarylcyclopentenone pigments that presumably assist in the oxidative degradation of lignocellulose via Fenton chemistry. Their precise biosynthetic pathways, however, remain obscure. Using a combination of bioch

Abstract Objectives. The Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART) collects data to support the improvement of care for heart disease. Design. SWEDEHEART collects on-line data from consecutive patients treated at any coronary care unit n = (74), followed for secondary prevention, undergoing a

Measurements of the branching ratios of top quark decays into leptons and jets using events with t (t) over bar ( top antitop) pairs are reported. Events were recorded with the ATLAS detector at the LHC in pp collisions at a center-of-mass energy of 7 TeV. The collected data sample corresponds to an integrated luminosity of 4.6 fb(-1). The measured top quark branching ratios agree with the Standar

Recent studies in African contexts have revealed a strong association between spirit possession and severe trauma, with inclusion into a possession cult serving at times a therapeutic function. Research on spirit possession in the Dominican Republic has so far not included quantitative studies of trauma and dissociation. This study evaluated demographic variables, somatoform dissociative symptoms,