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Objectives To examine the under-reporting of pharmaceutical company payments to patient organisations by donors and recipients. Design Comparative descriptive analysis of payments disclosed on drug company and charity regulator websites. Setting UK. Participants 87 donors (drug companies) and 425 recipients (patient organisations) reporting payments in 2012-2016. Main outcome measures. Number and

Background: With the disease burden increasing daily, there is a lack of evidence regarding the impact of COVID-19 in pregnancy. Healthy pregnant women are still not regarded as a susceptible group despite physiological changes that make pregnant women more vulnerable to severe infection. However, high-risk pregnancies may be associated with severe COVID-19 disease with respiratory failure, as out

We conduct a pebble-driven planet population synthesis study to investigate the formation of planets around very low-mass stars and brown dwarfs in the (sub)stellar mass range between 0.01 M- and 0.1 M-. Based on the extrapolation of numerical simulations of planetesimal formation by the streaming instability, we obtain the characteristic mass of the planetesimals and the initial mass of the proto

Context. The HR 1614 is an overdensity in velocity space and has for a long time been known as an old (2 Gyr) and metal-rich ([Fe=H] +0:2) nearby moving group that has a dissolving open cluster origin. The existence of such old and metal-rich groups in the solar vicinity is quite unexpected since the vast majority of nearby moving groups are known to be young. Aims. In the light of new and signifi

Massive multiple-input multiple-out (MIMO) is vital in millimeter-wave (mmWave) bands to obtain large array gains. However, there are practical challenges, such as high hardware cost and power consumption in such systems. A promising solution to these problems is to adopt a hybrid beamforming architecture. This architecture has a much lower number of transceiver (TRx) chains than the total antenna

The orthodox definition of hope suffers from an exclusion problem: it is unable to exclude subjects without hope. In fact, the orthodox definition even allows for despair to be falsely classified as hope. This problem suggests two basic desiderata for a successful analysis of hope; it should solve the exclusion problem, and it should have the resources to explain why, in a given situation, a subje

Nearly axisymmetric gaps and rings are commonly observed in protoplanetary discs. The leading theory regarding the origin of these patterns is that they are due to dust trapping at the edges of gas gaps induced by the gravitational torques from embedded planets. If the concentration of solids at the gap edges becomes high enough, it could potentially result in planetesimal formation by the streami

We present a new analytical equation of state (EOS), which correctly models high pressure theory and fits well to the experimental data of E-Fe, SiO2, Mg2SiO4, and the Earth. The cold part of the EOS is modeled after the Varpoly EOS. The thermal part is based on a new formalism of the Gruneisen parameter, which improves behavior from earlier models and bridges the gap between elasticity and thermo

Sweden has a long tradition of comprehensive upper-secondary education. This began in the early 1970s. It culminated in 1994 with all the programmes having a core curriculum that gave general eligibility to higher education. Conservative and liberal governments have introduced several neoliberal school reforms, which the subsequent social democratic government has done little or nothing to change.

Aim/hypothesis: Human enteroviral infections are suggested to be associated with type 1 diabetes. However, the mechanism by which enteroviruses can trigger disease remains unknown. The present study aims to investigate the impact of enterovirus on autophagy, a cellular process that regulates beta cell homeostasis, using the clonal beta cell line INS(832/13) and human islet cells as in vitro models

Introduction: The aim was to investigate syncytiotrophoblast extracellular vesicle (STBEV) uptake mechanisms by primary endothelial cells, the effects on gene expression, cell activation as well as the effect of aspirin. Methods: The STBEVs were derived using the placental perfusion system, from normal or preeclamptic placentas. Endothelial uptake was analysed with flow cytometry. To elucidate upt

Is complex, ambiguous, and fluctuating social reality measurable? Sometimes yes, perhaps, but often not. At least not in the fairly straightforward way assumed by many researchers. This study is an ethnographic inquiry into data collection during a survey research project. Based on our observations of participants’ spontaneous thoughts and confusions as they filled in questionnaires on “leadership

Introduction: The ideal body position during surfactant nebulization is not known. Objective: The aim of this study was to determine whether body positioning during surfactant nebulization influences surfactant distribution and deposition in the lungs. Methods: Twenty-four 12- to 36-h-old full-termpiglets (1.3-2.2 kg) on nasal continuous positive airway pressure (nCPAP) were randomized into four g

We prove the existence of three-dimensional steady gravity-capillary waves with vorticity on water of finite depth. The waves are periodic with respect to a given two-dimensional lattice and the relative velocity field is a Beltrami field, meaning that the vorticity is collinear to the velocity. The existence theory is based on multi-parameter bifurcation theory.

The structures of the solvated copper(II) ion in water and nine organic oxygen donor solvents with similar electron-pair donor ability, but with different space-demanding properties at coordination, have been studied by EXAFS. N,N′-Dimethylpropyleneurea and N,N,N′,N′-tetramethylurea are sufficiently space demanding at coordination to make the axial positions not accessible, resulting in square-pla

This article addresses the temporality of resistance in the work context. We focus on the challenge of increasingly diminishing professional autonomy in higher education institutions as well as the vulnerability of staff subjected to academic managerialism. A case where a lecturer is exposed to the requirements to revise grading by senior administration is investigated. Power is understood from th

Background: Weighted radiographs are performed to classify acromioclavicular joint dislocations; however, the evidence regarding their usefulness is conflicting. Laboratory studies suggest that internal rotation views can replace weighted radiographs, but this has not been clinically evaluated. Purpose: To evaluate whether weighted or internal rotation radiographs uncovers more high-grade acromioc