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Tamoxifen Represses Breast Cancer Cell Growth by Interacting with SKI-interacting Protein (SKIP)

Tamoxifen is the most common choice of anti-cancer drug for breast cancer in pre-menopausal women. Tamoxifen antagonizes the estrogen proliferative effect by interacting with estrogen receptor. Despite the fact that this treatment has showed a tremendous effect on the survival of patients, resistance to the treatment frequently occurs. Several mechanisms of tamoxifen resistance have been already d

Bridge Museum

I got to know the city of Dujiangyan during my semester in Sustainable Urban Dynamics. I was fascinated by it because it stood out from the image of China I had in my head. Dujiangyan is one of the greenest cities in China, pollution level is much lower than the average, people are living longer and they are known to be laid-back and relaxed. During my site visit I found Dujiangyan to be a city

"There is nothing hidden behind the mask, the mask is all there is": En netnografisk studie om influencers autenticitet och modets kommunikation via kanalen YouTube

This bachelor thesis, “There is nothing hidden behind the mask, the mask is all there is.’ - A netnographic study on influencers’ authenticity and the communication of fashion through YouTube”, aims to understand the conception of authenticity and identity from a fashion perspective through the phenomenon vlogging on YouTube. By applying a netnographic research design, this thesis contains a colle

Exploring Multidimensional Poverty and Microfinance Programmes Impact: Poverty Alleviation In Rural Bangladesh.

This paper examines multidimensional poverty and the effectiveness of microfinance loans in alleviating it using household survey panel data on Bangladesh. Microfinance is an innovative method to financial development of the poor, yet controversial. Several studies investigate this subject matter from a single-dimensional perspective, although, it is generally known that the primary concept of pov

"Jag ska klippa han": Skjutvapenvåldets betydelse och utveckling i Malmö

Violence in general, in Sweden is decreasing, but a specific type of violence, firearm violence among some young men, is increasing. This study is based on acts of violence occurring in the city of Malmö, which has become a symbol of firearm violence in Sweden. By studying social, subcultural and contextual factors, this essay examines the development and the meaning of firearm violence in Malmö.

Drug Discovery and Development: Does the maturity of biotech companies affect their stock return volatility?

Stock return volatility is very high in the biotech industry opposed to other industries and there is limited explanation as to why. Biotech companies invest large amounts of money on research and development to move drugs forward in the clinical trial phases, to get market approval by the regulatory agency FDA. The drug discovery and development process is long and expensive, taking on average 12

In Search of a Stressful Free Life: An Examination of Chinese Lifestyle Migration to Denmark

This thesis explores the Chinese lifestyle migration practice in Jutland of Denmark as a contribution to expanding the categories of Chinese new migrants. The study analyzed ten in-depth interviews on the lifestyle migration practice with Chinese migrants in Denmark. The purpose of this study was to deepen the understanding of the motivations and experiences of Chinese migrants in seek of a better

Exploring Breast Cancer Associated Fibroblast Subpopulations By Using Single-Cell RNA Sequencing

In the tumor microenvironment, Cancer-Associated Fibroblasts (CAFs) are the most represented cell type. Research has shown increasingly the key role of CAFs in cancer growth and evolution, creating the need to identify more clearly and further characterize the CAF population. In this study, looking at single cell RNA sequencing of 768 CAF transcriptomes, we define transcriptionally distinct subpop

Skinn på näsan - En studie i normförskjutning

Status, det socialt konstruerade relativa och relationella värdet på självet, ges och fås i social interaktion. Studiens teoretiska utgångspunkt är att individens sociala interaktioner utgörs av en kontinuerlig kamp för att vinna, eller mot att förlora status och att individer som deltar i mediaintervjuer och berättar om sitt liv gör detta för att upprätthålla eller höja sin sociala status. Det fe

Does size matter?

Since the middle of the nineties, the amount of Regional Trade Agreements has risen sharply. This have created more opportunities for countries to join world trading and be more connected to the rest of the world. However, each trade agreement is unique and it is therefore interesting to evaluate if there are factors that are more important than others. This paper will be looking at combined GDP a

Systemic immune reactions initiated by epileptic seizures and brain inflammation

Epilepsy is a neurological disorder affecting around 1% of the population. It is mainly diagnosed by clinical signs and pathological electrical activity in the brain. Without these parameters, even patients themselves may not always know whether or not they experienced a seizure. Here we investigated the systemic inflammatory response following a prolonged epileptic seizure (status epilepticus; SE

Sustainable fishing - How and why to change the industry

This thesis aims to investigate what kind of policy measure – financial or informative that can be used to push the market towards a more sustainable fishing industry. Consumer reactions and behavior towards these instruments are of great interest in this study. Financial instruments include taxes, subsides, quotas and grants and the informative instruments include the use of information campaigns

The New Keynesian Phillips Curve in a Swedish context

This paper investigates if inflation dynamics in Sweden can be properly modelled by the New Keynesian Phillips Curve (NKPC). Four versions of the NKPC are tested on quarterly data between 1995 and 2016 using Generalized Method of Moments (GMM) as the estimation method. The following versions are empirically tested: the NKPC with output gap, the NKPC with marginal costs, the hybrid NKPC and the sec

Självförverkligande viktigare än karriär - En kvantitativ studie av ungas attityder till arbete

Det finns många olika diskussioner idag kring unga i relation till arbetsliv och arbetsmarknad. Sedan industriella revolutionen har lönearbete blivit en allt viktigare del av våra liv och vårt samhälle. Med anledning av detta vill jag undersöka vilka attityder unga har till arbete i Sverige idag. Ronald Inglehart presenterar en teori om att människors värderingar har förändrats till så kallade pos

Avskrivningar i bostadsrättsföreningar - en fråga i tiden. En studie om bostadsrättsföreningars avskrivningsbeteende i teori och praktik

Syftet med studien är att undersöka om och i så fall hur avskrivningar skiljer sig mellan bostadsrättsföreningar samt undersöka varför en viss avskrivningsmetod och avskrivningstid valts. Studien antar huvudsakligen en kvantitativ forskningsstrategi med deduktiv ansats. Datainsamlingen sker genom att granska årsredovisningar, dess noter och via en strukturerad mailintervju. Den teoretiska referens

Analysis of Inductive Coupling Wireless Power Transfer Systems

Inductive coupling wireless power transfer (WPT) technology is gaining increasing popularity in recent years, especially in the field of wireless charging of portable devices. Although the principles behind WPT systems can be explained using well known results from electromagnetic theory, many questions remain regarding the behavior of such systems. This thesis focuses on identifying and analyzing

Internal Migration and High Skilled Female Labour Supply: A Case Study of Mexico

A recent body of empirical studies has given us a reason to expect that an influx of low-skilled workers can increase high skilled female market labour supply. Most of these studies, however, have focused on developed countries and on investigating the impact as it pertains to immigration. Believing that this same effect might hold in the case of internal migration, in this study, I employ a shift-s

A study on the approach to opportunity recognition by ventures with disruptive characteristics

The aim of the paper was to contribute new insights on how ventures with disruptive characteristics approach opportunity recognition. The construct of disruptive innovation is a relatively new body of theory and there is a lack of clarity on the process of disruption, especially when it comes to making ex ante predictions. It is critical to understand how the process of opportunity recognition inf