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Characterizing bird migration phenology using data from standardized monitoring at bird observatories

Long-term data from standardized monitoring programmes at bird observatories are becoming increasingly available. These data are frequently used for detecting changes in the timing of bird migration that may relate to recent climate change. We present an overview of problematic issues in the analysis of these data, and review approaches to and methods for characterizing bird migration phenology an

Immobilized metal affinity chromatography in open-loop simulated moving bed technology: purification of a heat stable histidine tagged beta-glucosidase.

Open-loop simulated moving bed (SMB) has been used for immobilized metal affinity chromatographic (IMAC) purification of his-tagged beta-glucosidase expressed in E. coli. A simplified approach based on an optimized single column protocol is used to design the open-loop SMB. A set of columns in the SMB represent one step in the chromatographic cycle i.e. there will be one set each of columns for lo

The life and work of Olof Thorin (1912-2004)

This paper reviews Olof Thorin's contributions to mathematical analysis, actuarial mathematics, and probability theory, though in reversed order. In probability theory he is known for his path-breaking work on infinite divisibility. In actuarial mathematics he contributed significantly to the ruin problem. However, his international fame very much relies on his work in mathematical analysis and hi

Early penguin fossils, plus mitochondrial genomes, calibrate avian evolution

Testing models of macroevolution, and especially the sufficiency of microevolutionary processes, requires good collaboration between molecular biologists and paleontologists. We report such a test for events around the Late Cretaceous by describing the earliest penguin fossils, analyzing complete mitochondrial genomes from an albatross, a petrel, and a loon, and describe the gradual decline of pte

Balance between surface complexation and surface phase transformation at the alumina/water interface

This paper synthesizes and expands on the results of a recent series of investigations aimed at characterizing the interactions of orthophosphate, phenylphosphonate, and clodronate ions with hydrous alumina surfaces. The paper shows that gamma-Al2O3 is a thermodynamically unstable substance in water, which undergoes a (surface) phase transformation into bayerite, beta-Al(OH)(3). Furthermore, it al

Combined rCBF and CSF biomarkers predict progression from mild cognitive impairment to Alzheimer's disease.

This study aimed to identify preclinical Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI) using measurements of both regional cerebral blood flow (rCBF) and cerebrospinal fluid (CSF) biomarkers. Baseline rCBF assessments (133Xe method) were performed in 70 patients with MCI who were cognitively stable for 4–6 years, 69 patients with MCI who subsequently developed AD, and 3

A DFT investigation on structural and redox properties of a synthetic Fe6S6 assembly closely related to the [FeFe]-hydrogenases active site

In the present contribution, a density functional theory (DFT) investigation is described regarding a recently synthesized Fe6S6 complex - see C. Tard, X. Liu, S.K. Ibrahim, M. Bruschi, L. De Gioia, S.C. Davies, X. Yang, L.-S. Wang, G. Sawers, C.J. Pickett, Nature 433 (2005) 610 - that is structurally and functionally related to the [FeFe]-hydrogenases active site (the so-called H-cluster, which i

Tolerance Induction Using Lentiviral Gene Delivery Delays Onset and Severity of Collagen II Arthritis

The treatment of rheumatoid arthritis remains suboptimal; thus there is considerable interest in the development of strategies that mediate tolerance to autoantigens. Using lentiviral gene transfer in vivo, we expressed the immunodominant epitope of collagen type II (CII) on major histocompatibility complex class II molecules (MHC II) in a mouse model of destructive arthritis. A sequence correspon

Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes

The aim of this study was to investigate whether polymorphisms in the beta(2)-adrenergic receptor gene (5'LC-Arg19Cys, Arg16Gly, Gln27Glu) are associated with hypertension in patients with or without type 2 diabetes and with the blood pressure levels in normotensive sib pairs. The association study included 291 hypertensive patients without type 2 diabetes, 124 hypertensive patients with type 2 di

Sweden and the dilemmas of neutral intelligence liaison

Throughout the Cold War Sweden pursued a declared policy of nonalignment. Sweden nevertheless established security links with a number of Western powers, first of all Britain and the US. The most extensive links were developed in two areas - military technology and intelligence. Intelligence liaison was of crucial importance for the security of non-aligned Sweden, but also significant for the majo

Texture-modified meat and carrot products for elderly people with dysphagia: preference in relation to health and oral status.

Background : Reduced taste and smell, chewing problems and swallowing dysfunction are common among elderly people and affect perception, food choice and the ability to eat. Objective : To study the preference for texture-modified carrot and meat products in elderly people aiming to meet the needs of people with impaired chewing and/or swallowing. Design : Data were collected using questionnaires

Decolorization of synthetic and real textile wastewater by the use of white-rot fungi

Batch and continuous reactors inoculated with white-rot fungi were operated in order to study decolorization of textile dyes. Synthetic wastewater containing either Reactive Blue 4 (a blue anthraquinone dye) or Reactive Red 2 (a red azo dye) was used during the first part of the study while real wastewater from a textile industry in Tanzania was used in the later part. Trametes versicolor was show

Plasma and dietary carotenoid, retinol and tocopherol levels and the risk of gastric adenocarcinomas in the European prospective investigation into cancer and nutrition

Despite declining incidence rates, gastric cancer (GC) is a major cause of death worldwide. Its aetiology may involve dietary antioxidant micronutrients such as carotenoids and tocopherols. The objective of this study was to determine the association of plasma levels of seven common carotenoids, their total plasma concentration, retinol and alpha- and gamma-tocopherol, with the risk of gastric ade

Ximelagatran Compared with Warfarain for prevention of thromboembolism in patients with nonvalvular atiral fibrillaton: Rationale. Objectives and design of a pair of clinical trials and baseline patient characteristics (SPORTIF III and V).

Background Ximelagatran is a novel, oral direct thrombin inhibitor under investigation as an alternative to warfarin for prevention of thromboembolism in patients with nonvalvular atrial fibrillation (AF). Two long-term studies in patients with AF and at least one additional risk factor for stroke are underway to compare the safety and efficacy of fixed-dose ximelagatran (36 mg bid) without coagu

Cohomology of 3-dimensional color Lie algebras

We develop the cohomology theory of color Lie algebras due to Scheunert-Zhang in a framework of non-homogeneous quadratic Koszul algebras. In this approach, the Chevalley-Eilenberg complex of a color Lie algebra becomes a standard Koszul complex for its universal enveloping algebra, providing a constructive method for computation of cohomology. As an application, we compute cohomologies with trivi

Sticky Landscapes and Smooth Experiences: The Biopwer of Tourism Mobilities in the Öresund Region

As landscapes become ordered according to certain sets of economic, political, ecological or social practices and discourses, other possible orderings become limited in their potential. The article illustrates this with an example taken from the field of tourism and place marketing. The empirical focus is golf experiences in Scania, Sweden, bookable by individual consumers over the Internet. The o

Primary recovery of a genetically engineered Trichoderma reesei endoglucanase I (Cel 7B) fusion protein in cloud point extraction systems.

Here we present data to demonstrate how partitioning of a hydrophilic enzyme can be directed to the hydrophobic detergent-enriched phase of an aqueous two-phase system by addition of short stretches of amino acid residues to the protein molecule. The target enzyme was the industrially important endoglucanase I, EGI (endo-1,4-beta-D-glucan-4-glucanohydrolase, EC 3.2.1.4, Cel7B) of Trichoderma reese

Pre-penetration events in fungal parasitism of nematode eggs

The present investigation deals with the main factors involved in early infection of nematode eggs by fungal parasites. We studied the effect of hydrophobicity on appressorium formation by germlings of Pochonia rubescens (syn. Verticillium suchlasporium), P. chlamydosporia (syn. V. chlamydosporium) and Lecanicillium lecanii (syn. V. lecanii). Appressoria were frequently formed on hydrophobic surfa