Bone substitute as an on-lay graft on rat tibia
Objectives To investigate the capacity of Cerament (R), an injectable bone substitute, to guide bone generation from a cortical surface. Materials and method Cerament (R) was applied to the cortical surface of rat tibiae and investigated histologically after 3, 6 and 12 weeks, using a procedure similar to that performed in sham-operated rats. Results In both groups, the thickness of the bone corte