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När man tog studenten på Kuggis

Historik över den äldre typen av studentexamen (före 1864) som inträdesprov vid Lunds universitet samt något om byggnaden "Kuggis".

Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures

Popular Abstract in Swedish Stroke och hjärtstopp innebär ett minskat eller obefintligt blodflöde (ischemi) till hjärnans celler. Dessa celler är speciellt känliga för ischemi och om blodtflödet är lågt under en längre period leder det till obotliga hjärnskador. Varje år drabbas ungefär 50 000 personer i Sverige av hjärnischemi, vilket gör tillståndet till ett av de vanligaste orsakerna till handiCerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. In order to study particular molecular mechanisms, isolated cellular events and the contribution of individual factors in ischemic d

Equilibrium and Kinetic Studies of the Binding of DNA to Cationic Liposomes

The objective of this work was to study the formation of DNA-cationic vesicle complexes (lipoplexes). These complexes are interesting not only from a fundamental point of view but also as promising candidates for gene therapy. The approach taken was to study first the cationic vesicles by themselves. This will allow us to better understand the "complexation mechanism" upon the addition of DNA. The

Cationic Interactions with Nucleic Acids With Focus on Anticancer Active Platinum(II) Complexes

It is well documented that the antitumour activity of the Pt(II)-complex cisplatin, and similar anticancer active complexes, is a result of metalation of DNA, and thereby inhibition of cell proliferation. Since nucleic acids are polyanions at physiological pH, the rate of adduct formation with positively charged complex, as the hydrolyzed Pt(II) complexes studied in this work, is influenced by the

Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

Popular Abstract in Swedish En ny metod för att syntetisera avancerade kolhydrater har utvecklats. I en utvärdering har två kolhydratstrukturer, viktiga intermediat i ett nytt cancervaccin, syntetiserats.A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).

Perception and judgement of life quality across projected societies

The focus of the presentation is on the individual’s comprehension of “citizenship”. Study and analysis of citizenship concerns a person’s co-operative interaction with various physical and social surroundings as well as the cognitive integration of these surroundings. A person can achieve this integration through development of his abilities of judgement. Thus the aim is to make apparent the kind

Acoustical detection of venous stenosis in Hemodialysis patients using principal component analysis

In this paper, a feature extraction method based on principal component analysis was developed for classification of the vascular access’s condition in hemodialysis patients. The assessment of the method was carried out by discriminating between before and after angioplasty sound recordings as well as before angioplasty and reference recordings. The results showed that when before and after angiop

The Interplay Between Selection And Constraints On Adaptive Divergence And Phenotypic Evolution

Under natural or sexual selection, individuals with advantageous traits or combinations of traits will be more successful than their peers at surviving and/or reproducing. Provided these traits are heritable, meaning that they have a genetic basis, the traits combinations which are selected for, will increase in frequency in the population. When selection is intense and persistent, adaptive traits

Speglingar av Småland

Varför är Småland ett landskap som fascinerar? Kanske för att det är så mångsidigt och omväxlande, likt en brokig mosaik. Dess historia är rik och man har aldrig kunnat tala om ett Småland eller en småländsk identitet. I denna antologi möts tio forskare kring frågan avd som egentligen är småländskt. Läsaren tas med till Astrid Lindgrens Värld och till det småländska Glasriket. De möte tyska och da

Medical Laser-Induced Thermotherapy - Models and Applications

Heat has long been utilised as a therapeutic tool in medicine. Laser-induced thermotherapy aims at achieving the local destruction of lesions, relying on the conversion of the light absorbed by the tissue into heat. In interstitial laser-induced thermotherapy, light is focused into thin optical fibres, which are placed deep into the tumour mass. The objective of this work was to increase the under