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The Efficacy and Safety of Vertebral Augmentation : A Second ASBMR Task Force Report

Vertebral augmentation is among the current standards of care to reduce pain in patients with vertebral fractures (VF), yet a lack of consensus regarding efficacy and safety of percutaneous vertebroplasty and kyphoplasty raises questions on what basis clinicians should choose one therapy over another. Given the lack of consensus in the field, the American Society for Bone and Mineral Research (ASB

Larson's scaling laws, and the gravitational instability of clumpy discs at high redshift

Gravitational instabilities play a primary role in shaping the clumpy structure and powering the star formation activity of gas-rich high-redshift galaxies. Here, we analyse the stability of such systems, focusing on the size and mass ranges of unstable regions in the disc. Our analysis takes into account the mass-size and linewidth-size scaling relations observed in molecular gas, originally disc

Prenatal arsenic exposure is associated with increased plasma IGFBP3 concentrations in 9-year-old children partly via changes in DNA methylation

Exposure to inorganic arsenic (As), a carcinogen and epigenetic toxicant, has been associated with lower circulating levels of insulin-like growth factor 1 (IGF1) and impaired growth in children of pre-school age. The aim of this study was to assess the potential impact of exposure to As on IGF1 and insulin-like growth factor-binding protein 3 (IGFBP3) as well as DNA methylation changes in 9-year-

Combined electric resistivity tomography and seismic refraction tomography in brackish water in saltsjön in Stockholm

Electrical resistivity tomography (ERT) combined with seismic refraction tomography (SRT) were performed in brackish water in Saltsjön in Stockholm. Results from a test survey with measurements along two lines are presented, whereas a larger survey is in progress at the moment of writing. Geological interpretation of the obtained models fits well with the documentation from drilling, and show that

Gaia Data Release 2 : The astrometric solution

Context. Gaia Data Release 2 (Gaia DR2) contains results for 1693 million sources in the magnitude range 3 to 21 based on observations collected by the European Space Agency Gaia satellite during the first 22 months of its operational phase. Aims. We describe the input data, models, and processing used for the astrometric content of Gaia DR2, and the validation of these resultsperformed within the

DNS study of the bending effect due to smoothing mechanism

Propagation of either an infinitely thin interface or a reaction wave of a nonzero thickness in forced, constant-density, statistically stationary, homogeneous, isotropic turbulence is simulated by solving unsteady 3D Navier-Stokes equations and either a level set (G) or a reaction-diffusion equation, respectively, with all other things being equal. In the case of the interface, the fully develop

Precision resonance energy scans with the PANDA experiment at FAIR: Sensitivity study for width and line shape measurements of the X(3872)

This paper summarises a comprehensive Monte Carlo simulation study for precision resonance energy scan measurements. Apart from the proof of principle for natural width and line shape measurements of very narrow resonances with PANDA, the achievable sensitivities are quantified for the concrete example of the charmonium-like X(3872) state discussed to be exotic, and for a larger parameter space of

Modulus Zero-Forcing Detection for MIMO Channels

We propose a modulus based zero-forcing (MZF) detector for multi-input multi-output (MIMO) channels. Traditionally, a ZF detector nulls out interference from other layers when detecting a certain layer. While this is conceptually simple, it can result in considerable noise-enhancement. In many communication systems, finite alphabets such as M quadrature-amplitude-modulation (QAM) are used, which c

Marital status and 5-year mortality : A population-based prospective cohort study

Objectives: The aim was to investigate the association between baseline marital status and mortality using survival (Cox-regression) analysis. Study design: This is a prospective cohort study. Methods: The public health survey by Scania in 2008 was linked to the Swedish cause of death register. This prospective cohort study includes 12,245 men and 14,969 women aged 18–80 years, and 538 men and 362

p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate

The mechanism of how organ shape emerges and specifies cell fate is not understood. Pancreatic duct and endocrine lineages arise in a spatially distinct domain from the acinar lineage. Whether these lineages are pre-determined or settle once these niches have been established remains unknown. Here, we reconcile these two apparently opposing models, demonstrating that pancreatic progenitors re-loca

The trajectory of functional decline over the last 4 months of life in a palliative care population : A prospective, consecutive cohort study

Background: Understanding current patterns of functional decline will inform patient care and has health service and resource implications. Aim: This prospective consecutive cohort study aims to map the shape of functional decline trajectories at the end of life by diagnosis. Design: Changes in functional status were measured using the Australia-modified Karnofsky Performance Status Scale. Segment

Physical-density integral equation methods for scattering from multi-dielectric cylinders

An integral equation-based numerical method for scattering from multi-dielectric cylinders is presented. Electromagnetic fields are represented via layer potentials in terms of surface densities with physical interpretations. The existence of null-field representations then adds superior flexibility to the modeling. Local representations are used for fast field evaluation at points away from their

Passage comprehension performance in children with cochlear implants and/or hearing aids : the effects of voice quality and multi-talker babble noise in relation to executive function

Purpose: Speech signal degradation such as a voice disorder presented in quiet or in combination with multi-talker babble noise could affect listening comprehension in children with hearing impairment. This study aims to investigate the effects of voice quality and multi-talker babble noise on passage comprehension in children with using cochlear implants (CIs) and/or hearing aids (HAs). It also a

Yacon (Smallanthus sonchifolius) Leaf Extract Attenuates Hyperglycemia and Skeletal Muscle Oxidative Stress and Inflammation in Diabetic Rats

The effects of hydroethanolic extract of Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), and hydrophilic antioxidant capacity (HAC) in serum and IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in soleus. The rats

Strategic communication management in the non-profit sector: a simplified model

A model for strategic communication management was developed in South Africa on the basis of the excellence study and relationship management theories. This normative, theoretical model has been applied as part of a project in non-profit organisations (NPOs), government institutions and small-to-medium sized companies. However, the operational reality of organisations’ communication practices has

Familial colorectal cancer risk in half siblings and siblings : Nationwide cohort study

Objective: To explore the risk of colorectal cancer in family members of patients with colorectal cancer, with an emphasis on subtypes of second degree relatives, especially half siblings, which were lacking in the literature. Design: Ambidirectional cohort study. Setting: Nationwide Swedish Family Cancer Data (record linkage). Participants: All people residing in Sweden and born after 1931, with