Popular Abstract in Swedish Neuroblastom är en allvarlig cancerform som nästan enbart drabbar barn. Denna typ av tumörer hittas i vävnader av det sympatiska nervsystemet (vilket är en del av det icke viljestyrda nervsystemet i kroppen). Allra vanligast är det att tumörerna bildas i binjuren, ett organ placerat strax ovanför njuren. Cancer är en komplex sjukdom och varje tumör är speciell på sitt sCells adapt to oxygen shortage, hypoxia, by inducing a transcriptional shift governed mainly by Hypoxia Inducible Factor (HIF)-1 and HIF-2. In various cancer forms, including neuroblastoma, high expression of HIF-2α correlates with disseminated disease and poor outcome. It has become evident that HIF-1 and HIF-2 are differentially regulated over time and by oxygen levels. HIF-2α is expressed in a

Time-resolved terahertz spectroscopy was employed for the investigation of charge-transport dynamics in benzothiadiazolo-dithiophene polyfluorene ([2,7-(9,9-dioctylfluorene)-alt-S,S-(4',7'-di-2-thieny1-2',1',3'-benzothiadiazole)]) (APFO-3) polymers with various chain lengths and in its monomer form, all blended with an electron acceptor ([6,6]-phenyl-C61-butyric acid methyl ester, PCBM). Upon phot

Anmälan av avhandling av THERESE ENARSSON, Brottsoffer i rättskedjan. En rättsvetenskaplig studie av förhållandet mellan brottsoffers rättigheter och rättsväsendets skyldigheter, 258 s.

The disaccharide trehalose stabilizes proteins against unfolding, but the underlying mechanism is not well understood. Because trehalose is preferentially excluded from the protein surface, it is of interest to examine how trehalose modifies the structure and dynamics of the solvent. From the spin relaxation rates of deuterated trehalose and (17)O-enriched water, we obtain the rotational dynamics

I den här kunskapssammanställningen tar vi upp frågor som rör hur ett förändrat klimat kan komma att påverka tillväxt och skörd av olika jordbruksgrödor, samt hur klimatet kan påverka risken för angrepp av nya och redan etablerade skadegörare och växtsjukdomar i Sverige. Ökad temperatur leder till förlängning av växtsäsongen och utrymme för produktionsökning. I takt med att klimatet blir varmare k

We propose a powerful hardware architecture for pixel shading, which enables flexible control of shading rates and automatic shading reuse between triangles in tessellated primitives. The main goal is efficient pixel shading for moderately to finely tessellated geometry, which is not handled well by current GPUs. Our method effectively decouples the cost of pixel shading from the geometric complex

We present an analysis of the colloidal dynamics of particles in a mixture of two solvents subjected to evaporation. For simplicity, only one out of the two solvents is considered to be volatile. The evaporation generates a distribution of the solvent concentration in the system. As the particles selectively interact with the solvents, their migration becomes affected by a "chemotaxis" force, caus

A changing climate is expected to have profound effects on many aspects of ectotherm biology. We report on a decade-long study of free-ranging sand lizards (Lacerta agilis), exposed to an increasing mean mating season temperature and with known operational sex ratios. We assessed year-to-year variation in sexual selection on body size and postcopulatory sperm competition and cryptic female choice.

The coordination polymer [Fe(SCN)(2)(1,2-bis(4-pyridylmethylene)hydrazine)(2)](n) [Fe(phenanthroline)(3)](2n)(ClO4)(2n)center dot n1,2-bis(4-pyridylmethylene)hydrazine center dot 4nH(2)O 1 was crystallised from a MeOH/MeCN solution and the structure consists of layered (4,4) 2D-nets with supramolecular ([Fe(phen)(3)](2)bphz)(4+) units in the pores and disordered water and perchlorate anions. The s

We compute the Hausdorff and Minkowski dimension of subsets of the symbolic space Sigma(m) ={0, ... , m-1}(N) that are invariant under multiplication by integers. The results apply to the sets {x is an element of Sigma(m): for all k, x(k)x(2k) ... x(nk) = 0}, where n >= 3. We prove that for such sets, the Hausdorff and Minkowski dimensions typically differ.

Lund University, Sweden, is the only seat of learning having Sociology of Law (hereafter SoL) at all levels in Europe. SoL was initiated in 1972 as a department at the Social Science Faculty, with professor Per Stjernquist as chair. Later on, for some 10 years, SoL was a division within the department of Sociology but from January 2006, SoL is an autonomous department at the Social Science Faculty

The aim of this study was to investigate associations between time use in daily activities and sociodemographic and clinical factors in order to identify individuals with persistent mental illness at risk of having an imbalance in daily activities, as reflected in their time use and daily rhythm. Participants (n=103) were selected from a psychiatric outpatient unit using a randomized stratified se

Palynological analyses were carried out on 50 samples from the Ovedskloster 1 (O1) and 2 drillcores (O2), southern Sweden. The study revealed well-preserved palynological assemblages including 77 spore species in 28 genera, and some additional forms retained under open nomenclature. The spore assemblages are collectively dominated by trilete spores in terms of abundance and diversity and have been

OBJECTIVE: To estimate the prevalence of spondyloarthritis and its subtypes. METHODS: The Swedish healthcare organisation comprises a system where all inpatient and outpatient care is registered by a personal identifier. For the calendar years 2003-7, all residents aged ≥15 years in the southernmost county of Sweden (1.2 million inhabitants) diagnosed by a physician with spondyloarthritis (ankylo

Background Subclinical cobalamin deficiency is common in the elderly, but the sensitivity and specificity of serum total cobalamin for this diagnosis is poor. Serum holotranscobalamin (holoTC), a measure of biologically available cobalamin, is considered a better marker for early cobalamin depletion than total cobalamin. However, in elderly populations, health-related reference intervals for holoT

With the aim to reconsider lifestyle values in relation to economic rationality in small tourism and hospitality businesses, we focus on the “commercial home” as a site where boundaries between personal and commercial values are constantly performed in practice. Through an interactionist analysis of the narrative of a B&B and gallery owner, we illustrate the emergence of intimacy as a commerci