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BACKGROUND: BRCA1 and BRCA2 are the two major susceptibility genes involved in hereditary breast cancer. This study was undertaken to provide reliable population-based estimates of genetic influence and to characterize the nature and prevalence of BRCA1 and BRCA2 germline mutations in early-onset breast cancer.METHODS: In a series comprising all women diagnosed with breast cancer under the age of

Exposure to organic dust originating from biofuels can cause adverse health effects. In the present study we have assessed the dustiness in terms of microbial components and particles of various biofuels by using a rotating drum as a dust generator. Microbial components from straw, wood chips, wood pellets and wood briquettes were quantified by several methods. Excellent correllations (r greater t

Analys av Edgar G Ulmers filmer med särskilt fokus på hans tidiga jiddisch-språkliga verk.

In apparently monogamous or polygynous birds, sperm from several males may compete to fertilize the eggs laid by one female. In this study we evaluate sperm competition in the European starling (Sturnus vulgaris) by means of a mate-switching experiment. Already-mated males were removed between 1-7 d before their mates started egg-laying, resulting in the female remating with a new male. The origin

BACKGROUND: In the prostate, the importance of sex hormones for its normal development and function is well known. However, it has been proposed that various neuroendocrine (NE) hormones and growth factors may be involved in the pathogenesis of prostatic carcinoma (CaP). Neuroendocrine differentiation appears to be associated with tumour progression and the androgen-independent state, for which th

In this paper, we consider fundamental limitations for DOA estimation with arbitrary lossless antennas or antenna arrays inserted inside a sphere. Spherical vector modes and their associated equivalent circuits and Q factor approximations are employed as a general framework for the analysis. The classical broadband matching theory by Fano is extended to a general multiport S-parameter model of the

Abstract is not available

We study classical and quantum chaos for two interacting particles on the plane. This is the simplest nontrivial case which sheds light on chaos in interacting many-body systems. The system consists of a confining one-body potential, assumed to be a deformed harmonic oscillator, and a two-body interaction of Coulomb type. In general, the dynamics is mixed with regular and chaotic trajectories. The

Discussion about Director/Actor/Film Historian Peter Bogdanovich with regard to his book Who the hell is it? (In Swedish)

Trichoderma cellulases appear in several isoforms which makes their purification and analysis difficult. We used fast protein liquid chromatography (FPLC) to purify three major cellulases and to quantitate these enzymes in reconstituted mixtures during cellulose hydrolysis studies (in lack of specific substrates and because of the synergism between the enzymes such analysis is very difficult, if a

Analysis, assessment, and design of advanced wire-line transmission schemes over multipair copper cables require accurate knowledge of the channel properties. This paper investigates modeling of multiconductor cables based on interpair impedance measurements. A unified approach to the application of the "Cioffi" model is introduced. The direct measurement approach of the underlying interpair imped

We present the resonant inelastic X-ray scattering (RIXS) spectra of BeO at the Be 1s photoabsorption edge. The RIXS spectra excited in the vicinity of the core exciton resonance show two principal features: the scattering on a valence exciton (which at higher excitation energies verges into the characteristic K alpha emission), and a remarkably strong energy loss side-band to the elastic scatteri

The main aim of the study is to explain how pupils´ consciousness of history in comprehensive school is formed and created by teaching. A second aim is to emphasize and to problematise the prerequisites for developing the consciousness of history through teaching. The empirical data consists of three parts: 1. Pupil's associations to the concepts of "time", "past" and "future". 2. Essays (national

Bird migration has been assumed, mostly implicitly, to represent a distinct class of animal behavior, with deep and strong homologies in the various phenotypic expressions of migratory behavior between different taxa. Here the evidence for the existence of what could be called a "migratory syndrome," a tightly integrated, old group of adaptive traits that enables birds to commit themselves to high

Popular Abstract in Swedish Syftet med studien var att utvärdera förändringar avseende psykologiska och sociala variabler före och efter gruppterapi för vuxna kvinnor som utsatts för sexuella övergrepp i barndomen. Ytterligare syften var att beskriva och genom "consumer satisfaction" utvärdera den traumafokuserade gruppterapin, att beskriva kvinnornas hälsa före gruppterapistart och att utvärdera The aim of the study was to evaluate changes in psychological and social variables before and after group therapy for adult women who were sexually abused in childhood. Other aims were to describe and evaluate the traumafocused group therapy by consumer satisfaction, to describe the women's health before group therapy start and to evaluate the impact of single childhood sexual abuse variables on m