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In an environment full of potential pathogens it is of importance for organisms to mount a fast and effective defence. Antimicrobial peptides are ancient and integral effector molecules of the innate immune system. They are found in all kinds of species from bacteria to plants and animals, indicating their importance during evolution. They possess a broad-spectrum antimicrobial activity and some p
Aims. In this paper we demonstrate how Stromgren uvby photometry can be efficiently used to: 1. identify red giant branch stars that are members in a dwarf spheroidal galaxy; 2. derive age-independent metallicities for the same stars and quantify the associated errors. Methods. Stromgren uvby photometry in a 11 x 22 arcmin field centered on the Draco dwarf spheroidal galaxy was obtained using the
A measurement is presented of elastic deeply virtual Compton scattering gamma* p -> gamma p made using e(+) p collision data corresponding to a luminosity of 46.5 pb(-1), taken with the H1 detector at HERA. The cross section is measured as a function of the photon virtuality, Q(2), the invariant mass of the gamma* p system, W, and for the first time, differentially in the squared momentum transfer
This paper examines data from English, Swedish and German in order to find a theoretical distribution that describes the observed relation between word length and frequency. In Swedish and English, most word tokens consist of three letters only, while shorter or longer words occur less frequently. We found that the equation with the general form fexp = a * Lb * cL (a variant of the so-called gamma
Linear enamel hypoplasia (LEH) is transverse lines or bands on the enamel of teeth caused by developmental stress during the formation of the tooth crown. LEH has shown to be useful as a stress marker in studies of health conditions in past populations of pigs. The chronology of LEH and the age at which animals of past populations where afflicted by metabolic stress can be determined based on toot
Hormone-sensitive lipase (HSL) plays a key role in lipid metabolism and overall energy homoeostasis, by controlling the release of fatty acids from stored triglycerides in adipose tissue. Lipases and esterases form a protein superfamily with a common structural fold, called the alpha/beta-hydrolase fold, and a catalytic triad of serine, aspartic or glutamic acid and histidine. Previous alignments
We describe an experimental test of whether particle decay causes wave function collapse. The test uses interference between two well separated, but coherent, sources of vector mesons. The short-lived mesons decay before their wave functions can overlap, so any interference must involve identical final states. Unlike previous tests of non-locality, the interference involves continuous variables, m
The incidence of post-transfusion hepatitis non-A, non-B (PTH-NANB) was prospectively assessed among open-heart surgery patients from the southeast region of Sweden before the introduction of antihepatitis C virus (HCV) blood donor screening. Blood samples for alanine aminotransferase analysis were drawn before and 2, 3, and 4 months after transfusion. Surgery was performed in four centres. Of 190
There is an increasing amount of knowledge on the cytotoxic properties of cyanotoxins, but relatively little is known regarding their fine specificity and mechanisms of action. In this study, we investigated the influence of microcystin-LR and AnTx-a on mouse B- and T-lymphocyte subpopulations in vitro. Cyanotoxins significantly decreased the cell viability after 4 and 24 h, compared to the untrea
Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molekThis thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor
The dependence of effective pair gap on weakly bound neutron orbits is studied in deformed nuclei in comparison with that in spherical nuclei, solving the Hartree-Fock-Bogoliubov equation in a simplified model in coordinate space with the correct asymptotic boundary conditions. In spherical nuclei the effective pair gap of s1/2 neutrons decreases to zero in the limit that the corresponding Hartree
In a regional population of 32,120 liveborn newborn infants 65 (0.2%) had a birthweight less than or equal to 900 g (extremely small low birthweight = ESLBW) with mean gestational age 26.4 (range 22-31) completed weeks of gestation. The total 0-1 year survival rate was 48%. For the 42 infants treated in the Level III regional neonatal intensive care unit (NICU) the 0-1 year survival rate was 55% v
The etiology of ethanol-associated osteopenia is not fully understood. A direct inhibitory effect of ethanol on osteoblast function has been suggested by in vitro and in vivo studies. In this study, we measured biochemical markers for bone formation (osteocalcin, bone specific alkaline phosphatase, procollagen-1-c-terminal peptide) and resorption (c-terminal telopeptide and urine deoxypyridinoline
Numerical simulations using Large Eddy Simulation (LES) are applied to turbulent swirling flow fields. The swirling motion is often introduced into combustors to act as flame holders or enhance the mixing between species. Different turbulence models capture the swirling motion more or less accurately. LES is well suited for understanding details of swirling flows. It resolves all the large scales
