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Weight and height separated provide better understanding than BMI on the risk of revision after total knee arthroplasty : report of 107,228 primary total knee arthroplasties from the Swedish Knee Arthroplasty Register 2009–2017

Background and purpose — Obesity defined as increased BMI is commonly associated with higher revision rates following total knee arthroplasty (TKA). We examined the effect of BMI on the rate of revision after TKA, for both infection and other reasons, and analyzed weight and height separately to provide better understanding of the risk profile. Patients and methods — The Swedish national knee arth

Intact coronary and myocardial functions after 24 hours of non-ischemic heart preservation

Objectives. The aim of this study was to investigate endothelium dependent relaxation (EDR) in coronary artery and the myocardial contractility after 24 h of non-ischemic heart preservation (NIHP). Design. Explanted cardioplegic hearts from six pigs were preserved by NIHP for 24 h. The perfusion medium consisted of an albumin containing hyperoncotic cardioplegic nutrition-hormone solution with ery

Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

Failures in Alzheimer's disease (AD) drug trials highlight the need to further explore disease mechanisms and alterations of biomarkers during the development of AD. Using cross-sectional data from 377 participants in the BioFINDER study, we examined seven cerebrospinal fluid (CSF) and six plasma biomarkers in relation to β-amyloid (Aβ) PET uptake to understand their evolution during AD. In CSF, A

Transoral robotic surgery in the management of head and neck squamous cell cancer with unknown primary

Background: Transoral robotic surgery (TORS) assisted base of the tongue (BOT) resection has been suggested as part of the work-up for head and neck squamous cell cancer with unknown primary (HNSCC-CUP). Success rates vary with regard to identification of primary BOT lesions, and cases with likely such lesions appear to be included in previous reports. Objectives: To analyse the possible benefits

Electrospun fabrication of nanofibers as high-performance cathodes of solid oxide fuel cells

The oxygen reduction reaction (ORR) activity can strongly affect the performance of solid oxide fuel cells (SOFCs). To improve the electron transfer and enhance active sites for reactions in cathode, La0.8Sr0.2MnO3 mixed with Y2O3-stabilized ZrO2 (LSM/YSZ) nanofibers were co-fabricated by the electrospinning method. The fibers were well characterized and the electrochemical properties were evaluat

A Cliometric Model of Unified Growth: Family Organization and Economic Growth in the Long Run of History

This chapter explores the role of gender equality on the long-run economicand demographic development path of industrialized countries. It accounts forchanges in fertility, technology and income per capita in the transition fromstagnation to sustained growth. Our unified cliometric growth model of femaleempowerment suggests that changes in gender relations, triggered byendogenous skill-biased techn

Regional Patterns of Economic Development: A Typology of French Departments during the Industrialization

The purpose of this chapter is to describe and explain regional patterns of economic development as revealed by data on about 70 variables for France in the middle of the 19th century. The development process occurred at different speed across space. The process turned out to be specific and varied across French counties. The characteristics can be classified in a three part taxonomy based on coun

Gender Gap in Numeracy and the Role of Marital Status : Evidence from 19th century France

Evidence of conventional human capital indicators (e.g. literacy, educational attainment, years of schooling) by marital status is rare or inexistent for the period prior to the 20th century. An indicator of human capital frequently used for the pre-1900 period is the age heaping. We employ this method to chart and analyze the heterogeneity and gender-specific differences of cognitive abilities (n

The Structure and Classification of Botulinum Toxins

Botulinum neurotoxins (BoNTs) are a family of bacterial protein toxins produced by various Clostridium species. They are traditionally classified into seven major serotypes (BoNT/A-G). Recent progress in sequencing microbial genomes has led to an ever-growing number of subtypes, chimeric toxins, BoNT-like toxins, and remotely related BoNT homologs, constituting an expanding BoNT superfamily. Recen

Predicted basal metabolic rate and cancer risk in the European Prospective Investigation into Cancer and Nutrition

Emerging evidence suggests that a metabolic profile associated with obesity may be a more relevant risk factor for some cancers than adiposity per se. Basal metabolic rate (BMR) is an indicator of overall body metabolism and may be a proxy for the impact of a specific metabolic profile on cancer risk. Therefore, we investigated the association of predicted BMR with incidence of 13 obesity-related