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Extreme solar particle events (ESPEs) are infrequent yet highly potent manifestations of solar activity. These events result in the production of significant amounts of cosmogenic isotopes (CIs): 10Be, 36Cl, and 14C, which are subsequently deposited in natural stratified archives. Analyzing CI measurements from these archives allows us to assess the particle fluxes during ESPEs. In this study, we
Pulmonary veno-occlusive disease (PVOD) is a lethal variant of pulmonary hypertension. The degree of pulmonary arterial involvement varies. Here, we compare two PVOD patients who were transplanted at 8 years of age, whereof one is a homozygous EIF2AK4 mutation carrier. Tissue was imaged with synchrotron-based micro-CT and the results were compared with clinical data and sectioned tissue was analyz
The extent to which bullying victimization is associated with an increased risk of obsessive-compulsive disorder (OCD) has received little empirical attention. This longitudinal, population-based, genetically informative study examined whether self-reported bullying victimization at age 15 was associated with a clinical diagnosis of OCD in the Swedish National Patient Register and with self-report
Transverse momentum pT spectra and anisotropic flow distributions are studied for charmonia and charmed hadrons produced in Pb-Pb collisions and measured with the ALICE detector at the CERN Large Hadron Collider (LHC). The investigations are performed within the framework of the Statistical Hadronization Model with the transverse dynamics evaluated using predictions from relativistic viscous hydro
In this master's thesis a fully automated method is presented for seg-menting bones and cartilage in magnetic resonance imaging (MRI) of theknee. The knee joint is the most complex joint in the human body andsupports the weight of the whole body. This complexity and acute task ofthe knee joint leads to a disabling disease called Osteoarthritis among theadult population. The disease leads to loss o
The problems of de-blurring, de-noising, compression and segmentation are fundamental problems in image processing. Each of these problems can be formulated as a problem to find some approximation of an initial image. To find this approximation one needs to specify the approximation space and in what space the error between the image and its approximation should be calculated.Using the space of Bo
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Accumulating evidence indicates a potential role for bacterial lipopolysaccharide (LPS) in the overactivation of the immune response during SARS-CoV-2 infection. LPS is recognized by Toll-like receptor 4, mediating proinflammatory effects. We previously reported that LPS directly interacts with SARS-CoV-2 spike (S) protein and enhances proinflammatory activities. Using native gel electrophoresis a
We conducted a multiancestry genome-wide association study of prostate-specific antigen (PSA) levels in 296,754 men (211,342 European ancestry, 58,236 African ancestry, 23,546 Hispanic/Latino and 3,630 Asian ancestry; 96.5% of participants were from the Million Veteran Program). We identified 318 independent genome-wide significant (P ≤ 5 × 10 -8) variants, 184 of which were novel. Most demonstrat
Self-efficacy is tightly intertwined with person-centered care and correlates with engaging in self-care behaviors, an important part of hypertension treatment. Evidence indicates that e-Health-based self-management interventions could increase self-efficacy. The objectives of this study were to investigate whether an intervention with a person-centered approach supported by e-Health technology ca
Background: In addition to peripheral neuropathy of various kinds, diabetes can also cause central neuropathy, which among other things can manifest itself as premature cognitive dysfunction, often linked to vascular dysfunction. Although the link between diabetes and cognitive dysfunction was discovered more than 100 years ago and has important clinical implications, this diabetes complication re
This paper revisits the doll Estrid, a reconstruction of a Viking Age woman that was excavated by archaeologists in the mid-1990s in Täby, Vallentuna parish, Sweden. The woman was shortly after the excavation attributed to be Estrid, a woman’s name mentioned on rune stones in proximity of the excavated burial. After this ‘identification’, the Estrid phenomenon has taken different shapes and paths,
With a critical focus on the interpretative work of the Committee on Economic, Social and Cultural Rights, this article sets out the parameters of applying non-discrimination under article 2(2) of the International Covenant on Economic, Social and Cultural Rights in conjunction with article 11(1) on the right to adequate housing to discrimination suffered by migrants and refugees in access to exis
BACKGROUND: Treatment for breast cancer poses major challenges and leads to a variety of side-effects and problems that affect life for a long time. Experiences and symptoms vary, and research indicates a lack of structures for ensuring individualized rehabilitation. This qualitative focus group study aims to explore the experience of women with BC after participating in a complex randomized contr
Pollinators have been negatively impacted by agricultural intensification, loss of natural habitats and habitat fragmentation. This has raised concern about the persistence of plant species dependent on insect pollination in semi-natural grasslands where these are remnants of larger grazed areas, now surrounded by intensive agriculture and forests. To better understand landscape composition effect
In the present study, three-dimensional direct numerical simulations (DNS) of experimental ammonia/air premixed jet flames with different turbulent intensities were performed. The DNS results were first compared to the measurements with good agreements. Based on the DNS data, the turbulent flame structure, stabilization mechanism and NO emission characteristics of the flames were investigated. It
BackgroundThis systematic literature review evaluates the effectiveness of Quality Management Tools (QMTs) in reducing Hospital-Associated Infections (HAIs) among adult inpatients in hospital settings.MethodsThe systematic literature review, following the PRISMA guideline, systematically analyzed relevant studies from 2013 to 2023 across three electronic databases: PubMed, CINAHL, and EMBASE, usin
