Monocytes, macrophages and dendritic cells (DCs) are developmentally related regulators of the immune system that share the monocyte-macrophage DC progenitor (MDP) as a common precursor. Unlike differentiation into DCs, the distal pathways for differentiation into monocytes and monocyte-derived macrophages are not fully elucidated. We have now demonstrated the existence of a clonogenic, monocyte-

Purpose: Cis-acting regulatory SNPs resulting in differential allelic expression (DAE) may, in part, explain the underlying phenotypic variation associated with many complex diseases. To investigate whether common variants associated with DAE were involved in breast cancer susceptibility among BRCA1 and BRCA2 mutation carriers, a list of 175 genes was developed based of their involvement in cancer

BACKGROUND: People with intellectual disabilities (ID) are known to have more diseases and are believed to start aging earlier than the general population. The population of older people with ID is growing, but knowledge about their use of healthcare is limited. This study aimed to explore somatic healthcare utilisation patterns among people with ID living in Sweden, in comparison with the general

This paper argues that innovation diffusion is not a rational implementation process, but more accurately portrayed as a highly social process, involving sets of intermediate organizations that contribute to a product’s reputation. Empirically it builds on two case studies, one cultural and one science-based, to demonstrate there are industry differences in where innovations get validated: validat

Technological advancements in combination with significant reductions in price have made it practically feasible to run experiments with multiple eye trackers. This enables new types of experiments with simultaneous recordings of eye movement data from several participants, which is of interest for researchers in, e.g., social and educational psychology. The Lund University Humanities Laboratory r

The Swedish school system comprises three school types: preschool, compulsory school (9 years) and secondary school (3 years). The latest curriculum reform was completed in 2011, updating policy documents and restructuring syllabuses, clarifying subject specific abilities and knowledge requirements. In 2012, national tests in geography were instituted for years 6 and 9, yielding support for equal

We use rich longitudinal survey and register data on Swedish individuals to examine the relationship between financial strain and mental health. Specifically, we consider the longitudinal relationships between payment difficulties and subjective (self-reported anxiety) as well as objective (psychiatric drug use) measures of mental ill-health. Among previously healthy individuals, payment difficult

A recurrent problem in ecology and conservation biology is to estimate the risk of population extinctions. Extinction probabilities are not only imperative for conservation and management, but may also elucidate basic mechanisms of the regulation of natural populations. The usual way of modelling stochastic influence on population dynamics has been to assume that the external noise is uncorrelated

Research indicates that hybrid ventures face more complexchallenges than other ventures, due to multiple institutional logics. Institutionallogics theory suggests that this is due to different institutional backgrounds thatinfluence actor perspectives and expectations on decision making authority andventure identity, which in turn result in tensions and possible conflicts,especially over time. The