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T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis

The immunodominant T-cell epitope that is involved in collagen-induced arthritis (CIA) is the glycosylated type II collagen (CII) peptide 256-270. In CII transgenic mice, which express the immunodominant CII 256-270 epitope in cartilage, the CII-specific T cells are characterized by a partially tolerant state with low proliferative activity in vitro, but with maintained effector functions, such as

Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: Six-month study

Several studies have shown that alpha-ketoglutaric acid (AKG) increases serum levels of proline and has beneficial effects on skeletal development. We studied the effect of alpha-ketoglutaric (AKG) acid calcium salt (6 g AKG and 1,68 Ca/day) or calcium alone (1.68 Ca/day) on serum C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin (OC), as well as lumbar spine bone minera

Ambiguous configurations for the 1D structure and motion problem

In this paper we investigate, determine and classify the critical configurations for solving structure and motion problems for 1D retina vision. We give a complete categorization of all ambiguous configurations for a 1D (calibrated or uncalibrated) perspective camera irrespective of the number of points and views. It is well-known that the calibrated and uncalibrated case are linked through the ci

Ab initio MP2 and DFT study of the thermal Syn elimination reaction in ethyl formate

The thermal elimination reaction that appears in some polycarbonates has been studied by density functional theory (DFT) and ab initio methods of different levels. This work has been focused in the elimination process of ethyl formate, as a good model of this kind of reaction. Different minima and the transition state have been found to characterize the thermal elimination reaction, and the activa

Det förgångna är framtiden : Ursprungsfolk och självbestämmande i Hawai´i

Popular Abstract in Swedish Det förgångna är framtiden är en socialantropologisk studie av ett politiskt skeende som pågått under de senaste 20 åren och som handlar om hur ursprungsfolket kanaka maoli i Hawai´i fått rätt till självbestämmande och andra särskilda rättigheter. Kanaka maoli har använt en diskursiv strategi som handlat om att de en gång i tiden varit ursprungligt suveräna och att dennThe sovereignty- and self-determination movements of indigenous peoples are a salient factor on the political agenda in many western world countries. Indigenous peoples in Hawai´i and elsewhere have become increasingly politicised in hope of changing their relationship with the states within which they are located. The discourse of indigenous peoples turn around the concept ”First Nations” whose c

Land och fæ : strukturellt-rättsfilologiska studier i fornnordiskt lagspråk över beteckningar för egendom i allmänhet med underkategorier

Popular Abstract in Swedish Denna undersökning inventerar beståndet av beteckningar för EGENDOM I ALLMÄNHET och för MOBIL och IMMOBIL EGENDOM i de regionala medeltida nordiska lagarna (dvs. de danska och svenska landskapslagarna, de norska lagtingslagarna samt den isländska Grágás). Materialet analyseras språkgeografiskt med avsikten att skapa en relativ termkronologi. En grovanalys visar attféThis study investigates the stock of words for PROPERTY IN GENERAL with the subcategories MOVABLE and IMMOVABLE PROPERTY in the regional medieval Scandinavian laws and makes a linguistic-geographical analysis of these words with the aim of establishing a relative term chronology. A crude analysis shows that fé/fæ for PROPERTY IN GENERAL and land for IMMOVABLE PROPERTY were the oldest

Frequency-Domain Analysis of Linear Time-Periodic Systems

In this paper we study how a system with a time-periodic impulse response may be expanded into a sum of modulated time-invariant systems. This allows us to define a linear frequency-response operator for periodic systems, called the harmonic transfer function (HTF). Similar frequency-response operators have been derived before for sampled-data systems and periodic finite-dimensional state-space sy

Phenotype prediction by DNA-based typing of clinically significant blood group systems in Jordanian blood donors.

BACKGROUND AND OBJECTIVES: During the past 10 years several DNA-typing methods have been developed to complement routine serological typing for determination of polymorphisms in the ABO, RH, KEL, JK and FY blood group genes. However, the molecular basis of blood groups can differ widely between ethnic groups. The purpose of this study was to evaluate selected DNA-based methods for phenotype predic

Pre-operative evaluation with MR in tetralogy of fallot and pulmonary atresia with ventricular septal defect

PURPOSE: To assess whether MR imaging could replace angiography in preoperative evaluation of patients with tetralogy of Fallot and pulmonary atresia with ventricular septal defect (VSD), especially since the surgical correction was done earlier than was previously the rule. MATERIAL AND METHODS: Fourteen patients with tetralogy of Fallot (n = 10) or pulmonary atresia with VSD (n = 4), mean age 7.

Effect of resonant impurity scattering on the carrier dynamics in Si/SiGe quantum wells

We have performed Monte Carlo simulations of the electron drift velocity in a delta-doped Si/SiGe quantum well, for high and low temperatures as well as strong and weak electric field. All scattering matrix elements of intervalley phonons, acoustic phonons, interface roughness, and impurity ions are calculated from the electron wave functions. Special attention was paid to the resonant state scatt

Rapid refocusing system for the Euro50 telescope aimed at removing the perspective elongation of laser beacons

To obtain full sky coverage, astronomical adaptive optics systemsrequire Na Sodium Beacons (SBs) (also referred to as Laser Guide Starsor LGSs) located at heights extending from 85 to 100 km. When viewed atthe edge of large telescopes these SBs appear elongated. For the Euro5050 meter aperture telescopes this elongation amounts to 6 to 9arcseconds when the laser is launched from a point on the tel

Basic instrumentation for Hall A at Jefferson Lab

The instrumentation in Hall A at the Thomas Jefferson National Accelerator Facility was designed to study electro-and photo-induced reactions at very high luminosity and good momentum and angular resolution for at least one of the reaction products. The central components of Hall A are two identical high resolution spectrometers, which allow the vertical drift chambers in the focal plane to provid

Effects of polyamines on intracellular calcium and mechanical activity in smooth muscle of guinea-pig taenia coli

The effects of the polyamines putrescine, spermidine and spermine on the mechanical activity in smooth muscle from guinea-pig taenia coli were investigated. Tissue concentrations of spermidine and spermine were about 240 and 160 nmol g-1, respectively, while the putrescine concentration was much lower (4 nmol g-1). Intracellular [Ca2+] was determined using the Fura-2 method and the effects of extr

Fruit and vegetable consumption in relation to risk factors for cancer: a report from the Malmo Diet and Cancer Study

OBJECTIVE: To examine the associations between the consumption of fruit and vegetables and other markers of cancer risk. DESIGN: A cross-sectional survey within the population-based prospective Malmo Diet and Cancer (MDC) Study. Information on food habits was collected through the modified diet history method designed and validated for the MDC Study. Data on smoking and alcohol habits, leisure tim

Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens

Developing a reliable and quantitative assessment of the potential virulence of a malignancy has been a long-standing goal in clinical cytometry. DNA histogram analysis provides valuable information on the cycling activity of a tumor population through S-phase estimates; it also identifies nondiploid populations, a possible indicator of genetic instability and subsequent predisposition to metastas