In this work, a real-time sampling/analytical method for on-line measurements of two newly discovered cyclomaltodextrinases (CDases) has been developed and evaluated. This novel methodology not only allows the final products to be investigated, but it also reveals enzyme-specific differences in the degradation pathways during the hydrolysis of different substrates, which is a great advantage in th

The aim of this study was to describe the clinical characteristics in relation to final amputation level in diabetic patients with foot ulcers. In a prospective series, 187 consecutively presenting patients were investigated. From admission until final outcome, the patients were treated by a multidisciplinary team both as in- and out-patients. All the patients had one or more signs of neuropathy a

We measured bacterial growth on phototransformed dissolved organic matter (DOM) leached from eight different primary producers. Leachates (10 mg C liter(-1)) were exposed to artificial UVA + UVB radiation, or kept in darkness, for 20 h. DOM solutions were subsequently inoculated with lake water bacteria. Photoproduction of dissolved inorganic carbon (DIC), ranging from 3 to 16 mug C liter(-1) h(-1

Research on event-related potential (ERP) correlates of auditory deviance-detection in newborns provided inconsistent results; temporal and topographic ERP characteristics differed widely across studies and individual infants. Robust and reliable ERP responses were, however, obtained to sounds (termed 'novel' sounds), which cover a wide range of frequencies and widely differ from the context provi

Popular Abstract in Swedish I den första avhandlingen på svenska om den finlandssvenske estetikern, filosofen och författaren Hans Ruin (1891–1980) förenas ett intresse för det litterära uttrycket med ett intresse för människan bakom orden. Litteraturen som mänskligt dokument, som spåret efter en människa, och dess funktion som överbringare av erfarenheter och insikter står i centrum för framställThe first dissertation in Swedish of the Finno-Swedish aesthetician, philosopher and writer Hans Ruin (1891–1980) combines an interest in the literary expression with an interest in the man behind the words. Literature as a human document, as the footprint of a human being, and its function as a bearer of experiences and insights is at the heart of the characterisation. The title of this dissertat

Thin films of CeO2 with and without a thin layer of copper oxide were prepared by rf magnetron sputtering on surfaces of alpha-Al2O3 (sapphire) substrates. Careful characterisation of the surfaces was performed down to the atomic level using high-resolution electron-microscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. Surprisingly, the as-deposited, corrugated ceria surfaces,

A numerical and analytical investigation is performed on a dissolved air flotation (DAF) pilot tank by using the residence time distribution (RTD) of the conservative dye rhodamine measured with a fluorometer. The experiments are numerically analyzed with regard to the total volume of the DAF tank separation zone in order to detect differences between observed separation zone flow structures in pr

We have developed force-field parameters for the hydrogen-abstraction transition state of aliphatic hydroxylation by cytochrome P450 using the Q2MM approach. The parametrization is based on quantum chemical (B3LYP) transition-state structures and Hessian matrices for 24 diverse substrate models (14 in the training set and 10 in the test set). The force field is intended to be applicable to any dru

I antologin får du ta del av sju olika analyser av det utmanande arbetet med att åstadkomma inriktning och samordning av samhällets resurser i samband med skogsbranden. Publikationen är ett utvecklingsbidrag och är tänkt att ge vägledning till förbättrad förmåga att hantera framtidens samhällsstörningar. Bakom texterna står sju olika författare som utgått från ambitionen att publicera ett transp

Simultaneous two-species imaging using single-shot planar laser-induced fluorescence have been performed to record high quality image pairs of CH/OH, CH/CH2O and OH/CH2O to visualize the flame front structures in swirl-stabilized lean premixed methane/air flames. The results show that the investigated flames exhibit various flame front structures distinctly in space, which covers: (1) the corrugat

Background - This interim 12-month analysis is a part of an open-label, observational, prospective study on health outcomes and cost impact of levodopa/carbidopa intestinal gel (LCIG, Duodopa) in Parkinson disease (PD). The specific aim was to investigate clinical and health-related quality of life (HRQoL) effects in routine care. Methods - Unified PD rating scale (UPDRS) was the primary efficacy

Background: Esophagus cancer (EC) is among the five most common cancers in both sexes in Iran, with an incidence rate well above world average. Social rank (SR) of individuals and regions are well-known independent predictors of EC incidence. The aim of current study was to assess gender and social disparities in EC incidence across Iran's provinces through 2003-2009. Materials and Methods: Data o

A complete reliability study of the DC and RF characteristics for InGaAs nMOSFETs with aluminium oxide/ hafnium oxide dielectric is presented. The main stress variation at high frequencies is related to a threshold voltage shift, whereas no decrease is found in the maximum of the cut-off frequency and RF-transconductance. Constant gate stress leads to a charge build up causing a threshold voltage

Much of global passenger transport is linked to tourism. The sector is therefore of interest in studying global mobility trends and transport-related emissions. In 2005, tourism was responsible for around 5% of all CO(2) emissions, of which 75% were caused by passenger transport. Given the rapid growth in tourism, with 1.6 billion international tourist arrivals predicted by 2020 (up from 903 milli

Recent studies have identified mutations in the complement regulatory gene factor I (CFI) that predispose to atypical hemolytic uremic syndrome (aHUS). CFI is a two-chain serine protease in which the light chain carries the catalytic domain while the heavy chain's function is unclear. It downregulates the alternative and classical complement pathways by cleaving the alpha' chains of C3b and C4b in

We show that coherent anti-Stokes Raman lineshapes do not follow known spectral profiles if the time asymmetry of realistic laser pulses is taken into account. Examples are given for nanosecond and picosecond laser pulses commonly employed in frequency-resolved coherent anti-Stokes Raman scattering. More remarkably, the analysis suggests an effect of line narrowing in comparison to the customary a