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Coronary artery calcification and aortic valve calcification in patients with kidney failure : a sex-disaggregated study

Background: Chronic kidney disease (CKD) is linked to an increased cardiovascular disease (CVD) burden. Albeit underappreciated, sex differences are evident in CKD with females being more prone to CKD development, but males progressing more rapidly to kidney failure (KF). Cardiovascular remodelling is a hallmark of CKD with increased arterial and valvular calcification contributing to CKD. However

Avtalsslutande vid internationella köp av varor

I FN-konventionen om internationella köp - CISG - ges bestämmelser om ingående av avtal om internationella köp av varor, köparens och säljarens respektive skyldigheter, påföljder vid kontraktsbrott och andra aspekter rörande sådana köp. I samband med sitt tillträde till konventionen förklarade Danmark, Finland, Norge och Sverige i enlighet med artikel 92(1) bl.a. att de inte skulle vara bundna av

Challenges and opportunities for reuse of products and materials with fire safety requirements – A Swedish perspective

The construction sector is of great importance to the Swedish economy, but its impact on the climate is significant and the sector accounts for about 40% of Sweden's total energy consumption. The sector also generates a significant share of the total material flows and waste quantities in the society. Thus, due to the large impact of the construction sector, there are great opportunities to contri

HPV self-sampling versus healthcare provider collection on the effect of cervical cancer screening uptake and costs in LMIC : a systematic review and meta-analysis

Background: Cervical cancer is a major global health issue, with 89% of cases occurring in low- and middle-income countries (LMICs). Human papillomavirus (HPV) self-sampling tests have been suggested as an innovative way to improve cervical cancer screening uptake and reduce the burden of disease. The objective of this review was to examine the effect of HPV self-sampling on screening uptake compa

Influence of the interannual variability of meteorological drought on the cross-interactions of ecological and hydrological drought in the central Spanish Pyrenees

This paper analyzes the influence of the interannual variability of climatic drought on ecological and hydrological droughts for a basin in the central Spanish Pyrenees using variables derived from observations and hydro-ecological simulation in order to determine the possible connection between meteorological, ecological and hydrological drought considering a cascading approach and encompassing d

Higher vegetation sensitivity to meteorological drought in autumn than spring across European biomes

Europe has experienced severe drought events in recent decades, posing challenges to understand vegetation responses due to diverse vegetation distribution, varying growth stages, different drought characteristics, and concurrent hydroclimatic factors. To analyze vegetation response to meteorological drought, we employed multiple vegetation indicators across European biomes. Our findings reveal th

Elucidation of the low-expressing erythroid CR1 phenotype by bioinformatic mining of the GATA1-driven blood-group regulome

Genetic determinants underlying most human blood groups are now clarified but variation in expression levels remains largely unexplored. By developing a bioinformatics pipeline analyzing GATA1/Chromatin immunoprecipitation followed by sequencing (ChIP-seq) datasets, we identify 193 potential regulatory sites in 33 blood-group genes. As proof-of-concept, we aimed to delineate the low-expressing com