Aims: Exaggerated hepatic glucose production is one of the hallmarks of type 2 diabetes. Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound. However, the effects of SFN in hepatocytes are yet unclear. Accumulating evidence points to the close structural contacts between the ER and mitochondria, known as mitochondria-associated ER membranes (MAMs), as important hubs for

Introduction: The primary aim of this study was to compare the objective and subjective outcomes and short-term complication rates of an adjustable single-incision mini-sling (SIMS) vs. standard mid-urethral slings (SMUS). The secondary aim was to report pain perception and complications at the one-year follow up. Material and methods: The study was designed as a multicenter prospective randomized

Background: Given that metformin is the most common pharmacological therapy for type 2 diabetes, understanding the function of this drug is of great importance. Hepatic metformin transporters are responsible for the pharmacologic action of metformin. However, epigenetics in genes encoding metformin transporters has not been fully elucidated. We examined the DNA methylation of these genes in the li

Kangaroo Mother Care (KMC) supports parents' role at the neonatal intensive care unit (NICU). To enhance parents' provision of KMC, it is essential to obtain knowledge of what parents perceive as supportive factors and barriers regarding their opportunities to perform KMC. Aim: To identify factors that parents of preterm infants perceived as supportive factors or barriers for their performance of

Objectives: Among patients who underwent primary surgery for non-small cell lung cancer (NSCLC), recurrent disease is frequent and cannot be accurately predicted solely from TNM stage and histopathological features. The aim of this study was to examine the association of tumor markers in pre-operative serum with recurrent disease. Material and methods: Blood samples were collected prior to lung ca

Objective: Vaspin (visceral adipose tissue derived serine protease inhibitor, SERPINA12) is associated with obesity-related metabolic traits, but its causative role is still elusive. The role of genetics in serum vaspin variability to establish its causal relationship with metabolically relevant traits was investigated. Methods: A meta-analysis of genome-wide association studies for serum vaspin f

The current live attenuated vaccine against tuberculosis, BCG, poses a risk of disseminated infections in immunocompromised subjects. Therefore, in this study we compared the protective effect of a heat-killed bacille Calmette-Guerin (H-kBCG) vaccine given in a new adjuvant (Eurocine L3) with the protection provided by the conventional live attenuated BCG vaccine in mice (C57BL/6 and BALB/c) chall

The present dissertation concerns typologically unusual ways of encoding manner information, namely verbal affixes (manner affixes), incorporated constituents (incorporated manner modifiers) and auxiliary verbs (manner adverbial verbs). A key proposal is that all three are overt realizations of syntactic heads merged in the clausal spine, thereby presenting novel data that can be used to probe int

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/descriptions/xp5226.pdf - 2025-04-11

Köpcentra är ofta städade och snygga vilket gör att man som besökare inte tänker på allt avfall som kan uppstå. Men hur hanterar köpcentra, mer specifikt NOVA Lund, allt avfall som uppstår? Denna studie går till botten med vad som är rätt åtgärd att ta för NOVA för att kunna växa, men ändå klara av det ökade trycket av avfall. Detta genomfördes eftersom NOVA Lund vill uppgradera sitt nuvarande avfIn this study an evaluation of the ways in which the shopping mall NOVA Lund can improve its current waste management practices was conducted. This was done because NOVA plans to upgrade their waste management system. A survey was conducted where the staff of the 68 stores and 7 restaurants were inquired on the current system. The stores were asked to rank what kind of waste they encounter the mos

Vid fel i köpt egendom har köparen möjlighet att rikta skadeståndsanspråk mot säljaren. Beroende på om den köpta egendomen är fast eller lös egendom skiljer sig skadeståndsgrunderna åt. En gemensam skadeståndsgrund är säljarens ansvar för utfästelser, som fastställer att säljaren blir skadeståndsskyldig om egendomen avviker från vad säljaren har utfäst. Vid fel i fast egendom har HD har genom NJA In case of defects in purchased property, the buyer has the possibility to claim damages for the loss. Depending on whether the purchased property is real or personal property, the grounds for damages differ. A common ground for damages is the seller’s liability for representations, which establishes that the seller is liable for damages if the property differs from what the seller has represented

Barnadråpsbestämmelsen medför en privilegiering för det fall en kvinna uppsåtligen dödar sitt nyfödda barn. Straffet för brottet är fängelse i högst sex år. Trots att dagens reglering sällan tillämpas i praxis, har dess föregångare –barnamordsbestämmelsen– en mörk och omfattande historia, som under 1700-talet utgjorde det dominerande straffrättsliga och kriminalpolitiska problemet i samhället. SamThe infanticide provision entails a privileging of the case when a woman intentionally kills her newborn child. The range of punishment for the crime is imprisonment for a maximum of six years. Despite its rare application today, the provision has a dark and extensive history and constituted a significant challenge for criminal law and criminal policy during the 18th century. The societal view of

Denna uppsats ämnar till att kartlägga företags rättsliga ansvar enligt Art 7.2.b, 7.4 och 22.2 i Corporate Sustainability Due Diligence Direktive (CSDDD). Det understryks hur ineffetkivt contractual cascading kan vara för att förebygga brott mot mänskliga rättigheter i ett företags värdekedja. Genom att tillämpa en rättsdogmatisk metod har slutsatsen dragits att det finns tillräckliga skäl enligThe thesis aims to map out the corporate legal responsibility of companies according to Article 7.2.b, 7.4, and 22.2 of the Corporate Sustainability Due Diligence Directive (CSDDD). It emphasizes how ineffective contractual cascading have been in preventing human rights violations in a company's value chain. One conclusion drawn from the application a legal dogmatic method is that there are su

Vilka utvecklingsmöjligheter har Region Kalmar läns arbete med substitution? Att ta bort eller byta ut farliga kemikalier mot något annat alternativ som är mindre skadligt för miljön och hälsa brukar benämnas som substitution. Människor kommer idag i kontakt med farliga kemikalier på flera olika sätt, till exempel genom vissa plaster och elektronik eller på arbetsplatser där farliga kemikalier hanChemicals are becoming more and more important and almost essential for human life. Therefore, the human exposure of hazardous chemicals has increased substantially. Alternative assessment (AA) is a method used for substitution of hazardous chemicals and requirements for substitution are included in European health and safety legislation. As part of Region Kalmar läns environmental and sustainabil

Idag återfinns sexistiska kommentarer på sociala medieplattform, trots att företagen bakom har regler för vad som får publiceras. Sexism är ett strukturellt problem som kan påverka kvinnor negativt, både fysiskt och psykiskt och kan leda till självcensur. Ge- nom en kvalitativ textanalys syftar denna uppsats att testa om tre principer kan användas för att analysera om sexistiska kommentarer från FToday, sexist comments can be found on social media platforms, despite social media companies having rules on what is allowed to be published. Sexism is a structural prob- lem which can negatively affect women, both physically and mentally, and could lead to self-censorship. Through a qualitative text analysis, this essay aims to investigate whether sexist comments from Facebook and Instagram are

Kejsarsnitt, utebliven amning och antibiotika ökar risken för sjukdomar Hur många av dina vänner har någon form utav allergi? Pollen, nötter? Trots att vår sjukvård är bättre än någonsin har vi en stor ökning av sjukdomar i samhället, bland annat allergier. Varför är det så? Kliande ögon, snuva, nästäppa… Låter det bekant? Var tredje svensk har någon form utav allergi, vilka kan vara allt från lBackground and Aim The aim was to investigate the effects of four early life factors – delivery mode, feeding method, probiotics, and antibiotics – on disease development in childhood. This was done by conducting a structured literature review. Methods A literature search was performed in PubMed, Google Scholar and ReadCube Papers for studies published between January 2000 and October 2022. For e