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Cost-effectiveness of internet-based cognitive-behavioural therapy and physical exercise for depression
Children’s use of gesture and action with static and dynamic verbs
Transportation and regional inequality: the impact of railways in the Nordic countries, 1860–1960
Explaining gender-typed educational choice in adolescence : The role of social identity, self-concept, goals, grades, and interests
Comparison between DC ERT and moving multi-depth electrostatic arrays in an urban context
Familial risks of cancer as a guide to gene identification and mode of inheritance
Living with dementia with Lewy bodies: an interpretative phenomenological analysis
Objective: To explore the subjective experience of living with dementia with Lewy bodies (DLB). Design A qualitative study of in-depth interviews using interpretative phenomenological analysis. Setting: A memory clinic in Malmö, southern Sweden. Participants: A purposive sample of five male participants with DLB between the ages of 78 and 88 years and disease duration of 1.5-7 years. Results: Thre
Elevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol
Elevated basal insulin secretion under fasting conditions together with insufficient stimulated insulin release is an important hallmark of type 2 diabetes, but the mechanisms controlling basal insulin secretion remain unclear. Membrane rafts exist in pancreatic islet cells and spatially organize membrane ion channels and proteins controlling exocytosis, which may contribute to the regulation of i
A Method for Assessing Margin and Sensitivity of Electricity Networks With Respect to Repair System Resources
Modern society is becoming increasingly dependent on a continuous supply of electricity. In order to maintain the safety and security of society and its citizens, it is therefore necessary that electricity networks are resilient toward disruptions whether caused by natural disasters, sinister attacks, or other. Margin and sensitivity are two crucial aspects of the resilience concept which have so
Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes
Impaired beta-cell function is key to the development of type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART) is an islet peptide with insulinotropic and glucagonostatic properties. Here we studied the role of endogenous CART in beta-cell function. CART silencing in INS-1 (832/13) beta-cells reduced insulin secretion and production, ATP levels and beta-cell exocytosis. This was su
Equipped for resistance : an agonistic conceptualisation of the public library as a verb
Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome
Here we hypothesized that exercise in dihydrotestosterone (DHT) or letrozole (LET)-induced polycystic ovary syndrome mouse models improves impaired insulin and glucose metabolism, adipose tissue morphology, and expression of genes related to adipogenesis, lipid metabolism, Notch pathway and browning in inguinal and mesenteric fat. DHT-exposed mice had increased body weight, increased number of lar
FinEstBeaMS – A wide-range Finnish-Estonian Beamline for Materials Science at the 1.5 GeV storage ring at the MAX IV Laboratory
MNE microfoundations and routines for building a legitimate and sustainable position in emerging markets
A number of studies have analysed how multinational enterprises (MNEs) develop appropriate strategies for managing the institutionally different contexts of various markets. However, we still know rather little about how MNEs manage different institutional pressures when they operate in emerging markets. These markets have a higher level of uncertainty as their values and structures undergo change