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Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. For instance, notochord, endothelial cells, and pancreatic mesenchyme are essential for the development of the pancreas. N-cadherin deficient-embryos suffer fro
Diabetes - the imbalance in glucose homeostasis is partially caused by loss or dysfunction of pancreatic insulin producing β cells or development of insulin resistance. In Type 1 diabetes β cells are destroyed in the process of an autoimmune attack, whereas in Type 2 diabetes, islets produce insufficient amounts of insulin or the insulin cannot be used adequately. So far, the most promising therap
This thesis aims to propose, evaluate and apply test procedures for rationality, weak separability and efficiency. In particular, it focuses on nonparametric revealed preference procedures. This approach has the advantage of not having to stipulate any functional form for the utility function, unlike the parametric approach which relies on finding a suitable functional form for the utility functio
In most sociological paradigms the importance of human interaction for the understanding of societies, is a well established fact. In this study, the focus is the interaction between human beings and material things as it is occurring in practice. Such an approach with its important consequences for understanding both social life and self, is often overlooked in studies within the field of sociolo
This thesis is divided into two distinct parts. The first part contains three chapters, co-authored with Joakim Westerlund, that deal with the analysis of unit root testing, and the second part consists of two chapters on slope homogeneity testing. Chapter 2 continues and extends the analysis in Westerlund (Empirical Economics 37:517–531, 2009), who demonstrates that the performance of the popula
Wind erosion is a serious threat to soil resources as it causes depletion of the fine fractions that may result in a less fertile soil. Wind erosion encompasses several processes of which many are related to climate variables. To date, there is little work performed on how wind erosion relates to climate and climate change. In this thesis, atmospheric circulation and wind erosion were analysed to
This project focuses on how to determine the chloride content in concrete structures exposed to marine environment in an accurate way. When analyzing dust from dry drilling in concrete, it is very often a fact that the chloride profiles show extensive variations even if the sampling has been performed within a very concentrated area with the sampling points close to each other. Several authors hav
Socioeconomic Inequalities in the KidneyTransplantation Process: A Registry-BasedStudy in SwedenYe Zhang, MSc,1Ulf-G. Gerdtham, PhD,1,2,3Helena Rydell, MD,4,5,6and Johan Jarl, PhD1Background.Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and educaBackground. Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and education, and access to (i) the kidney waitlist (first listing), and (ii) kidney transplantation conditional on waitlist placement. Adjustment will be made for a number of medical and
‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining
Background: Relenza represents the first neuraminidase inhibitor (NI), a class of drugs that also includes the drug Tamiflu. Although heralded as breakthrough treatments in influenza, NI efficacy has remained highly controversial. A key unsettled question is why the US Food and Drug Administration (FDA) has approved more cautious efficacy statements in labelling than European regulators for both dBackgroundRelenza represents the first neuraminidase inhibitor (NI), a class of drugs that also includes the drug Tamiflu. Although heralded as breakthrough treatments in influenza, NI efficacy has remained highly controversial. A key unsettled question is why the United States Food and Drug Administration (FDA) has approved more cautious efficacy statements in labelling than European regulators f
Western European states are faced by societies with increasing ethnic, cultural and religious diversity as a result of migration flows. Advocates of multiculturalism have tried to address these potential challenges by advocating the accommodation of minorities within the recipient society. This study argues that the normative and practical measures suggested by multiculturalists tend to be de-cont
Stefan Larsson’s Conceptions in the Code makes a significant contribution to sociolegal analysis and also represents a valuable contribution to conceptual metaphor theory. By utilising the case of copyright in a digital context it explains the role that metaphor plays when the law is dealing with technological change, displaying both conceptual path-dependence as well as what is called non-legislaStefan Larsson's Conceptions in the Code contributes invaluably to socio-legal analysis and conceptual metaphor theory. By examining cases of digital copyright, Larsson elucidates the role that metaphor plays when law is accommodating technological change, displaying both conceptual path-dependence as well as non-legislative developments in law. Analyses draw from conceptual studies of property sp
Sverige är ett utpräglat småföretagarland och mätt i antal bedrivs en klart övervägande del av företagen som enskild näringsverksamhet. Till skillnad från aktiebolag och andra juridiska personer, som hänför alla inkomster till inkomstslaget näringsverksamhet, ska inkomster eller utgifter för fysiska personer hänföras till endera av inkomstslagen näringsverksamhet, tjänst eller kapital. Avhandlinge
The logistical activity of transport is one of the largest contributors to several environmental problems. One efficient and effective way to decrease the environmental impact from transports is to implement changes in the logistically related strategies and activities applied, such as the selection of transport suppliers. Consideration of the environmental aspect when purchasing transport servic
This thesis deals with various aspects of coordinated voltage control in electric power systems. It consists of an introduction and six papers. The introduction contains a summary of the thesis and tutorials on voltage control and the search methods that have been applied. The first part deals with the coordination of cascaded tap changers in radial distribution feeders. A tuning rule for the con
When attention is drawn to the recovery of resources within waste, the amount and types of waste disposed of at landfills change. A waste management system based on separate kerbside collection, sorting, recycling, and pretreatment with material and/or energy recovery produces new residues, which finally end up at landfills. This is the case in, for example, the US and the EU. As a possible result
In northern Scandinavia and other cold regions, urban drainage systems are often unable to cope with the high volumes of melt water which can be sustained for several weeks. High waste water treatment plant inflows, combined system overflows and low water quality are a few problems associated with snowmelt. However, reports detailing urban snowmelt processes are lacking in the hydrological literat
