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The neutrophil store its effector proteins in several distinct types of cytoplasmic granules, developed sequentially during cell maturation. The different subtypes of granules have unique protein content and functional characteristics. The formation of each granule subtype coincides with the biosynthesis of its content. Granule proteins synthesised during the formation of a granule subtype are thu
Falls and fractures in older people are a common and increasing health problem which causes physical, social and psychological problems for the individual and is costly to society. The aims of this thesis were to investigate accidental falls of patients aged 65 - 74 who attended an orthopedic emergency ward, to investigate reliability of the modified figure of eight (MFE) and compare it with other
The topic of this dissertation is the work of the poet Bruno K. Öijer (b. 1951). My thesis is, that a recognition of how he has assumed the outsider position is vital for an understanding of his work, and that it also may contribute to an explanation of his particular importance in the cultural arena of the early 70s. The thesis is structured in four parts. Part one deals with the concept “outside
Two polymers, alginate and Eudragit S-100 were used as reversibly soluble-insoluble ligand carriers for the selective isolation of enzymes and lectins respectively. These two polymers have the inherent property of being precipitated under well defined conditions. Alginate was made insoluble by the addition of Ca2+ ions, and Eudragit S-100 by a pH shift. The polymers were modified with affinity lig
Infectious pancreatic necrosis virus (IPNV) is a Birnavirus that infects salmonid fish. The infection is usually mortal for fish under six months of age, while older fish become carriers, usually without any signs of infection, and will spread the virus to other susceptible fish and to their offspring. IPNV is an icosahedral, naked virion and the genome consists of two segments of double-stranded
Organizational creativity and psychological well-being. Present day organizations in a globalized society are experiencing external challenges and changes more than ever before and in order to adapt and react to these changes creativity and innovation are seen as some of the most important means. The standpoint in this thesis is that all employees have creative potential, and how the creative pote
Interactions of proteins with other proteins, with polymers and with surfaces are of great practical importance within for instance protein purification, drug delivery, and food technology. The aim of this work is to increase the understanding of protein-protein, protein-polyelectrolyte, and protein-surface interactions, particularly concerning the role of electrostatic interactions in these syste
This thesis in industrial design concerns the challenges and possibilities in meeting demographic shifts and the presumed expectations of today’s and tomorrow’s older generations. The background is the lack of furniture that responds to the demands of older consumers and the lack of knowledge about relationships between people and furniture in their home environments and in various forms of elderl
Helicobacter pylori is a gastric pathogen colonising the gastric mucus layer and epithelium of gastric tissue and is associated with chronic type B gastritis and peptic ulcer disease. The attachment of H. pylori to gastric epithelial cells involves several structures recognised by specific bacterial surface proteins. Since colonisation is an initial and critical step in the development of a chroni
Thermal endometrial destruction by means of a silicone balloon catheter is a new form of treatment for menorrhagia aimed at reducing menstrual blood loss. The purpose of the present work was to study, experimentally, the thermal effects on and the thermal conductivity of uterine tissue, to obtain a basis for the estimation of optimal treatment conditions by means of numerical analyses using a comp
All viruses that infect bacteria, plant, or animal cells involve a genome (RNA or DNA) that is encapsidated by a rigid protein shell. After delivery of the viral genome into the host cell, new capsid proteins, which are encoded by viral DNA or RNA, are expressed and self-assembled into new viral capsids. The main objective of my research was to study the key physical factors of genome ejection tha
Hematopoietic stem cells (HSC) are sufficient and required for life long production of all blood cell lineages. Steady state HSCs are largely quiescent and we demonstrate that the kinetics of HSC cell cycling are slower compared to more committed progenitor cells also during expansion and self-renewal ex vivo and in physiological conditions. Such slow kinetics during cell division might reflect a
The aim of the research presented in this thesis was to provide extended background knowledge concerning several biochemical markers, used for the medical evaluation of pregnant women with suspected or confirmed preeclampsia, in order to improve the reliability of monitoring. Plasma levels of beta-2 microglobulin, cystatin C and beta trace protein are known to reflect renal filtration in non-pregn
This thesis is about aesthetic observance. By these terms I intend to give an account of a social phenomenon considered an angle of approach on the understanding of norms. I narrow down the problems with the perspective from social psychology. The central claim by George Herbert Mead was that mind arises from human interaction. The individual subject by this means appears as an effect. I whish to
The aim was to study digital radiography and to evaluate the influence of image processing on digital dental radiographs for the assessment of periapical lesions. In four studies, artificial bone lesions were made periapically and interradicularly in the mandibular premolar and molar regions. In a clinical study, direct digital radiographic images depicting the periapical bone tissue of different
The work presented in this thesis deals with measuring in-cylinder combustion species and events using different laser-based diagnostic methods. A variety of engine operating modes, like HCCI and partially premixed diesel combustion, have been investigated. In the very first measurements, in-cylinder flow-fields were compared to CFD and steady-state blow rig results. After that, the ignition and
Dementia is a state of permanent loss of cognitive function, most commonly affecting the elderly. With a rapidly growing aged population, the spectrum of disorders that lead to dementia is exerting an ever-increasing toll on patients, families and society alike. The most common dementing disorders are Alzheimer's disease and vascular dementia. Although Alzheimer's disease is very common and was de
This thesis deals with the conceptualisation of da‘wa, ‘the call to Islam’, of the British organisation the Islamic Foundation, and focuses its 25 years of publication of Islamic-English children’s literature. In order to analyse the implications of the new modalities of da‘wa in the late modern Muslim minority context, the present study applies a genealogical perspective. The study explores the
This dissertation examines the interaction between municipal home-helpers and care re-cipients from a social psychological perspective. One of the starting points is a critique of some classical works in the caring science inspired by women’s studies for not taking into consideration that care-giving work constitutes social interaction. The aim is to analyse how elderly people and the home-helpers
Although the civil aviation industry has gone through great technological and commercial change in the last decades, basic civil aviation training has not kept pace accordingly. The changes in civil aviation have rarely resulted in research programs in the field of basic training, which has long received minimal attention from the industry. In the research presented in this thesis, methods for und
