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Objectives: Clinical trials have demonstrated the efficacy of vedolizumab in inflammatory bowel disease (IBD). However, these findings may not reflect the clinical practice. Therefore, we aimed to describe a vedolizumab-treated patient population and assess long-term effectiveness. Materials and methods: Patients initiating vedolizumab between 1 June 2014 and 30 May 2015 were identified through th

Aims To describe weight-change pathways in patients with type 2 diabetes (T2D) and associated healthcare costs using repeated BMI measurements and healthcare utilization data. Methods Patients with newly-diagnosed T2D with body mass index (BMI, kg/m2) at diagnosis and subsequent measures at year 1–3 were identified. Based on three-year BMI change, patients were assigned to one of 27 BMI change pat

Introduction The impact of the increased anticoagulants uptake on incidence rate of ischemic stroke is largely unknown. We assessed time trends in rates of ischemic stroke in patients with incident atrial fibrillation (AF) diagnosed between 2011 and 2013. Materials and methods Population-based retrospective registry study of all 11,500 adults diagnosed with incident non-valvular atrial fibrillatio

The speed and progress of transitions towards renewable energy systems varies greatly between European member states. Among others, these differences have been attributed to the emergence of grassroots initiatives (GIs) that develop radical ideas and sustainable practices. The goal of this paper is to understand the differences in the emergence of GIs for renewable energy in relation to the instit

Low energy buildings have well insulated building enclosures and efficient ventilation heat recovery systems which lead to small transmission and ventilation heat losses. During a large part of the year internal heat gains from people, household electricity and solar heat gains balance the heat losses with zero heating need as a result. All energy uses in a building are part of the buildings energ

Interest in human heredity has a long history in Sweden. In the 1920s the Parliament decided on a State institute for race biology and in the 1930s a sterilization legislation that put eugenics into practice was enacted. During the postwar decades both research and the political-medical practices were successively transformed: medical genetics became established and proclaimed as a new research fi

The idea of Circular Economy is gaining a momentum among companies, households and policy makers. In order to support a smooth transition to this idea, new ways of producing and using products and services are needed, which in turn require innovative business models. Such business models may help companies capitalise on closed resource loops and maintain or improve their competitive position in th

Objective: The objective of this study was to evaluate attachment and its association to obstetric and demographic factors as well as emotional well-being using a standard measure of prenatal attachment during pregnancy. Background: The strength of the mothers’ relationship with her baby has important implications in the postnatal period, influencing the relationship she develops with her child, a

Purpose: This paper has two main aims: to explore fathers' postnatal care experiences with a specific focus on deficiencies and to investigate which service deficiencies remained important for fathers one year after childbirth. Design/methodology/approach: This is a prospective longitudinal study. Two months and one year after birth, the overall satisfaction with care were sought. A care quality i

Aplastic anemia is a rare life-threatening disease. However, since the introduction of immunosuppressive therapy and allogeneic stem cell transplantation, the outcome has improved considerably, and the 5-year survival is reported to be 70–80% in selected patient cohorts. Yet, contemporary population-based data on incidence and survival are lacking. We performed a national retrospective study to de

Aim: To study (a) the covariation between patient reported experience measures (PREMs) and registered process measures of access and continuity when ranking providers in a primary care setting, and (b) whether registered process measures or PREMs provided more or less information about potential linkages between levels of access and continuity and explaining variables. Background: Access and conti