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Reduced inequality in access to stroke unit care over time : A 15-year follow-up of socioeconomic disparities in Sweden

Background: Despite the compelling scientific evidence on the superiority of stroke unit care, far from all acute stroke patients have access to stroke unit care. In congruence with what has been observed when other new methods are introduced in health care, we hypothesized that there has been an inequality in the buildup phase of stroke units but that the gradients between patient groups have dec

Malignancies in Swedish persons with haemophilia : a longitudinal registry study

The aim of the study was to investigate, over time, the incidence of and mortality due to malignant diseases among persons with haemophilia, compared to matched controls. Persons with haemophilia A or B were enrolled via registries at each haemophilia centre, as well as from the National Patient Registry, and were compared to five sex and age-matched controls per patient. Data from the national Ca

Fighting infectious disease: Evidence from Sweden 1870-1940

Even more than in developing countries today, public health strategies to fight infectious disease in the past focused on the prevention of new infections by stopping their spread. These strategies were motivated by new insights into the causes of disease and the modes of transmission in the mid-nineteenth century. By combining longitudinal individual-level data on 17,000 children in a rural/semi-

Sustained Remission Improves Physical Function in Patients with Established Rheumatoid Arthritis, and Should Be a Treatment Goal : A Prospective Observational Cohort Study from Southern Sweden

OBJECTIVE: It has been proposed that remission should be maintained throughout the course of rheumatoid arthritis (RA); however, the evidence supporting this is limited. Physical function measured by the Health Assessment Questionnaire (HAQ) is a major outcome in RA, and HAQ is shown to be one of the strongest predictors of longterm outcomes. The purpose of this study was to investigate the physic

Prognostic instrument for survival outcome in melanoma patients : based on data from the population-based Swedish Melanoma Register

BACKGROUND: Several major analyses have identified a consistent set of independent risk factors for cutaneous malignant melanoma (CMM). A few prognostic models have been presented but some are based on a limited number of patients and others are based on selected groups of patients referred to major institutions. No nationwide population-based prognostic instrument for survival of CMM has been pre

In defence of the fundamental values of society: an analysis of blasphemy trials and debates in Sweden around 1900

Critique of religion and its consequences is a topical theme. The attack on the satirical magazine Charlie Hebdo in Paris in January 2015 made the Western media establishment to rally in defence of freedom of expression, but it also raised the question of the limits of this freedom. There are always defined limits to freedom of expression, which change over time and are adapted to the political sy

Epidemiology of osteoarthritis in Sweden. Register and cohort studies on prevalence and mortality.

Osteoarthritis (OA) is the most common form of arthritis and often causes pain and functional impairment. Despite its high burden on society, knowledge about the occurrence of OA and its associated mortality is sparse. The epidemiology of OA is difficult to determine due to the patients’ fluctuating symptoms and challenges in detecting and defining the radiographic disease. The specific aims of th

Text-to-intonation in spontaneous Swedish

This paper deals with a number of aspects of intonation in spontaneous dialogues in a language technology perspective. The key topics to be addressed are: I) the analysis of global intonation and its interaction with textual structure, II) the implementation of global and textual aspects of discourse intonation in an analysis-by-synthesis environment. We present models for the analyses of intonati

Observed Cognitive Performance and Deviation From Familial Cognitive Aptitude at Age 16 Years and Ages 18 to 20 Years and Risk for Schizophrenia and Bipolar Illness in a Swedish National Sample

Importance: Proposal of an innovative approach to clarify the mechanism through which poor cognitive performance in adolescence impacts risk for schizophrenia (SZ).Objective: To determine whether the developmental processes that predispose to SZ are better reflected by the observed cognitive performance in adolescence or the deviation of that performance from the individual's familial cognitive ap

What PASSes for good? : Experience-based Swedish and hypothetical British EuroQol 5-Dimensions preference sets yield markedly different point estimates and patient acceptable symptom state cut-off values in chronic arthritis patients on TNF blockade

OBJECTIVES: Health utilities derived from answers to generic health-related quality of life (HRQoL) questionnaires such as the EuroQol 5-Dimensions (EQ-5D) are often used in cost-utility analyses (CUAs) of new and expensive treatments. Different preference sets (tariffs) used in the computation of utility values and quality-adjusted life-years (QALYs) from questionnaire responses (health states) y

Internal labour dynamics of a downsizing firm: The Swedish Tobacco Monopoly in the 1920s

Labour management in the past has been the studied by researchers from various disciplines and perspectives. Among labour economists and economic historians, there is an emerging current that aims to test hypotheses derived from theories about internal labour markets. So far, most studies have focused on companies whose workforces have been stable or expanding over time. This paper analyzes the in