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Din sökning på "julie" gav 4765 sökträffar

Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma

The activated B cell (ABC-like) subtype of diffuse large B cell lymphoma (DLBCL) is characterized by chronic activation of signaling initiated by immunoglobulin m (IgM). By analyzing the DNA copy number profiles of 1000 DLBCL tumors, we identified gains of 18q21.2 as the most frequent genetic alteration in ABC-like DLBCL. Using integrative analysis of matched gene expression profiling data, we fou

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Hypoglycaemia (low plasma glucose) is a serious and potentially fatal complication of insulin-treated diabetes. In healthy individuals, hypoglycaemia triggers glucagon secretion, which restores normal plasma glucose levels by stimulation of hepatic glucose production. This counterregulatory mechanism is impaired in diabetes. Here we show in mice that therapeutic concentrations of insulin inhibit g

Ferritin heavy chain in triple negative breast cancer : a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response

Ferritin heavy chain (FTH1) is a 21-kDa subunit of the ferritin complex, known for its role in iron metabolism, and which has recently been identified as a favorable prognostic protein for triple negative breast cancer (TNBC) patients. Currently, it is not well understood how FTH1 contributes to an anti-tumor response. Here, we explored whether expression and cellular compartmentalization of FTH1

Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks

Recent studies have uncovered thousands of long non-coding RNAs (lncRNAs) in human pancreatic β cells. β cell lncRNAs are often cell type specific and exhibit dynamic regulation during differentiation or upon changing glucose concentrations. Although these features hint at a role of lncRNAs in β cell gene regulation and diabetes, the function of β cell lncRNAs remains largely unknown. In this stud

The SAM-Krom biomonitoring study shows occupational exposure to hexavalent chromium and increased genotoxicity in Denmark

Background Hexavalent chromium (Cr(VI)) is a carcinogen. Exposure to Cr(VI) may occur in different industrial processes such as chrome plating and stainless steel welding. The aim of this study was to assess occupational exposure to Cr(VI) in Denmark. Methods This cross-sectional study included 28 workers and 8 apprentices with potential Cr(VI) exposure and 24 within company controls, all recruite

A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX.

Trabecular bone score (TBS) is a grey-level textural index of bone microarchitecture derived from lumbar spine dual-energy X-ray absorptiometry (DXA) images. TBS is a BMD-independent predictor of fracture risk. The objective of this meta-analysis was to determine whether TBS predicted fracture risk independently of FRAX probability and to examine their combined performance by adjusting the FRAX pr

Incidence and outcomes of kidney replacement therapy for end-stage kidney disease due to primary glomerular disease in Europe : findings from the ERA Registry

Background. Primary glomerular disease (PGD) is a major cause of end-stage kidney disease (ESKD) leading to kidney replacement therapy (KRT). We aimed to describe incidence (trends) in individuals starting KRT for ESKD due to PGD and to examine their survival and causes of death. Methods. We used data from the European Renal Association (ERA) Registry on 69 854 patients who started KRT for ESKD du

2009 teddy arsrapport

Rapport till UMAS ledning tisdag 14/11 2006 kl 13 TEDDY årsrapport 1 2010-04-23 TEDDY-studien (The Environmental Determinants of Diabetes in the Young) Årsrapport 2009 TEDDY årsrapport 2 2010-04-23 Bakgrund Vi kan inte leva utan insulin. Ett barn som har fått typ 1 diabetes saknar insulin och tvingas således ta dagliga insulininjektioner och göra ständiga blodsockerkontroller under resten av livet

https://www.teddy.lu.se/sites/teddy.lu.se/files/2009_teddy_arsrapport.pdf - 2025-07-08

Nicklas Guldåker

Universitetslektor Kontaktinformation E-post: nicklas [dot] guldaker [at] keg [dot] lu [dot] se Telefon: +462223279 Mobil: +46 72 541 10 66Organisation Institutionen för kulturgeografi och ekonomisk geografi Besöksadress: Geocentrum I, Sölvegatan 10, Lund Hämtställe: 16 WebbplatsNicklas Guldåkers profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år

https://www.cencip.lu.se/nicklas-guldaker - 2025-07-07

Potentials and limitations of 1D, 2D and coupled 1D-2D flood modelling in HEC-RAS

Översvämningsmodellering Idag används matematiska modeller, i form av datorprogram, för att simulera konsekvenser av framtida översvämningar. Det finns en stor uppsjö av modeller med olika möjligheter och begränsningar, så hur går vi egentligen till väga för att välja modell? Översvämningar hör till de naturliga katastrofer som gör störst skada. Mellan 1998 och 2009 krävde de 216 största översväHydraulic models can be used to predict the consequences of flooding events. In this project, three hydraulic models were constructed using the software HEC-RAS, and compared through a case study on Höje river catchment. The models include (i) a 1-dimensional (1D) model, where river and floodplain flow is modeled in 1D, (ii) a coupled 1D-2D model, where river flow is modeled in 1D and floodplain f

A vegetation map and a digital elevation model over the Kapp Linné area, Svalbard : with analyses of the vertical and horizontal distribution of the vegetation

A vegetation map and a Digital Elevation Model has been generated over a 54 km2 area situated at the western coast of Svalbard, at the Isfjorden fiord. The map is based on aerial photographs and a field survey made during the summer of 1994. The classification system used is described by Elven et alia (1990), for a similar study in Gipsdalen in the inner part of Isfjorden. The classification of th

Nya rättsmedel på upphandlingsområdet - om ogiltighetsförklaring, avtalsspärr, upphandlingsskadeavgift m.m.

Den svenska lagen på upphandlingsområdet för den klassiska sektorn, lagen om offentlig upphandling (LOU), bygger på upphandlingsdirektiv grundande på EU-fördragets bestämmelser om fri rörlighet för varor och tjänster. Rättsmedelsdirektivet, direktiv 89/665/EEG, som syftar till att säkerställa efterlevanden av upphandlingsreglerna, tillkom i början av 90-talet. Direktivet lämnade dock stort utrymmeThe Swedish law on procurement is based on Community Directives on public procurement establishing fundamental EU Treaty principles such as the principles of free movement of goods and services. The Remedies Directive (89/665/EEC), entering into force in the beginning of the 90´s, was adopted to ensure that effective and rapid remedies are available to aggrieved bidders. However, the directive let

Konkurrenters rättsskydd vid olagligt statsstöd - ett svenskt dilemma

Summary On 1 July 2013 the new state aid act entered into force. The preceding Inquiry had been instructed to consider whether special provisions were needed to enable third parties to bring actions before the Swedish courts with reference to the standstill obligation in Article 108.3 TFEU, and to leave suggestions for any legislation that might be needed in that respect. The Inquiry deemed such

Solceller med tillhörande lagringsbatteri i flerbostadshus

Titel: Solceller med tillhörande lagringsbatteri i flerbostadshus – Analys av lönsamhet och möjlighet att uppfylla kommande NNE-krav Författare: Frida Hansson, Christian Bakgrund: Den 1 januari 2021 träder nya, skärpta krav på byggnaders energiprestanda i kraft. Dessa krav kallas nära-nollenergikrav (NNE-krav) eftersom de tillkommer som en åtgärd för att öka antalet nära-nollenergibyggnader i SveTitle: PV-cells and storage batteries in multifamily residential buildings – Analysis of the profitability and the ability to meet the upcoming nearly zero-energy requirements Authors: Frida Hansson, Christian Jedhammar Supervisors: Karin Adalberth, Building Physics, LTH Ludvig Andersson, Teknik och hållbarhet, NCC Building SE Examiner: Åsa Wahlström, Installation Technology, LTH Problem: On 1 Jan

Oaktsam våldtäkt - vad utgör grov oaktsamhet? - En studie av domstolars resonemang gällande grov oaktsamhet i mål om våldtäkt alternativt oaktsam våldtäkt

In 2018, Sweden passed a new law regarding rape, which is based on consent. Prior to this, a certain amount of force or threat was required, but the current legislation is based on the lack of voluntary participation. A new offense was passed, negligent rape. Thus, criminal liability for rape does not only come in question in cases of intent, but also in cases of gross negligence. The main purpose

Svenska, språklig inriktning 1–40 poäng

Svenska, språklig inriktning 1–40 poäng Sommar 2020 Litteraturlista för SVEC05, Svensk grammatik och semantik i ett andraspråksperspektiv, 9 hp Fastställd av sektion 1 vid Språk- och litteraturcentrum den 29 april 2020. Obligatorisk kurslitteratur Ekberg, Lena. 2013. ”Grammatik och lexikon i svenska som andraspråk på nästan infödd nivå”. I Hyltenstam, K. & Lindberg, I. (red.) Svenska som andrasprå

https://www.sol.lu.se/media/utbildning/dokument/kurser/SVEC05/20201/SVEC05_litteraturlista_ST20_KLAR.pdf - 2025-07-08

Web RRSW 2021 5-X

314490_nr1_OMSL_RRSW_2021_5.indd RESEARCH REPORTS IN SOCIAL WORK 2021:5 School of Social Work | Lund University Hur har andrahandslägenheter i Malmö kommun fördelats till hemlösa över tid? En studie av prioriteringar och exkluderingar WEDDIG RUNQUIST SOCIALHÖGSKOLAN | LUNDS UNIVERSITET LUNDS UNIVERSITET Socialhögskolan ISBN 978-91-7895-539-8 www.soch.lu.se 9 7 8 9 1 7 8 9 5 5 3 9 8 Sv an en m är k

https://www.soch.lu.se/sites/soch.lu.se/files/2021-10/Web%20RRSW%202021_5-X.pdf - 2025-07-08

Metabolite-related dietary patterns pdf

Metabolite-related dietary patterns and the development of islet autoimmunity 1Scientific RepoRtS | (2019) 9:14819 | https://doi.org/10.1038/s41598-019-51251-4 www.nature.com/scientificreports Metabolite-related dietary patterns and the development of islet autoimmunity Randi K. Johnson 1, Lauren Vanderlinden2, Brian c. Defelice3, Katerina Kechris2, Ulla Uusitalo 4, oliver fiehn 3,5, Marci Sontag1

https://www.teddy.lu.se/sites/teddy.lu.se/files/metabolite-related_dietary_patterns_pdf.pdf - 2025-07-08

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children RESEARCH ARTICLE Open Access The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children Nicole M. Frank1* , Kristian F. Lynch2, Ulla Uusitalo2, Jimin Yang2, Maria Lönnrot3, Suvi M. Virtanen4,5,6,7, Heikki Hyöty3,8, Jill M

https://www.teddy.lu.se/sites/teddy.lu.se/files/the_relationship_between_breastfeeding_and_reported_respiratory_and_gastrointestinal_infection_rates_in_young_children_pdf.pdf - 2025-07-08