Filtyp
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15–20% of families fitting MODY criteria do not have mutations in any of the known genes. These families provide a rich resource for the identificat
One of the key ecological processes affected by climate change is plant carbon uptake. However, there is substantial uncertainty about how plant carbon uptake will respond to warming in mountain ecosystems, which are known for sharp temperature gradients and abrupt shifts in vegetation structure. Specifically, we lack an understanding of whether these response trajectories over time will be linear
Background and aim: Vitamin K has been proposed to have a preventive effect against arterial calcification through activation of the vitamin K dependent proteins and potentially protect against progression of atherosclerosis. Our aim was to assess the association between vitamin K status and vascular health in a general elderly population. Methods and results: In a cross-sectional study, the vitam
Accurate diagnosis of rare inherited anaemias is challenging, requiring a series of complex and expensive laboratory tests. Targeted next-generation-sequencing (NGS) has been used to investigate these disorders, but the selection of genes on individual panels has been narrow and the validation strategies used have fallen short of the standards required for clinical use. Clinical-grade validation o
Fluid biomarkers are revolutionizing the diagnosis and management of neurodegenerative diseases by enabling earlier diagnosis and disease monitoring. In particular, blood-based biomarkers have emerged as a minimally invasive and scalable alternative to cerebrospinal fluid analysis. Recent advances in blood-based tau biomarkers have shown high diagnostic accuracy for Alzheimer’s disease (AD). Other
OBJECTIVE: In a multicenter cohort of probable dementia with Lewy bodies (DLB), we tested the hypothesis that β-amyloid and tau biomarker positivity increases with age, which is modified by APOE genotype and sex, and that there are isolated and synergistic associations with the clinical phenotype. METHODS: We included 417 patients with DLB (age 45-93 years, 31% women). Positivity on β-amyloid (A+)
INTRODUCTION: We examined whether sex modifies the association between APOE ε2 and cognitive decline in two independent samples. METHODS: We used observational data from cognitively unimpaired non-Hispanic White (NHW) and non-Hispanic Black (NHB) adults. Linear mixed models examined interactive associations of APOE genotype (ε2 or ε4 carrier vs. ε3/ε3) and sex on cognitive decline in NHW and NHB p
The Sardinian dhole (Cynotherium sardous) was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene. Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African hunting doThe Sardinian dhole (Cynotherium sardous)1 was an iconic and unique canid species that was endemic to Sardinia and Corsica until it became extinct at the end of the Late Pleistocene.2-5 Given its peculiar dental morphology, small body size, and high level of endemism, several extant canids have been proposed as possible relatives of the Sardinian dhole, including the Asian dhole and African huntin
The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of environmental and genetic factors on variation in the parameters of innate and adaptive immune cells in homeostatic conditions, we combined standardized flow cytometry of blood leukocytes and genome-wide DNA genotyping of 1,000 healthy, unrelat
Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-Cas9 screen in a human MDS-derived cell line, MDS-L, and identify TOPORS as a loss-of-function target that synergizes with HMAs, reducing leukemic burden and i
The SCHOLAR-2 retrospective study highlighted poor overall survival (OS) with standard of care (SOC) regimens among patients with relapsed/refractory (R/R) mantle cell lymphoma (MCL) who failed a covalent Bruton tyrosine kinase inhibitor (BTKi). In the ZUMA-2 single-arm trial, brexucabtagene autoleucel (brexu-cel; autologous anti-CD19 CAR T-cell therapy) demonstrated high rates of durable response
PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin
Mantle cell lymphoma (MCL) after relapse is associated with poor prognosis. No standard of care exists and available evidence for treatments is limited, particularly in patients who fail Bruton tyrosine kinase inhibitor (BTKi) therapy. This multicentre retrospective chart review study, SCHOLAR-2, addresses this knowledge gap and reports on data collected from 240 patients with relapsed/refractory
Microsoft Word - HILMA 2008-09-06.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 33, 2007/08, Nr 2, 2007-09-06 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat p
https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht07_2_03.pdf - 2026-11-09
A Pathway for Increased Human Rights Knowledge in Africa Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human
https://rwi.lu.se/news/a-pathway-for-increased-human-rights-knowledge-generation-in-africa/ - 2026-11-10
Allmän studieplan för utbildning på forskarnivå Sida 1 av 19 Juridiska fakultetsstyrelsen ALLMÄN STUDIEPLAN Dnr U 2023/317 Datum 2023-05-24 Allmän studieplan för utbildning på forskarnivå för avläggande av juris doktorsexamen och juris licentiatexamen vid Juridiska fakulteten vid Lunds universitet 1. Identifikation Ämnen: allmän rättslära, arbetsrätt, bankrätt, civilrätt, EU-rätt, finansrätt, folk
Brevmall Postadress Box 207 221 00 Lund Besöksadress Lilla Gråbrödersgatan 4 Telefon dir 046-222 10 00, växel 046-222 00 00 Telefax 046- 222 11 61 E- post info@jur.lu.se Internet http://www.jur.lu.se Jur id iska faku l te tss tyre lsen Allmän studieplan för utbildning på forskarnivå för avläggande av juris doktorsexamen och juris licentiatexamen vid Juridiska fakulteten vid Lunds universitet 1. Id
Microsoft Word - 6 d Allmän studieplan förslag till revidering med SPÅRA ÄNDRINGAR 2026-09 slutlig Jur idiska fakul tetsstyrelsen ALLMÄN STUDIEPLAN 2026-10-01 1 (9) Dnr U 2026/569 Allmän studieplan för utbildning på forskarnivå för avläggande av juris doktorsexamen och juris licentiatexamen vid Juridiska fakulteten vid Lunds universitet 1. Identifikation Inriktningar: allmän rättslära, arbetsrätt,
https://www.jur.lu.se/sites/jur.lu.se/files/2026-10/Allm%C3%A4n%20studieplan%20fastst%C3%A4lld%202026-09-23.pdf - 2026-11-11
LUM nr 6 - 2005 I - - - - - - - - - - - - - - - - Full fart DisputeradeFull fart Disputerade på fund- bolivianerpå fund- bolivianer raisingen återvänderraisingen återvänder L U N D S U N I V E R S I T E T M E D D E L A R N U M M E R 6 J U N I 2 0 0 5 Å R G Å N G 3 8 MotMot hatten!hatten! II III Lunds universitets tidskrift LUM utkom första gången 1968. Den når i dag samtliga anställda och nästan l
https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-6-2005.pdf - 2026-11-11
