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News and events from 2022

News updates and events from the 2030 Graduate School. NewsDecemberReduced flow of plasticsAt Helsingborg's hospital, doctors have switched from disposable to reusable items and reduced the flow of plastics, writes Sjukhusläkaren. The Agenda 2030 PhD student Linn Boberg researches plastic articles in healthcare and is interviewed in the article.Tog bort onödiga verktyg - minskade plastflödet i ope

https://www.agenda2030graduateschool.lu.se/activities/news-2025/news-and-events-2022 - 2025-11-07

Clinical characteristics and outcomes of patients with Hodgkin lymphoma with central nervous system involvement : An international multicenter collaboration

Central nervous system (CNS) involvement is rare in patients with Hodgkin lymphoma (HL). Thus, the clinical features and outcomes are not well described. Cases of histologically confirmed CNS HL diagnosed between 1995 and 2015 were retrospectively identified in institutional (n = 7), national (n = 2), and cooperative group (n = 1) databases. We screened 30,781 patients with HL in our combined data

Radiosynthesis, biological evaluation and preliminary microPET study of 18F-labeled 5-resorcinolic triazolone derivative based on ganetespib targeting HSP90

Heat-shock protein 90 (HSP90) is a molecular chaperone that activates oncogenic transformation in several solid tumors, including lung and breast cancers. Ganetespib, a most promising candidate among several HSP90 inhibitors under clinical trials, has entered Phase III clinical trials for cancer therapy. Despite numerous evidences validating HSP90 as a target of anticancer, there are few studies o

Sequence analysis of HIV-1 isolates from Guinea-Bissau: selection of vaccine epitopes relevant in both West African and European countries.

For a CD8 epitope-based vaccine to match different geographic locations, the targeted epitopes for cytotoxic T-lymphocytes (CTLs) must be present in the local circulating HIV-1 strains. Secondly, the vaccine epitopes should match the host population HLA types. We characterized two new HIV-1 isolates from Guinea-Bissau. Also, we have identified 15 subdominant CD8 epitopes representing common HLA su

Early initiated noradrenaline versus fluid therapy for hypotension and shock in the emergency department (VASOSHOCK): a protocol for a pragmatic, multi-center, superiority, randomized controlled trial

BackgroundShock is a condition with high mortality even with early intervention and treatment. Usual care for shock and hypotension in the Emergency Department (ED) is intravenous fluid resuscitation which can lead to fluid overload and other complications. When fluid therapy fails or risk of complications are high, the next treatment step is the use of vasopressors for stabilisation. Noradrenalin

Air pollution-induced proteomic alterations increase the risk of child respiratory infections

Early life air pollution exposure may play a role in development of respiratory infections, but underlying mechanisms are still not understood. We utilized data from two independent prospective birth cohorts to investigate the influence of prenatal and postnatal ambient air pollution exposure of PM2.5, PM10 and NO2 on maternal and child proteomic profiles and the risk of daily diary-registered com

Subclinical atherosclerosis in patients with cyanotic congenital heart disease

Introduction: Survival in patients with cyanotic congenital heart disease (CCHD) has improved dramatically. The result is an ageing population with risk of acquired heart disease. Previous small uncontrolled studies suggested that these patients are protected against the development of atherosclerosis. To test this hypothesis, we sought to determine the prevalence of subclinical atherosclerosis in

Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

Changes in gene regulation and expression govern orderly transitions from hematopoietic stem cells to terminally differentiated blood cell types. These transitions are disrupted during leukemic transformation, but knowledge of the gene regulatory changes underpinning this process is elusive. We hypothesized that identifying core gene regulatory networks in healthy hematopoietic and leukemic cells

The use of synthetic peptides for detection of anti-citrullinated protein antibodies in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology. A characteristic feature of RA is the presence of anti-citrullinated protein antibodies (ACPA). Since ACPAs are highly specific for RA and are often present before the onset of RA symptoms, they have become valuable diagnostic and prognostic. As a result, several assays for detection of ACPAs exist, which vary in sensitivity a

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients : the DecubICUs study

PURPOSE: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients.METHODS: International 1-day point-prevalence study; follow-up for outcome assessment unti

Microsoft Word - HILMA 2007-08-17.doc

Microsoft Word - HILMA 2007-08-17.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 33, 2007/08, Nr 1, 2007-08-17 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat p

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht07_1_03.pdf - 2025-11-06

Lars Eklundh

Professor Kontaktinformation E-post: lars [dot] eklundh [at] nateko [dot] lu [dot] se Telefon: +46 46 222 96 55Organisation Institutionen för naturgeografi och ekosystemvetenskap Besöksadress: Sölvegatan 12, Lund Rumsnummer: 450 Hämtställe: 16 WebbplatsLars Eklundhs profil i Lunds universitets forskningsportalAndra roller Forskare MERGE: ModElling the Regional and Global Earth system Lärare Instit

https://www.nateko.lu.se/sv/lars-eklundh - 2025-11-08

Föräldraskapande - En kritisk undersökning av den rättsliga konstruktionen av föräldraskap med särskilt fokus på regleringen av föräldraskap vid ändrad könstillhörighet

Since July 1, 2013, there is no longer a sterilization requirement for transgender persons who want to transition. This paper critically examines the new legislation in the Parental Code, which entered into force on January 1, 2019 as a result of the abolished sterilization requirement. The new legislation applies to parenthood when one or both parents have changed their legal gender. Before the n

Barnfridsbrottet - ändamålsenligt utifrån barnets bästa?

Fysiskt och psykiskt våld förekommer i många hem i Sverige. Allt för många barn växer upp med att få se, höra och uppleva detta våld. Under de senaste åren har forskning tydligt visat att barn som bevittnat våld inom familjen påverkas väldigt negativt. De känner ofta en känsla av maktlöshet, övergivenhet och skam. För att stärka barnets rättsliga ställning har det tidigare införts en straffskärpnPhysical and psychological violence exist in many homes in Sweden. Far too many children have grown up with witnessing, hearing and experience the violence. In recent years research has shown that children who witness violence within the family gets profoundly affected. They often feel a sense of powerlessness, abandonment, and shame. To strengthen the legal position of the child, a basis for aggr

Förslaget om säkerhetsstraff - En kritisk analys mot bakgrund av påföljdsbestämningens grundläggande syften och principer

In July 2024, the Inquiry on Sanctions, Recidivism, and Enforcement submit-ted its report, SOU 2024:48, which includes a proposal to introduce a preventively oriented, indefinite deprivation of liberty as a sanction, referred to as a security sentence. The purpose of the proposal is to enable the indefinite detention of an offender in particularly serious situations, where the sanction cannot be d

Konformitetsprincipens gränsmarker - Med inriktning mot unga lagöverträdare och en sänkning av straffmyndighetsåldern

Konformitetsprincipen är den grundläggande rättsprincipen i den straffrätts-liga ansvarsläran som ger besked om att den som inte hade förmåga eller tillfälle att kunna rätta sig efter lagen inte bör bli straffrättsligt ansvarig för ett brott. Detta eftersom ett straffansvar i den situationen hade varit orätt-färdigt och meningslöst. Den som inte kunde rå för sin brottsliga gärning ska således inteThe Conformity Principle is a fundamental legal principle within the Swedish system of criminal liability that states that those who did not have capacity or opportunity to act in accordance with the criminal law should not be punished for a crime. Numerous rules and several legal principles can be derived from The Conformity Principle. The rationale behind the Conformity Principle is that it woul

Strävan efter en skyndsam handläggning på bekostnad av VBU-utredningarnas kvalitet? - En studie beträffande effekterna av tidsinskränkningen i 6 kap. 19 § tredje stycket föräldrabalken

På senare år har det skett en bred förskjutning i synen på barn- och föräldrarätt. Ett starkare barnrättsperspektiv har etablerats inom svensk rätt och politik. Flera ändringar har gjorts i föräldrabalken. En av dessa ändringar återfinns i 6 kap. 19 § tredje stycket föräldrabalken. I proposition 2020/21:150 föreslog den dåvarande regeringen en lagstadgad tidsgräns på fyra månader när det kommer tiIn recent years, there has been a broad shift in the view of children’s and parental rights. A stronger children’s rights perspective has been established within Swedish law and politics. Several amendments have been made to the Children and Parents Code. One of these amendments can be found in Chapter 6, Section 19, third paragraph of the Children and Parents Code (sw. föräldrabalken (1949:381)).