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JW-MDS#130009 1..9 Study of the Antidyskinetic Effect of Eltoprazine in Animal Models of Levodopa-Induced Dyskinesia Erwan Bezard, PhD,1,2,3 Elisabetta Tronci, PhD,4,5 Elsa Y. Pioli, PhD,6 Qin Li, PhD,3,6 Gregory Porras, PhD,6 Anders Bj€orklund, MD,5 and Manolo Carta, PhD4,5* 1Institute for Neurodegenerative Diseases, Bordeaux University, Bordeaux, France 2Institute for Neurodegenerative Diseases,

https://www.neurobiology.lu.se/sites/neurobiology.lu.se/files/publication_in_mov_disord.pdf - 2025-12-09

English is widely recognized as the language of science, and English-language publications (ELPs) are rapidly increasing. It is often assumed that the number of non-ELPs is decreasing. This assumption contributes to the underuse of non-ELPs in conservation science, practice, and policy, especially at the international level. However, the number of conservation articles published in different langu

BACKGROUND: Endolichenic fungi are microbes that inhabit the thalli of lichens and produce various unique chemicals that can be used for pharmaceutical purposes.PURPOSE: This study screened a library of endolichenic fungal extracts to identify novel anticancer agents capable of suppressing the tumorigenicity of human cancer cells.METHODS: Active compounds were isolated from extracts of endolicheni

Climate change is a global and demanding issue, which affects all the states on the planet. The European Union has from the 90s been vigorously engaged in the international efforts to tackle climate change and even pursued to take on the leading role in the global climate regime. The two most anticipated UN conferences for combating climate change at the global level were the COP15 in 2009 and COP

The production of eggs, meat, and dairy products in the EU indirectly contributes to deforestation and ecosystem conversion (DEC) in Latin America due to extensive imports of soy for animal feed. This thesis explores under which preconditions the mandatory European Sustainability Reporting Standards for the agriculture and farming sector can increase transparency in the opaque soy supply chains an

Enzymes are often considered a green approach next to conventional fossil-based chemicals helping us on the margin towards a low-impact society. While enzyme catalysed reactions are low environmental impact technologies, their production is not. In this study, a comparative life cycle assessment of different recombinant enzyme manufacturing strategies quantifies and evaluates the contribution of d

Purpose: The purpose of the thesis is to explore how the ownership transfer from a developed country to a developing country influences consumers’ perception of the brand. Design/methodology/approach: After the extensive review of the literature about the concept of country of origin and brand image, three premium automobile brand acquisition cases (Jaguar, Land Rover and Volvo) were investigated.

Under 1900-talet såg världen omfattande lidande bland mänskligheten i flera länder, vilka kulminerade i folkmord och massakrer under 1990-talet. Ett sätt som identifierades för att få ett slut på grymma brott var humanitära interventioner. En kommission, The International Commission on Intervention and State Sovereignty (ICISS), tillsattes år 2001 för att utreda begreppet. De presenterade i decembDuring the 20th century, the world saw humans suffering in many countries around the world. These sufferings ended in genocide and massacres during the 1990s. One way that was identified to end atrocity crimes was humanitarian interventions. A commission, The International Commission on Intervention and State Sovereignty (ICISS), was appointed in 2001 to investigate the concept. They presented a n

Den internationella havsrättsdomstolen (ITLOS), inrättad under FN:s havs-rättskonvention (UNCLOS), utgör en avgörande tvistlösningsmekanism vid lösandet av havsrättsliga tvister. I takt med att världens hav blir viktigare för handel, resurser och miljömässig stabilitet, erbjuder ITLOS en specialiserad rättslig ram för att lösa tvister. Uppsatsen undersöker hur effektivt ITLOS kan verkställa sina The International Tribunal for the Law of the Sea (ITLOS), established under the United Nations Convention on the Law of the Sea (UNCLOS), plays a vital role in resolving disputes about maritime law. As the world’s oceans become more important for trade, resources and environmental stability, ITLOS provides a specialized legal framework to address conflicts. This thesis examines how effective ITLO

This research and policy brief focuses on conflict and displacement as key factorscontributing to statelessness and barriers to acquiring and holding Myanmar citizenship. The brief is designed as a working document for discussing important issues relevant for local governance during the revolution and national and state-level governance in the future. To aid in these conversations and policy devel

As information technology develops in the past decade, the digital society has affected every aspect of the social structure. The legal system faces the challenge in implementing the legal norms, yet the evolved architecture of technology in the digital society makes it difficult for the law to perform its function. One of the fields of challenge is legal protection of personal data. Legislat

Huvudregeln gällande en stats brukande av våld framgår av artikel 2(4) i Förenta nationernas stadga. Av artikeln så framgår ett förbud för såväl hot som bruk av våld. Då det görs i syfte att inskränka en annan stats politiska oberoende eller territoriella integritet. Till detta så förbjuds även sådana hot eller bruk av våld som kan anses vara oförenligt med Förenta nationernas värdegrund. Av artikArticle 2(4) of the Charter of the United Nations presents the general rule regarding states use of force in international relations. The article states that all members are obliged to refrain from threat or use of force against another member states political independence or territorial integrity. Additionally, actions of threats or use of force that are in violation of the purposes of the United

Determining the appropriate duration for traffic conflict observation remains a critical yet unresolved challenge in road safety analysis. Existing approaches lack a quantitative approach to determine adequate sample sizes for general conflict-based applications. This study addresses this gap by proposing an extreme value theory based framework to determine appropriate observation durations, based

Background & Aims Predniso(lo)ne, alone or in combination with azathioprine, is the standard-of-care (SOC) therapy for autoimmune hepatitis (AIH). However, the SOC therapy is poorly tolerated or does not control disease activity in up to 20% of patients. We assessed the efficacy of mycophenolate mofetil (MMF) and tacrolimus as second-line therapy for patients with AIH. Methods We performed a r