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On the role of language constructs for framework design

The relationship between framework design and language constructs are discussed for two reasons: firstly, designing frameworks requires the ability to give the framework designer precise control over aspects of the framework extensions; secondly, the framework constraints should be specified such that they are statically checkable. Four existing language constructs are discussed: generalized block

Life cyle and sexuality of the freshwater raphidophyte Gonyostomum semen (Raphidophyceae)

Previously unknown aspects in the life cycle of the freshwater flagellate Gonyostomum semen (Ehrenb.) (Raphidophyceae) are described here. This species forms intense blooms in many northern temperate lakes, and has increased in abundance and frequency in northern Europe during the past decades. The proposed life cycle is based on observations of life cycle stages and transitions in cultures. Viabl

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

Recent studies in Drosophila have shown that heparan sulfate proteoglycans (HSPGs) are required for Wingless (Wg/Wnt) signaling. In addition, genetic and phenotypic analyses have implicated the glypican gene daily in this process. Here, we report the identification of another Drosophila glypican gene, daily-like (dly) and show that it is also involved in Wg signaling. Inhibition of dly gene activi

Factors affecting color Doppler energy ultrasound recordings in an in-vitro model

Compared to conventional color Doppler ultrasound imaging, the new color Doppler modality "color Doppler energy" (CDE) has improved the possibility of visualizing blood vessels having low blood-flow velocities, but appears to be influenced by the settings of the ultrasound instrument and motion artefacts. The aim of this methodological study was to evaluate the effects of the different factors on

Performance of simultaneous emission-transmission systems for attenuation-corrected SPEct: a method for validation applied to two camera systems

Several commercially available systems for attenuation correction in single photon emission computed tomography (SPECT) based on a transmission scan have been introduced that vary in performance. A test procedure for attenuation correction in SPECT is described and applied to two principally different gamma camera systems (the Siemens Multispect 3 triple-headed system [3HS] and the ADAC Genesys Ve

Nonoperative Management of Blunt Splenic Trauma: Also Feasible and Safe in Centers with Low Trauma Incidence and in the Presence of Established Risk Factors

Background: Treatment of blunt splenic trauma has undergone dramatic changes over the last few decades. Nonoperative management (NOM) is now the preferred treatment of choice, when possible. The outcome of NOM has been evaluated. This study evaluates the results following the management of blunt splenic injury in adults in a Swedish university hospital with a low blunt abdominal trauma incidence.

Boundary layer control on convective available potential energy: Implications for cumulus parameterization

[1] Convective available potential energy (CAPE), frequently regarded as an indicator of the potential intensity of deep convection, is strongly controlled by the properties of the planetary boundary layer (BL). Variations in CAPE observed during field experiments in midcontinent North America, the tropical east Atlantic, and the tropical west Pacific, can be accounted for mostly by changes in the

Purification and characterization of five cellulases and one xylanase from Penicillium brasilianum IBT 20888

The filamentous fungus Penicillium brasilianum IBT 20888 was cultivated on a mixture of 30 g l−1 cellulose and 10 g l−1 xylan for 111 h and the resulting culture filtrate was used for protein purification. From the cultivation broth, five cellulases and one xylanase were purified. Hydrolysis studies revealed that two of the cellulases were acting as cellobiohydrolases by being active on only micro

Dementia in First-Degree Relatives of Patients with Frontotemporal Dementia. A Family History Study.

Several studies have found a clustering of dementia in relatives of patients with frontotemporal dementia (FTD). This study analysed the familial aggregation of FTD specifically as well as the occurrence of dementia in general in first-degree relatives of patients with FTD. A family history study was carried out on 478 first-degree relatives of 74 index patients suffering from FTD. Cases of organi

Tidal facies in the Upper Silurian Oved-Ramsasa Group of Scania, Sweden: Linkages of radial and cerebroid ooids and evaporite tracers to subtidal, lagoonal environment

A sequence in the Upper Silurian Oved-Ramsasa Group in Scania, Sweden has been investigated sedimentologically and geochemically. This sequence represents a regressive marine succession. The sedimentary structures and the rapid vertical changes in lithologies and the lateral variability of beds indicate a tide-dominated sedimentation in a shallow epeiric sea, where even small oscillations in sea w

Oxidation and reduction behavior of Ge/Si islands

We have investigated the oxidation/reduction behavior of dome-shaped three-dimensional islands of Ge on Si(001) grown by ultrabigh vacuum chemical vapor deposition. The oxidation was done by exposing the surfaces to H2O steam in N-2. The reduction was done by H-2, which selectively reduces only the GeO2. The results of the oxidation/reduction processes under varying conditions were analyzed by hig

Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres.

Carcinomas of the head and neck typically exhibit complex chromosome aberrations but the underlying mutational mechanisms remain obscure. Evaluation of cell division dynamics in low-passage cell lines from three benign and five malignant head and neck tumours revealed a strong positive correlation between multipolarity of the mitotic spindle and the formation of bridges at anaphase in both benign

Driver comprehension and acceptance of the active accelerator pedal after long-term use

Driver comprehension and acceptance of the active accelerator pedal (AAP) after long-term use were evaluated in a large-scale Swedish trial held in 2000-2002. The system was installed in the cars of 281 test drivers who then used it for between six months and a year. The participants' responses, elicited by questionnaires in the end of the trial, showed a positive rating of the concept of the AAP,

The effects of plant density upon pollination success, reproductive effort and fruit parasitism in Cistus ladanifer L. (Cistaceae)

Human activity often causes a decline in the local density of plant populations. Below some critical lower density, populations may suffer a progressive decline in reproductive success because of the difficulties associated with finding suitable mates. Therefore, to conserve endangered plant species it is necessary to understand in greater detail how changes in population density affect different

Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals.

Dendritic cells (DCIs) possess a potent ability to modulate and activate specific T-cell responses to allergens, which play a pivotal role in allergic inflammation by secreting cytokines and other mediators. However, the molecular mechanisms by which allergen-challenged DCs regulate specific T-cell responses are still not well characterized. This study aims at elucidating the molecular mechanisms

Online monitoring of urea concentration in dialysate with dual-beam Fourier-transform near-infrared spectroscopy

The robustness of a dual-beam, optical null, Fourier-transform near-infrared (FTNIR) spectrometer was investigated by means of online, near-infrared measurements and predictions of urea concentrations in spent dialysate during hemodialysis treatment. Simple multivariate calibration using a few factors based on a small number of prepared samples provided stable and accurate predictions over a perio